Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maint ....Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maintain psychosocial wellbeing. This project expects to generate new knowledge in recruiting, retaining, and deferring older blood donors. Expected outcomes include tailored, validated resources that may significantly benefit Australia by effectively engaging older adults to ensure the sustainability of the blood supply.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Social Futures & Life Pathways of Young People in Queensland: Waves 6 & 7. This project plans to extend a large longitudinal study of young people in Queensland to investigate the impact of social, political and economic changes on educational, workforce, partnering, family and housing transitions in early adulthood. The project is designed to combine large-scale survey research with in-depth qualitative interviewing to track stability and change in the values, aspirations, health and wellbeing ....Social Futures & Life Pathways of Young People in Queensland: Waves 6 & 7. This project plans to extend a large longitudinal study of young people in Queensland to investigate the impact of social, political and economic changes on educational, workforce, partnering, family and housing transitions in early adulthood. The project is designed to combine large-scale survey research with in-depth qualitative interviewing to track stability and change in the values, aspirations, health and wellbeing of a cohort of young people who were first surveyed as secondary school students a decade earlier. This aims to inform social policy by identifying factors that promote positive career, relationship, housing and health outcomes for young adults, and those which place young adults at risk of unemployment, tertiary non-completion, residential and relationship instability, and poorer mental and physical wellbeing.Read moreRead less
Special Research Initiatives - Grant ID: SR0354531
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Social research network for sustainable rural communities. The triple bottom line of social, economic and environmental imperatives forms the accepted ingredients of sustainability. While the economic and environmental dimensions have been relatively well researched, there is insufficient understanding of the socio-cultural dimensions and how these determine environmental and health outcomes. The interactions between the dimensions are also poorly understood. While there are some researchers in ....Social research network for sustainable rural communities. The triple bottom line of social, economic and environmental imperatives forms the accepted ingredients of sustainability. While the economic and environmental dimensions have been relatively well researched, there is insufficient understanding of the socio-cultural dimensions and how these determine environmental and health outcomes. The interactions between the dimensions are also poorly understood. While there are some researchers in this field, they have tended to work in isolation. The development of a resourced interdisciplinary network to facilitate collaboration will increase the contribution and innovativeness of their collective research and contribute to understanding socio-economic determinants of dynamic regions and healthy rural communities.Read moreRead less
Optimising the roles of online communities in rural resilience . This research will use data from online communities to identify roles they do, and could play, in rural resilience. It uses social media analytics and spatial methodology to taxonomise and map service topics and social resilience from online communities. Governments call for rural service innovation. To date, robust evidence about online versus local services needed, is lacking. This is partly due to lack of data about diverse cons ....Optimising the roles of online communities in rural resilience . This research will use data from online communities to identify roles they do, and could play, in rural resilience. It uses social media analytics and spatial methodology to taxonomise and map service topics and social resilience from online communities. Governments call for rural service innovation. To date, robust evidence about online versus local services needed, is lacking. This is partly due to lack of data about diverse consumers' priorities and gaps. Social media could offer latent insights, but ethical methodology producing useful de-identified policy insights has been lacking. This study exemplifies applying social media data analytics at scale to address policy problems and will produce up-to-date co-designed data use guidelines.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100074
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will d ....Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will drive innovation across a range of critical social issues that require integrated data for research and social innovation including healthcare, better outcomes for disadvantaged and vulnerable groups, resilient urban, rural and regional communities, and increasing our capacity to respond to climate change. Read moreRead less
Social futures and life pathways of young people in Queensland: waves 4 and 5 of a longitudinal study. This project assesses the impact of globalisation on the attitudes, behaviors, and life pathways of a cohort of over 7000 young Queenslanders, first surveyed when they were aged 12 and 13. Participants will be followed up when they are aged 19 and 20 and 20/21 to examine their experiences of the transition from school to work, family and social life.