Risk Stratification Of Older People In Hospital: Validation And Influence On Clinical Decision Making
Funder
National Health and Medical Research Council
Funding Amount
$291,067.00
Summary
Older people in hospital are at high risk of adverse outcomes, a vulnerability commonly referred to as frailty. In community-dwelling older people, frailty status can be measured precisely with a Frailty Index score. This research aims to develop a Frailty Index from a standardised comprehensive geriatric assessment instrument used in the routine care of many patients in hospital. This would assist clinicians to identify vulnerable older inpatients, improving their care in the acute setting.
Designing Radiation-Tolerant Reconfigurable Systems for Space. The processing speed, cost and flexibility requirements of future satellite-based applications cannot be satisfied with conventional radiation-hardened processors or custom integrated circuits. This project aims to develop key technology to enable off-the-shelf hardware to be customised for this use without compromising reliability. The project aims to develop the design methods needed to implement a given set of satellite applicatio ....Designing Radiation-Tolerant Reconfigurable Systems for Space. The processing speed, cost and flexibility requirements of future satellite-based applications cannot be satisfied with conventional radiation-hardened processors or custom integrated circuits. This project aims to develop key technology to enable off-the-shelf hardware to be customised for this use without compromising reliability. The project aims to develop the design methods needed to implement a given set of satellite applications on a processing platform composed of application-specific soft processors and accelerator circuits hosted on conventional reconfigurable logic devices. Crucially, the solution architecture is expected to be sufficiently hardened against radiation-induced errors while meeting performance and circuit area constraints.Read moreRead less
Development And Validation Of A Latent Tuberculosis Diagnostic
Funder
National Health and Medical Research Council
Funding Amount
$534,865.00
Summary
Globally, tuberculosis is a leading cause of death with 9.6 million new diagnoses in 2014. The diagnosis of latent TB infection is important, but is difficult to make because current assays are suboptimal. We have developed a very simple assay which detects responses to TB antigens by co-expression of two surface markers expressed by CD4+ T cells. We propose to develop this into a highly standardised kit for the diagnosis of TB with our commercial partner Cytognos.
Validation Of A Multiplexed Blood Based Screening Assay For The Diagnosis Of Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$556,712.00
Summary
Colorectal cancer (CRC) is the second most common cancer in Australia with poor patient outcome due to late detection of the disease. We have developed a simple blood based test that can diagnose individuals with CRC at an early stage when the chance of cure is greater than 80%.
Evaluation Of SCID-I In The Diagnosis Of Mental Disorders In Indigenous Australians
Funder
National Health and Medical Research Council
Funding Amount
$988,007.00
Summary
Current estimates of mental disease among Indigenous Australians are inadequate. This research will examine the use of a structured interview tool that is promoted globally for diagnosing mental disorders, and then use the tool to quantify the burden of mental illness among Indigenous Australians. The findings will provide accurate estimates of occurrence of mental disorders, thereby help inform policy making and planning of services for Indigenous Australians.
Metamorphic slices and their applications in fault localization. The main purpose of this project is to enhance the quality of software. The expected outcomes include the delivery of new cost-effective methods to debug software, and the extension of current debugging methods to be applicable in wider contexts.
Cost-effective use of assertions in the verification and validation of distributed and real-time systems. The project will reinforce Australia as a world leader in empirical software engineering and software verification and validation research, thus building on Australia's strengths in ICT research and innovation. Through the involvement of a local software verification and validation company and through industrial case studies, this project will also improve the software verification and valid ....Cost-effective use of assertions in the verification and validation of distributed and real-time systems. The project will reinforce Australia as a world leader in empirical software engineering and software verification and validation research, thus building on Australia's strengths in ICT research and innovation. Through the involvement of a local software verification and validation company and through industrial case studies, this project will also improve the software verification and validation capabilities of local industry, allow them to save software development costs, and improve the quality of the software produced.Read moreRead less
Integration of Metamorphic Testing and Model Checking. This project proposes an innovative approach of integrating metamorphic testing and model checking. Its main outcome will be to deliver a comprehensive testing method that will help to reduce errors and costs in software development and consequently to improve the quality of software systems. Since software is pervasive and ubiquitous, our results will improve the nation's software productivity and quality. Thus, our results will help in ra ....Integration of Metamorphic Testing and Model Checking. This project proposes an innovative approach of integrating metamorphic testing and model checking. Its main outcome will be to deliver a comprehensive testing method that will help to reduce errors and costs in software development and consequently to improve the quality of software systems. Since software is pervasive and ubiquitous, our results will improve the nation's software productivity and quality. Thus, our results will help in raising our nation's competitive advantage towards the goal of becoming a leading nation in the software industry among Asia-Pacific countries. Furthermore, this collaboration will help young Australian researchers to link to the Chinese Academy of Sciences, a leading-edge international research institute.Read moreRead less
Metamorphic Testing: An In-Depth Study to Enhance the Failure-Detection Capability of Software Testing Without an Oracle. Nowadays, software is pervasive and ubiquitous. It plays a significant role in the daily lives of all kinds of people. The Australian software industry has bloomed in recent years. Our research results will improve the cost-effectiveness of software development, thereby upgrading the nation's software productivity and quality. These factors are conducive to the export of soft ....Metamorphic Testing: An In-Depth Study to Enhance the Failure-Detection Capability of Software Testing Without an Oracle. Nowadays, software is pervasive and ubiquitous. It plays a significant role in the daily lives of all kinds of people. The Australian software industry has bloomed in recent years. Our research results will improve the cost-effectiveness of software development, thereby upgrading the nation's software productivity and quality. These factors are conducive to the export of software produced by Australians and helpful in raising our nation's competitive advantage towards the goal of becoming a leading nation in the software industry among Asia-Pacific countries.Read moreRead less
A Comprehensive Testing Methodology for Embedded Software. Embedded systems are a bedrock technology for many high-technology industries. They are used in many safety-critical situations, such as medical devices and car control systems, amongst hundreds of other applications. Unfortunately, current practice still sometimes results in disastrous mistakes remaining undetected, leading to multi-million dollar losses and in some cases even deaths. Improved testing methods for these systems offer ....A Comprehensive Testing Methodology for Embedded Software. Embedded systems are a bedrock technology for many high-technology industries. They are used in many safety-critical situations, such as medical devices and car control systems, amongst hundreds of other applications. Unfortunately, current practice still sometimes results in disastrous mistakes remaining undetected, leading to multi-million dollar losses and in some cases even deaths. Improved testing methods for these systems offer the potential of reducing such catastrophic losses. Improved embedded system testing techniques can offer Australia a competitive advantage in this strategically important industry. We will work to distribute our results to the Australian embedded systems community.Read moreRead less