Improved cryopreservation protocols for long term storage of platelets. The aim of this project is to characterise human blood platelet deterioration during cold storage and cryopreservation, and accelerate the development of improved long-term storage options. The project expects to generate important new knowledge about how platelets deteriorate during storage, and how such deterioration can be minimized. The expected outcomes are improved methods for long term platelet storage. This should be ....Improved cryopreservation protocols for long term storage of platelets. The aim of this project is to characterise human blood platelet deterioration during cold storage and cryopreservation, and accelerate the development of improved long-term storage options. The project expects to generate important new knowledge about how platelets deteriorate during storage, and how such deterioration can be minimized. The expected outcomes are improved methods for long term platelet storage. This should benefit blood donation services and hospitals by improving platelet delivery to remote locations, reducing wasted blood and the number of donations required, leading to significant financial savings.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100186
Funder
Australian Research Council
Funding Amount
$370,000.00
Summary
Advanced biophysical characterisation centre (ABCC). The Advanced Biophysical Characterisation Centre shared between RMIT and the University of Melbourne will provide a comprehensive suite of techniques for the study of problems in membrane biophysics, protein and biomolecular assembly and the nanosciences, with applications to health, environmental science and advanced technologies.
Two dimensional conjugated polymers: a new class of functional nanomaterials. New technologies depend on the design and development of novel materials. This project will synthesise a new class of materials, namely two dimensional conjugated polymers, which have enormous potential for creating new technologies, for example in electronics and sensing.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100090
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Surface and Colloid Characterisation Facility. Surface and colloid characterisation facility: Surface science lies at the heart of biointerface and colloid science. This facility will enable particle size, shape, distribution, surface area and charge to be measured as well as the amount of material adsorbed to interfaces, the configuration of that material and the response of the surface to stimuli such as changing pH or salinity. All these parameters influence the properties of these important ....Surface and Colloid Characterisation Facility. Surface and colloid characterisation facility: Surface science lies at the heart of biointerface and colloid science. This facility will enable particle size, shape, distribution, surface area and charge to be measured as well as the amount of material adsorbed to interfaces, the configuration of that material and the response of the surface to stimuli such as changing pH or salinity. All these parameters influence the properties of these important systems. As such this facility will underpin the research of a number of groups across three institutions over the next decade and promote collaboration between scientists with a range of complementary expertise in fields where surface science is important from biology to ionic liquids.Read moreRead less
Linking topology and rheology for designing supramolecular polymer networks. This project aims to develop a foundation for understanding how microscopic topology and intermolecular interactions control the flow behaviour of supramolecular polymer networks. Brownian dynamics algorithms will be developed to unravel the complex dynamics of the network and calibrated by comparison with carefully designed experiments. The expected outcome of the project is a quantitative framework for connecting the ....Linking topology and rheology for designing supramolecular polymer networks. This project aims to develop a foundation for understanding how microscopic topology and intermolecular interactions control the flow behaviour of supramolecular polymer networks. Brownian dynamics algorithms will be developed to unravel the complex dynamics of the network and calibrated by comparison with carefully designed experiments. The expected outcome of the project is a quantitative framework for connecting the molecular structure and energy landscape with resulting macroscopic properties. This project should yield significant benefit in the rational design of supramolecular systems in which the thermorheological properties can be tuned over a wide range of force/time scales with applications spanning from enhanced oil recovery to injectable hydrogels.Read moreRead less
Rational design of new synthetic antifreeze molecules for cryopreservation. This project aims to synthesise new carbohydrate-based surfactants optimised for use as cryoprotectants, and to accurately measure, model and optimise their performance. The project will use state-of-the-art experimental methods and advanced phase-field modelling techniques to optimise the cryoprotectants so that they reduce osmotic stress in cells and inhibit ice crystal growth during freezing and thawing. The expected ....Rational design of new synthetic antifreeze molecules for cryopreservation. This project aims to synthesise new carbohydrate-based surfactants optimised for use as cryoprotectants, and to accurately measure, model and optimise their performance. The project will use state-of-the-art experimental methods and advanced phase-field modelling techniques to optimise the cryoprotectants so that they reduce osmotic stress in cells and inhibit ice crystal growth during freezing and thawing. The expected outcomes will be novel cryoprotectants that are easy to synthesise, non-toxic and effective, opening up new possibilities for the cryopreservation of cells, organs and possibly even whole organisms. This will have broad impact in critical applications such as long-term blood storage, reproductive technology and stem cell therapy, as well as preservation of endangered species.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100192
Funder
Australian Research Council
Funding Amount
$458,318.00
Summary
Quantum sensing of magnetism in two dimensions. This project aims to use innovative quantum sensing technologies to investigate the novel emerging field of two-dimensional magnetism; imaging both static and dynamic forms of 2D magnetism. This project expects to generate new knowledge about magnetic van der Waals materials and their potential application to ultra-thin electronic and spintronic devices. Expected outcomes of this project are a deeper understanding of the formation and modulation of ....Quantum sensing of magnetism in two dimensions. This project aims to use innovative quantum sensing technologies to investigate the novel emerging field of two-dimensional magnetism; imaging both static and dynamic forms of 2D magnetism. This project expects to generate new knowledge about magnetic van der Waals materials and their potential application to ultra-thin electronic and spintronic devices. Expected outcomes of this project are a deeper understanding of the formation and modulation of magnetic order in 2D, new fabrication methods for deliberate domain wall formation, production of near-zero energy gap spin-waves, and new encapsulation methods for ultra-stable 2D materials. This should provide significant benefits towards fundamental physics and future device engineering. Read moreRead less
Electron Emission from Diamond. Israel is emerging as an international hub of technology with one of the highest rates of R&D in the world. This collaborative project will access one of the world leading experts in diamond science and technology, Professor Alon Hoffman, to exploit the remarkable properties of diamond for a new generation of detectors and devices. Success in this project can lay the groundwork for tapping into the successful record of advanced technologies and venture capital fun ....Electron Emission from Diamond. Israel is emerging as an international hub of technology with one of the highest rates of R&D in the world. This collaborative project will access one of the world leading experts in diamond science and technology, Professor Alon Hoffman, to exploit the remarkable properties of diamond for a new generation of detectors and devices. Success in this project can lay the groundwork for tapping into the successful record of advanced technologies and venture capital funding that abound in Israel today. Read moreRead less
Precise atomic-scale structure determination in thick nanostructures. This project aims to tackle a great challenge of atomic-scale characterisation: quantitative structure determination. Powerful new electron microscopes offer a window into the atomic world, but complex electron multiple scattering has limited reliable structure determination to ultrathin materials. This project expects to overcome this barrier. Anticipated outcomes include methods that use the latest detector technology to det ....Precise atomic-scale structure determination in thick nanostructures. This project aims to tackle a great challenge of atomic-scale characterisation: quantitative structure determination. Powerful new electron microscopes offer a window into the atomic world, but complex electron multiple scattering has limited reliable structure determination to ultrathin materials. This project expects to overcome this barrier. Anticipated outcomes include methods that use the latest detector technology to determine structure and interatomic bonding in much thicker nanostructures than hitherto possible. This should benefit academic and industrial researchers by giving them new tools to understand and design high-performance materials for applications ranging from catalysis to energy storage to next-generation electronics.Read moreRead less