Promoting Knowledge Economy Organisations and Innovative Work: Regional influences on Knowledge-based Small and Medium-sized Enterprise clusters in Australia and Germany. In both Australia and Germany many regional areas have experienced economic and social decline. Clusters offer a means of fostering local economic development thereby arresting regional social and economic deterioration. The research focuses on those clusters that rely on knowledge transfer between organisations. Through identi ....Promoting Knowledge Economy Organisations and Innovative Work: Regional influences on Knowledge-based Small and Medium-sized Enterprise clusters in Australia and Germany. In both Australia and Germany many regional areas have experienced economic and social decline. Clusters offer a means of fostering local economic development thereby arresting regional social and economic deterioration. The research focuses on those clusters that rely on knowledge transfer between organisations. Through identifying the drivers and impediments to the formation of knowledge based clusters, the research aims to provide practical guidance to regionally-based organizations to assist in the successful formation and maintenance of clusters. In doing so, the research will identify how clusters that rely on the sharing of organizational knowledge may promote greater regional employment possibilities.Read moreRead less
Environmental and Social Responsibility in the Small and Medium Sized Enterprise Sector: Challenges and Prospects. The proposed research addressed two of the National Research Priorities, viz., promoting an environmentally sustainable Australia (Goal 2: Transforming existing industries), and promoting and maintaining good health (Goal 4: strengthening Australia's social and economic fabric). The research findings will identify best practices in the areas of environmental and social responsibili ....Environmental and Social Responsibility in the Small and Medium Sized Enterprise Sector: Challenges and Prospects. The proposed research addressed two of the National Research Priorities, viz., promoting an environmentally sustainable Australia (Goal 2: Transforming existing industries), and promoting and maintaining good health (Goal 4: strengthening Australia's social and economic fabric). The research findings will identify best practices in the areas of environmental and social responsibility in the SME sector thus contributing to the creation of environmentally and socially sustainable workplaces. By integrating perspectives from multiple stakeholders the research also addresses community environmental and social concerns.Read moreRead less
Development Of Iron Complexes For The Treatment Of FriedreichÍs Ataxia & The Role Of Frataxin In Iron Metabolism
Funder
National Health and Medical Research Council
Funding Amount
$616,143.00
Summary
Friedreich's ataxia (FA) is a neuro- & cardio-degenerative disease where there is an accumulation of toxic iron (Fe) in the mitochondrion. Work from our current NHMRC grant showed iron plays a significant role in FA pathology In fact, the CIs dissected the mechanisms of mitochondrial iron-loading & have published 8 papers in high impact journals with 3 papers in PNAS USA in the last 2 yrs Understanding of this process has led to the design of rationalised drugs for FA This work in this Renewal c ....Friedreich's ataxia (FA) is a neuro- & cardio-degenerative disease where there is an accumulation of toxic iron (Fe) in the mitochondrion. Work from our current NHMRC grant showed iron plays a significant role in FA pathology In fact, the CIs dissected the mechanisms of mitochondrial iron-loading & have published 8 papers in high impact journals with 3 papers in PNAS USA in the last 2 yrs Understanding of this process has led to the design of rationalised drugs for FA This work in this Renewal could lead to novel therapies for FARead moreRead less
Understanding The Mechanisms For Ameliorating/preventing Antipsychotic-induced Obesity In Early Life
Funder
National Health and Medical Research Council
Funding Amount
$576,496.00
Summary
There has been a sharp worldwide increase during the last decade in antipsychotic prescriptions (mostly “off-label”) to paediatric patients. One important issue is that antipsychotic drugs were developed for adult patients and normally have serious side-effects. This project will not only reveal the mechanisms of antipsychotic-induced obesity side-effects in youth, but will also explore intervention strategies for preventing antipsychotic-induced weight gain/obesity in paediatric patients.
I am a cancer cell biologist investigating molecular mechanisms of leukaemia cell resistance to chemotherapeutic drugs, and novel strategies for the management of high risk or relapsed disease. For these purposes I have developed orthotopic xenograft mode
How can Small Economies Create Globally Competitive Firms in New High-Tech Industries? In today's competitive world, governments have to develop better policies to stimulate economic growth. This research will provide Australian policy makers systematic empirical evidence to develop a dedicated policy aimed at stimulating the internationalization of new ventures in biotechnology, which constitutes a frontier high-tech area. Our study and the policy recommendations that will emerge from it can ha ....How can Small Economies Create Globally Competitive Firms in New High-Tech Industries? In today's competitive world, governments have to develop better policies to stimulate economic growth. This research will provide Australian policy makers systematic empirical evidence to develop a dedicated policy aimed at stimulating the internationalization of new ventures in biotechnology, which constitutes a frontier high-tech area. Our study and the policy recommendations that will emerge from it can have a big economic impact because the health sector in biotechnology is a growing hi-tech area and has much potential to create value for the society. Read moreRead less