Industrial-strength X-ray Phase Tomography. The unique 3D imaging capability provided as a result of this project will have application to advanced manufacturing as a non-destructive evaluation for materials and micro-components. For instance, the internal structure of aerogels, porous light metals, polymers and carbon fibre based materials can all be imaged at the microscale. Similar benefits flow in health sciences where organic processes can be observed in place and where, for instance, small ....Industrial-strength X-ray Phase Tomography. The unique 3D imaging capability provided as a result of this project will have application to advanced manufacturing as a non-destructive evaluation for materials and micro-components. For instance, the internal structure of aerogels, porous light metals, polymers and carbon fibre based materials can all be imaged at the microscale. Similar benefits flow in health sciences where organic processes can be observed in place and where, for instance, small animals used in research and clinical testing can be inspected internally without having to destroy them, thus allowing for repeated measurements.Read moreRead less
Elucidating structure and function of activation-associated secreted proteins (ASPs) in blood-feeding hookworms – toward new methods of control. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links betwee ....Elucidating structure and function of activation-associated secreted proteins (ASPs) in blood-feeding hookworms – toward new methods of control. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by promoting collaborative research, resulting in a more efficient use of resources in a national and international context; (4) to enhance the skills-base in biology and biotechnology; (5) to substantially increase global visibility through quality research, leading to an increased investment in Australian science.Read moreRead less
Mitogenomics using a massively parallel reactor platform - from barcoding to diagnostic tools for pathogens of major socioeconomic importance. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between ....Mitogenomics using a massively parallel reactor platform - from barcoding to diagnostic tools for pathogens of major socioeconomic importance. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by promoting collaborative research, resulting in a more efficient use of resources in a national and international context; (4) to enhance the skills-base in biology and biotechnology; (5) to substantially increase global visibility through quality research, leading to an increased investment in Australian science.
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ARC Centre of Excellence - Coherent X-ray Science. The twenty first century is said to be the century of biology. And there is no doubt that the development of our understanding of biological system is continuing at a massive rate. However as our understanding deepens, we need to draw on the whole range of scientific disciplines to proceed. This Centre draws together a multidisciplinary team of world-leading scientists to address one the key questions in modern biology, the structure of a membra ....ARC Centre of Excellence - Coherent X-ray Science. The twenty first century is said to be the century of biology. And there is no doubt that the development of our understanding of biological system is continuing at a massive rate. However as our understanding deepens, we need to draw on the whole range of scientific disciplines to proceed. This Centre draws together a multidisciplinary team of world-leading scientists to address one the key questions in modern biology, the structure of a membrane protein. We will develop techniques based on the latest developments in theoretical physics & chemistry, imaging, biology and technology - including the new Australian Synchrotron - to create new approaches to structural biology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560725
Funder
Australian Research Council
Funding Amount
$127,042.00
Summary
Enhancing the Monash-VIEPS Stable Isotope Facility. This proposal is to enhance the Monash-Victorian Institute of Earth and Planetary Sciences (VIEPS) Stable Isotope Facility to expand our capacity for state-of-the-art research in hydrogeology, hydrology, aqueous chemistry, modern and palaeoclimatology, sedimentology, geochemistry, economic geology, and biological sciences. This facility will then have an analytical capability that is at least the equal of those elsewhere in Australia and which ....Enhancing the Monash-VIEPS Stable Isotope Facility. This proposal is to enhance the Monash-Victorian Institute of Earth and Planetary Sciences (VIEPS) Stable Isotope Facility to expand our capacity for state-of-the-art research in hydrogeology, hydrology, aqueous chemistry, modern and palaeoclimatology, sedimentology, geochemistry, economic geology, and biological sciences. This facility will then have an analytical capability that is at least the equal of those elsewhere in Australia and which will maintain our position as a World Class stable isotope research facility. The enhanced facility will permit new research to be carried out that will lead to new collaborations both within the traditional Earth Sciences and across disciplines.Read moreRead less
New and computationally feasible methods of constructing efficient and exact confidence limits from count data. Biological and health science data is commonly in the form of counts. The statistical analysis of such data should be (a) efficient i.e. it should not, in effect, throw away valuable data, (b) exact i.e. it should have precisely known statistical properties and (c) computationally feasible. Kabaila and Lloyd (1997-2001) have proposed and analysed a radically new method of confidence li ....New and computationally feasible methods of constructing efficient and exact confidence limits from count data. Biological and health science data is commonly in the form of counts. The statistical analysis of such data should be (a) efficient i.e. it should not, in effect, throw away valuable data, (b) exact i.e. it should have precisely known statistical properties and (c) computationally feasible. Kabaila and Lloyd (1997-2001) have proposed and analysed a radically new method of confidence limit construction which, for the first time, possesses all of these requirements. The purpose of the project is to establish further theoretical support for the new method, to develop efficient computational algorithms and to write easy-to-use computer programs for its practical use.Read moreRead less
Megafauna and mega-extinction: assessing palaeocommunity change using dental complexity and shape analyses. This research will address an important issue of national interest - the causes of the extinction of the Australian megafauna. By furthering research on the causes of this historic event, valuable insights will be gained into possible causes of current extinction events and the future impact of climate change. It will bring to Australia new technologies and methods developed overseas by an ....Megafauna and mega-extinction: assessing palaeocommunity change using dental complexity and shape analyses. This research will address an important issue of national interest - the causes of the extinction of the Australian megafauna. By furthering research on the causes of this historic event, valuable insights will be gained into possible causes of current extinction events and the future impact of climate change. It will bring to Australia new technologies and methods developed overseas by an Australian researcher, and put Australia at the forefront of several areas of research including 3D scanning and analysis. This project will form part of an international collaboration called the MorphoBrowser, an exciting advance in the study of biological diversity. This will help maintain Australia as a pre-eminent country for palaeontology research.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883036
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Integrated Vibrational Spectroscopic Mapping for Archeological, Biological, Geological, Materials, and Medical Research. The expected benefits that will arise will include: green chemical processes with improved environmental and economic impacts; improved treatments and diagnoses of diseases; understanding of fundamental geological processes; identification of the earliest forms; studies of archaeological artefacts; evolution of life on Earth; the design of improved dental materials. Ultimatel ....Integrated Vibrational Spectroscopic Mapping for Archeological, Biological, Geological, Materials, and Medical Research. The expected benefits that will arise will include: green chemical processes with improved environmental and economic impacts; improved treatments and diagnoses of diseases; understanding of fundamental geological processes; identification of the earliest forms; studies of archaeological artefacts; evolution of life on Earth; the design of improved dental materials. Ultimately, this research will include economic and social benefits in; industrial processes; the mining industry; medicine; and dentistry. An understanding of the origin and early evolution of life on Earth also has many social implications.Read moreRead less
Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications. The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surfa ....Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications. The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surface coatings, films and advanced particles, leading to significant outcomes in diverse areas, including drug delivery, biomaterial implants and biocatalysis. The project will contribute to the development of a robust Australian nanotechnology industry, with the advanced materials developed expected to have health benefits for Australian citizens.Read moreRead less
Building Molecularly Engineered Polymer Nanomaterials. The development of new technologies at the interface between nano- and biotechnology promises to revolutionise healthcare and medicine. This research program will involve the design and synthesis of responsive and programmable polymers and their assembly to form next-generation, engineered materials. The nanomaterials prepared are expected to lead to the development of techniques that enable new types of minimally invasive diagnostics and th ....Building Molecularly Engineered Polymer Nanomaterials. The development of new technologies at the interface between nano- and biotechnology promises to revolutionise healthcare and medicine. This research program will involve the design and synthesis of responsive and programmable polymers and their assembly to form next-generation, engineered materials. The nanomaterials prepared are expected to lead to the development of techniques that enable new types of minimally invasive diagnostics and therapeutics as well as smaller devices. The interdisciplinary research program will cement Australia's position as a leading country in nanobiotechnology research and development.Read moreRead less