Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100074
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will d ....Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will drive innovation across a range of critical social issues that require integrated data for research and social innovation including healthcare, better outcomes for disadvantaged and vulnerable groups, resilient urban, rural and regional communities, and increasing our capacity to respond to climate change. Read moreRead less
ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less
Defining the Status of Culturally and Linguistically Diverse Young People. This project aims to improve the social cohesion of Australian society and the living standards of a significant group of our young people. Around 25 per cent of all Australians aged 12 to 24 are from culturally and linguistically diverse (CALD) backgrounds. In collaboration with nine Australian organisations, the project aims to critically define the status of CALD youth; develop the first national status reporting frame ....Defining the Status of Culturally and Linguistically Diverse Young People. This project aims to improve the social cohesion of Australian society and the living standards of a significant group of our young people. Around 25 per cent of all Australians aged 12 to 24 are from culturally and linguistically diverse (CALD) backgrounds. In collaboration with nine Australian organisations, the project aims to critically define the status of CALD youth; develop the first national status reporting framework for the group that will generate new social, economic and cultural indicators; and build a knowledge hub to store and curate CALD youth data. Data and understanding from this project is intended to enable governments to meet the group’s specific needs and enhance their opportunities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100067
Funder
Australian Research Council
Funding Amount
$10,000,000.00
Summary
Australian Membership of the International Ocean Discovery Program. Australian membership of the International Ocean Discovery Program:
This project is for a 5-year membership of the International Ocean Discovery Program, the world’s largest collaborative research program in earth and ocean sciences addressing international priorities. The program conducts seagoing coring expeditions and monitoring of instrumented boreholes to study the history and current activity of the Earth, recorded in sed ....Australian Membership of the International Ocean Discovery Program. Australian membership of the International Ocean Discovery Program:
This project is for a 5-year membership of the International Ocean Discovery Program, the world’s largest collaborative research program in earth and ocean sciences addressing international priorities. The program conducts seagoing coring expeditions and monitoring of instrumented boreholes to study the history and current activity of the Earth, recorded in sediments and rocks below the seafloor. The program’s aims include understanding past global environments on multiple time scales, the deep biosphere, plate tectonics, occurrence and distribution of resources, and generation of hazards. Several multinational expeditions are scheduled and planned in our marine jurisdiction and within the Australasian region. Read moreRead less
ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, s ....ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, strengthen international collaboration, and involve and inform end-point users. It will foster research which responds to the aspirations and needs of older Australians and informs action that can improve experiences of individual and population ageing.Read moreRead less
Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have change ....Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have changed over long periods of time is vital to understanding the nature of the system itself. The project intends to track changes in the diet of Adélie penguins from serially preserved ancient fecal (guano) remains dating back approximately 30,000 years. These remains are known to contain microscopic remnants of penguin prey.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100047
Funder
Australian Research Council
Funding Amount
$3,600,000.00
Summary
Australian Membership of the International Ocean Discovery Program. Australian membership of the International Ocean Discovery Program: This project is for an Australian membership of the International Ocean Discovery Program. The Program will recover drill cores, situate observatories, and conduct down-hole experiments in all the world's oceans from lowest to highest latitudes to address fundamental questions about Earth's history and processes within four high-priority scientific themes: clima ....Australian Membership of the International Ocean Discovery Program. Australian membership of the International Ocean Discovery Program: This project is for an Australian membership of the International Ocean Discovery Program. The Program will recover drill cores, situate observatories, and conduct down-hole experiments in all the world's oceans from lowest to highest latitudes to address fundamental questions about Earth's history and processes within four high-priority scientific themes: climate and ocean change - reading the past and informing the future; biosphere frontiers - deep life, biodiversity, and environmental forcing of ecosystems; earth connections - deep processes and their impact on earth's surface environment; earth in motion - processes and hazards on a human time scale.Read moreRead less
When Sinks Become Sources;
Understanding Persistent Organic Pollutant Behaviour in Dynamic Polar Environments. Polar regions are environmental ‘sinks’ for man-made, Persistent Organic Pollutants (POPs). The unique biogeochemical processes governing POP behaviour in the Polar landscape are not understood, yet are necessary to predict their impact in polar ecosystems. The Antarctic seasonal-ice zone provides an archetype for multi-compartment, temporal observations of POP partitioning in respons ....When Sinks Become Sources;
Understanding Persistent Organic Pollutant Behaviour in Dynamic Polar Environments. Polar regions are environmental ‘sinks’ for man-made, Persistent Organic Pollutants (POPs). The unique biogeochemical processes governing POP behaviour in the Polar landscape are not understood, yet are necessary to predict their impact in polar ecosystems. The Antarctic seasonal-ice zone provides an archetype for multi-compartment, temporal observations of POP partitioning in response to the major drivers of ice cover and primary productivity. In addition, the major Antarctic POP reservoirs of seawater and ice will be characterised. Empirical data will be used to parameterise a regional fugacity model. Model application to varying climate scenarios will extend our understanding of POP behaviour and threat in polar regions.Read moreRead less