Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100197
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
National magnetochemical facility. New magnetic materials of the molecular or biological types are quite different to traditional metal oxide magnets widely used, for example, in recording devices. They are very important from the perspective of understanding fundamental properties at low temperatures, in high magnetic fields, or when irradiated by light, but they are also showing promise in a range of applications, such as memory devices and smart cards and in the new area of spintronics and m ....National magnetochemical facility. New magnetic materials of the molecular or biological types are quite different to traditional metal oxide magnets widely used, for example, in recording devices. They are very important from the perspective of understanding fundamental properties at low temperatures, in high magnetic fields, or when irradiated by light, but they are also showing promise in a range of applications, such as memory devices and smart cards and in the new area of spintronics and molecular computers. The magnetochemical projects described here, that require the new equipment being sought, are fundamental in nature but will provide the underpinning of future nanomagnetic materials.Read moreRead less
Redox initiated chemistry of hydrogenase H-cluster model compounds: Biologically inspired hydrogen activation catalysts? High efficiency, low temperature, cheap hydrogen activation catalysts suitable for fuel cell applications would provide the basis for the development of environmentally benign technologies suitable for transportation and some power applications. Hydrogenase enzymes are high efficiency, low temperature, hydrogen activation catalysts and the active site of the all-iron version ....Redox initiated chemistry of hydrogenase H-cluster model compounds: Biologically inspired hydrogen activation catalysts? High efficiency, low temperature, cheap hydrogen activation catalysts suitable for fuel cell applications would provide the basis for the development of environmentally benign technologies suitable for transportation and some power applications. Hydrogenase enzymes are high efficiency, low temperature, hydrogen activation catalysts and the active site of the all-iron version of the enzyme has recently been revealed to be a remarkable, weakly protein bound, iron-sulfur-carbonyl-cyanide complex. Research into the reactions of redox activated abiological model compounds will provide insights into the molecular basis of the enzymatic reaction, potentially leading to the discovery of highly efficient, biologically inspired hydrogen activation catalysts.Read moreRead less
Nanosized peptide nucleic acid - metal complex hybrids as catalysts for the cleavage of phosphate ester bonds in biological molecules. The information from Human Genome Project is being used to generate molecules with a variety of therapeutic and diagnostic applications. The capability to design, synthesise and manipulate functional molecules that mimic biological processes will underpin many emerging applications. In this project, macrocyclic metal complexes that catalyse the cleavage of phosph ....Nanosized peptide nucleic acid - metal complex hybrids as catalysts for the cleavage of phosphate ester bonds in biological molecules. The information from Human Genome Project is being used to generate molecules with a variety of therapeutic and diagnostic applications. The capability to design, synthesise and manipulate functional molecules that mimic biological processes will underpin many emerging applications. In this project, macrocyclic metal complexes that catalyse the cleavage of phosphate ester bonds in biological molecules will be developed. Active complexes will be incorporated into nanosized peptide nucleic acid (PNA) - metal complex hybrids and applied as artificial enzymes in the sequence specific cleavage of RNA and DNA. Novel applications of these ?artificial enzymes? in biotechnology are anticipated.Read moreRead less
Bio-inspired Catalysts for Water Oxidation. Successful completion of the project will result in the development of devices that utilise redox active manganese clusters to catalyse the oxidation of water. This achievement would place us at the forefront of international efforts to develop devices that can split water into hydrogen and oxygen, an endeavour which has the potential to solve pressing energy demands. As an added benefit, these devices can be adapted for the purposes of carrying out th ....Bio-inspired Catalysts for Water Oxidation. Successful completion of the project will result in the development of devices that utilise redox active manganese clusters to catalyse the oxidation of water. This achievement would place us at the forefront of international efforts to develop devices that can split water into hydrogen and oxygen, an endeavour which has the potential to solve pressing energy demands. As an added benefit, these devices can be adapted for the purposes of carrying out the catalytic oxidation of organic substrates, for which a variety of industrial and environmental applications can be envisaged.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882977
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Enhanced NMR Research, Characterisation and Analysis Facility. Studying molecular species is at the heart of chemistry and biochemistry and fundamental to improving our understanding of molecular mechanisms and interactions. This becomes important for elucidating aspects of biological function, medicinal and pharmaceutical chemistry, materials science and synthetic methodology, which all underpin health and technology advances in Australia. The infrastructure will support projects involving fun ....Enhanced NMR Research, Characterisation and Analysis Facility. Studying molecular species is at the heart of chemistry and biochemistry and fundamental to improving our understanding of molecular mechanisms and interactions. This becomes important for elucidating aspects of biological function, medicinal and pharmaceutical chemistry, materials science and synthetic methodology, which all underpin health and technology advances in Australia. The infrastructure will support projects involving fundamental and strategic research spanning nanotechnology and the biological and materials sciences to industry-oriented projects.Read moreRead less
Integration of Electrochemistry and Green Chemistry: A Roadmap for Scientific Innovation. Electrochemistry represents an enabling science in physical, chemical and life sciences. It plays a key role in fundamental studies and in Australia's industrial capacity to exploit emerging technologies. Research conducted synergistically within the ARC Centre for Green Chemistry would enable the Monash Electrochemistry Group to develop and exploit new concepts. In the national interest, the Fellowship ....Integration of Electrochemistry and Green Chemistry: A Roadmap for Scientific Innovation. Electrochemistry represents an enabling science in physical, chemical and life sciences. It plays a key role in fundamental studies and in Australia's industrial capacity to exploit emerging technologies. Research conducted synergistically within the ARC Centre for Green Chemistry would enable the Monash Electrochemistry Group to develop and exploit new concepts. In the national interest, the Fellowship would: facilitate global participation in cutting-edge science derived from electrochemical and green chemical concepts; provide commercial opportunities for new and mature chemical industries; expand postgraduate training; and promote technology exchange with Australian and international leading-edge research organisations.Read moreRead less
Large amplitude Fourier transformed voltammetry: paths towards more efficient data evaluation strategies, enhanced insights and innovation in dynamic electrochemistry. Electrochemistry represents an enabling discipline in many branches of science. The aim of this research is to integrate the collective skills of an international consortium of experts in electrochemistry, electrical engineering, computing and mathematics in order to implement a blueprint proposed for innovation in electrochemic ....Large amplitude Fourier transformed voltammetry: paths towards more efficient data evaluation strategies, enhanced insights and innovation in dynamic electrochemistry. Electrochemistry represents an enabling discipline in many branches of science. The aim of this research is to integrate the collective skills of an international consortium of experts in electrochemistry, electrical engineering, computing and mathematics in order to implement a blueprint proposed for innovation in electrochemical science. In the national interest, the project will facilitate global participation in cutting-edge science derived from electrochemical concepts, provide commercial opportunities in the area of scientific instrumentation and promote technology exchange with Australian and international leading-edge research organizations.Read moreRead less
A blueprint for an intelligent instrumental, theoretical and experimental unification of a myriad of voltammetric and related electrochemical techniques. Electrochemistry is a prominent discipline in many areas of fundamental and applied science (for example, electron transfer reactions, corrosion, sensors, photovoltaics). The aim of the research proposal is to utilise skills available at Monash University and those of a national and international consortium of experts in electrochemistry, elec ....A blueprint for an intelligent instrumental, theoretical and experimental unification of a myriad of voltammetric and related electrochemical techniques. Electrochemistry is a prominent discipline in many areas of fundamental and applied science (for example, electron transfer reactions, corrosion, sensors, photovoltaics). The aim of the research proposal is to utilise skills available at Monash University and those of a national and international consortium of experts in electrochemistry, electrical engineering, computing and mathematics to introduce a new integrated instrumental, theoretical and experimental concept that will provide a blueprint for innovation in electrochemical science. An expected outcome is that important advances relevant to Australian Industry will be achieved in the area of scientific instrumentation and in modern applications of electrochemistry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775725
Funder
Australian Research Council
Funding Amount
$465,000.00
Summary
Molecular separation and characterisation - A facility for advanced mass spectroscopy and chromatography. Characterising molecular composition is a basic need for the progress of many sciences. It is used to examine traditional and modern medicinal chemistry, bio-active peptides, molecular modulation of chemical properties, markers of disease and system status, and can also be used to elucidate molecular mechanisms and interactions in a system. This can only be achieved through precise measureme ....Molecular separation and characterisation - A facility for advanced mass spectroscopy and chromatography. Characterising molecular composition is a basic need for the progress of many sciences. It is used to examine traditional and modern medicinal chemistry, bio-active peptides, molecular modulation of chemical properties, markers of disease and system status, and can also be used to elucidate molecular mechanisms and interactions in a system. This can only be achieved through precise measurement using the frontier technologies described in this grant. This proposal ensures international competitiveness on a broad front, and supports highest level research training and bio/chemical/medical research in several priority research areas. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560685
Funder
Australian Research Council
Funding Amount
$451,000.00
Summary
Scanning Probe Microscopy for Bioelectrochemistry. New methods to study the fundamental properties of biological samples, in particular proteins, are continuing to advance and impact on society. We will establish a leading edge facility for high-resolution imaging of biomolecules with redox functions. This will enable the continued development of new enzyme based diagnostic tests by understanding the dynamic nature of coupled electron and molecular interactions with redox enzymes in solution. Th ....Scanning Probe Microscopy for Bioelectrochemistry. New methods to study the fundamental properties of biological samples, in particular proteins, are continuing to advance and impact on society. We will establish a leading edge facility for high-resolution imaging of biomolecules with redox functions. This will enable the continued development of new enzyme based diagnostic tests by understanding the dynamic nature of coupled electron and molecular interactions with redox enzymes in solution. The bioelectrochemical imaging facility will be unique in Australia and establish an important cross-disciplinary approach within the international community.Read moreRead less