Hop (Humulus lupulus L.) flavoromics for distinctive beer. Hop is the spice of beer, as it provides unique flavour chemicals imparting taste (bitterness) and aroma. With the worldwide rise of craft beer, there is international demand for differentiated beer. The flavour potential of hop has not been fully explored, and the genetic basis of hop chemistry is poorly understood. This project aims to gather flavoromic data through modern analytical chemistry, genomics, molecular genetics and brewing ....Hop (Humulus lupulus L.) flavoromics for distinctive beer. Hop is the spice of beer, as it provides unique flavour chemicals imparting taste (bitterness) and aroma. With the worldwide rise of craft beer, there is international demand for differentiated beer. The flavour potential of hop has not been fully explored, and the genetic basis of hop chemistry is poorly understood. This project aims to gather flavoromic data through modern analytical chemistry, genomics, molecular genetics and brewing in order to better understand the genetic basis of hop chemistry which affects the entire value chain: from hop farm to consumers' experience of beer. The overarching aim of this project is to offer smart breeding strategies leading to novel flavours (taste and aroma) for existing and emerging breweries.Read moreRead less
Probing the Tasmanian Devil Serum Proteome for Preclinical Diagnosis of Devil Facial Tumour Disease. The Tasmanian Devil (Sarcophilus harrisii) is a carnivorous marsupial endemic to the island state of Tasmania, and is found all over the state. Over the past decade, a dramatic decline has occurred in the Devil population in association with the emergence of Devil Facial Tumour Disease (DFTD). This project aims to develop a preclinical diagnostic test for DFTD that will provide vital information ....Probing the Tasmanian Devil Serum Proteome for Preclinical Diagnosis of Devil Facial Tumour Disease. The Tasmanian Devil (Sarcophilus harrisii) is a carnivorous marsupial endemic to the island state of Tasmania, and is found all over the state. Over the past decade, a dramatic decline has occurred in the Devil population in association with the emergence of Devil Facial Tumour Disease (DFTD). This project aims to develop a preclinical diagnostic test for DFTD that will provide vital information for use in developing management strategies to ensure the ongoing survival of the Tasmanian Devil. The benefit to Australia in performing this research rests in the new technology that will be developed and the application of this technology to key areas of national and international significance.Read moreRead less
Hatchery production of rock lobster seedstock for aquaculture and enhancement with emphasis on ozonation of culture water to reduce disease. The strong and growing worldwide demand for a range of lobster products cannot be fulfilled by existing wild fisheries. Only the sustainable production of lobsters using hatchery seedstock will satisfy the needs of aquaculture and the possibility of enhancing and reseeding the fishery. Lobster aquaculture will provide a new high-value industry for coastal r ....Hatchery production of rock lobster seedstock for aquaculture and enhancement with emphasis on ozonation of culture water to reduce disease. The strong and growing worldwide demand for a range of lobster products cannot be fulfilled by existing wild fisheries. Only the sustainable production of lobsters using hatchery seedstock will satisfy the needs of aquaculture and the possibility of enhancing and reseeding the fishery. Lobster aquaculture will provide a new high-value industry for coastal rural Australia, especially in areas with existing fishing and aquaculture enterprises. This project will develop new technologies to address the challenging target of producing commercial quantities of juvenile lobsters for aquaculture and enhancement.Read moreRead less
Non-discriminatory, universal and sensitive detection technologies for fluid based separation techniques in the pharmaceutical industry. The proposed research is focused on the specific needs of Australian and global pharmaceutical industries, and addresses a problem which is becoming increasingly significant with new classes of pharmaceuticals. Successful achievement of the goals of the project will result in major savings of cost and time during drug development and will lead to the productio ....Non-discriminatory, universal and sensitive detection technologies for fluid based separation techniques in the pharmaceutical industry. The proposed research is focused on the specific needs of Australian and global pharmaceutical industries, and addresses a problem which is becoming increasingly significant with new classes of pharmaceuticals. Successful achievement of the goals of the project will result in major savings of cost and time during drug development and will lead to the production of safer drugs. The project will expand collaboration between Australia researchers and the world's largest pharmaceutical company. Specialised training will be provided to both postdoctoral and postgraduate researchers, positioning them to make strong contributions to Australia's growing pharmaceutical industry.Read moreRead less
Special Research Initiatives - Grant ID: SR0354560
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
AUSTRALIAN RESEARCH NETWORK IN ANALYTICAL SCIENCE (ARNAS). The initiative will provide the foundations for the establishment of an Australian Research Network in Analytical Science (ARNAS), which will bring together fundamental researchers and practitioners working in quantitative chemical analysis and related areas. ARNAS will provide national coordination of research in analytical science, coverage of the newest developments, pooling of expertise and research facilities and resources, and rap ....AUSTRALIAN RESEARCH NETWORK IN ANALYTICAL SCIENCE (ARNAS). The initiative will provide the foundations for the establishment of an Australian Research Network in Analytical Science (ARNAS), which will bring together fundamental researchers and practitioners working in quantitative chemical analysis and related areas. ARNAS will provide national coordination of research in analytical science, coverage of the newest developments, pooling of expertise and research facilities and resources, and rapid dissemination of outcomes. ARNAS will significantly advance the national research agenda for analytical science by improving awareness of research activities and expertise, providing enhanced education and opportunities for the next generation of analytical scientists, and by stimulating new international collaborations.Read moreRead less
Self-assembled nanolayers of functionalised latexes as selective and adaptable nano-stationary phases in separation science. A new approach is proposed for the design and synthesis of functionalised ion-exchange stationary phases for analytical nano-separation methods. Desired charged functional groups are first affixed chemically onto nanometre sized latex particles and these particles are then self-assembled mechanically as monoloayer coatings onto a suitable supporting template such as fused ....Self-assembled nanolayers of functionalised latexes as selective and adaptable nano-stationary phases in separation science. A new approach is proposed for the design and synthesis of functionalised ion-exchange stationary phases for analytical nano-separation methods. Desired charged functional groups are first affixed chemically onto nanometre sized latex particles and these particles are then self-assembled mechanically as monoloayer coatings onto a suitable supporting template such as fused silica, monolithic silica or polymer beds, microfibres or microtubes, and channels in microchips. The resultant coated surface then acts as a highly efficient ion-exchange stationary phase which will be used in a wide range of separation technologies including ion chromatography, capillary electrophoresis, capillary electrochromatography and solid-phase microextraction.Read moreRead less
Separation science based on nanoparticle-coated monolithic scaffold stationary phases. The proposed project will generate highly significant, fundamental advances in separation science by developing new stationary phases and separation technologies suitable for the analysis of very complex samples which cannot be addressed by current methods. These technologies will be applied in a wide range of areas of national importance including pre-and post-blast identification of explosives in counter-ter ....Separation science based on nanoparticle-coated monolithic scaffold stationary phases. The proposed project will generate highly significant, fundamental advances in separation science by developing new stationary phases and separation technologies suitable for the analysis of very complex samples which cannot be addressed by current methods. These technologies will be applied in a wide range of areas of national importance including pre-and post-blast identification of explosives in counter-terrorism applications; environmental, clinical, and forensic analysis; energy generation and foods. The project will also lead to very significant new intellectual property having extremely high commercial potential worldwide, and thereby generates the promise of considerable direct financial returns to Australia.Read moreRead less
Integrated microfluidic device for the direct analysis of drugs and metabolites in biological fluids. Due to the way in which multiple processes are integrated in a micro Total Analysis System (µTAS), they offer substantial advantages over current technology, in terms of speed, cost of analysis, portability and operator simplicity and safety. This has considerable potential benefit for Australia, specifically for the remote and rural analysis of drugs and metabolites in biological fluids such a ....Integrated microfluidic device for the direct analysis of drugs and metabolites in biological fluids. Due to the way in which multiple processes are integrated in a micro Total Analysis System (µTAS), they offer substantial advantages over current technology, in terms of speed, cost of analysis, portability and operator simplicity and safety. This has considerable potential benefit for Australia, specifically for the remote and rural analysis of drugs and metabolites in biological fluids such as blood, serum, urine and saliva. These devices will have application for point-of-care testing in therapeutic drug monitoring, which will improve medical treatment and the patient's quality of life, as well as for on-site analysis in forensics for the rapid determination of illicit drugs and performance enhancing substances in our elite athletes.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989491
Funder
Australian Research Council
Funding Amount
$172,025.00
Summary
Multi-Purpose Mass Spectrometry Facility. The Australian Centre for Research on Separation Science (ACROSS) has been established using focused research themes to provide both fundamental and applied research outcomes in separation science. The requested Time of Flight Mass Spectrometer (TOFMS) will be utilised extensively by a large team of researchers working across the broad areas of analytical chemistry, pharmaceutical science, materials science, biochemistry, microfluidics, industrial chemi ....Multi-Purpose Mass Spectrometry Facility. The Australian Centre for Research on Separation Science (ACROSS) has been established using focused research themes to provide both fundamental and applied research outcomes in separation science. The requested Time of Flight Mass Spectrometer (TOFMS) will be utilised extensively by a large team of researchers working across the broad areas of analytical chemistry, pharmaceutical science, materials science, biochemistry, microfluidics, industrial chemistry and hydrometallurgy, aquaculture, forensic analysis, Antarctic studies, and environmental monitoring. This will directly support our work falling under National Research Priorities 1 An Environmentally Sustainable Australia, 2 Promoting and Maintaining Good Health, 3 Frontier Technologies for Building and Transforming Australian Industries, and 4 Safeguarding Australia.Read moreRead less
Synthesis, characterisation and evaluation of novel ion-exchange polymer monolithic stationary phases for separation science. This project will provide highly significant, fundamental advances in separation science by accelerating the design and development of new stationary phases and separation technologies suitable for the analysis of very complex samples. The project will lead to very significant new intellectual property having extremely high commercial potential worldwide, and therefore t ....Synthesis, characterisation and evaluation of novel ion-exchange polymer monolithic stationary phases for separation science. This project will provide highly significant, fundamental advances in separation science by accelerating the design and development of new stationary phases and separation technologies suitable for the analysis of very complex samples. The project will lead to very significant new intellectual property having extremely high commercial potential worldwide, and therefore the project has potential for considerable direct financial returns to Australia. The new technologies will be applied in a wide range of areas of national importance including pre-and post-blast identification of explosives in counter-terrorism applications; environmental, clinical, and forensic analysis; energy generation and foods. Read moreRead less