Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable mode ....Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable modelled small-area estimates to be released without compromising confidentiality. The expected outcomes include new statistical knowledge and new insights into cancer. The results will benefit the many disciplines, managers and policy makers that make decisions based on geographic data mapped over space and time. Read moreRead less
Bayesian methodology for analysis of genome data with focus on the livestock industry. The aim is to develop statistical methods for the design and analysis of genome data with focus on the special needs of the livestock industry. This will significantly contribute to profitability, quality, genetic improvement and genetic knowledge in a key national industry, improve Australia's international and national profile in the key research area of bioinformatics, and encourage optimisation of current ....Bayesian methodology for analysis of genome data with focus on the livestock industry. The aim is to develop statistical methods for the design and analysis of genome data with focus on the special needs of the livestock industry. This will significantly contribute to profitability, quality, genetic improvement and genetic knowledge in a key national industry, improve Australia's international and national profile in the key research area of bioinformatics, and encourage optimisation of current information. Outcomes include a toolkit of applicable statistical methods, statistically valid algorithms, marketable methods for gene discovery, technology transfer, training and publications.Read moreRead less
Bayesian statistical methods for enhancing evidence-based practice in Australia's hospitals. This project addresses Australia's national research priority of Promoting and Maintaining Good Health with the goal of Preventative Healthcare. Through enhanced capability in combining information from diverse sources for improved evidence-based decisions and true sharing of university and medical expertise, the project will enhance Australia's medical research and practice, align professional and comm ....Bayesian statistical methods for enhancing evidence-based practice in Australia's hospitals. This project addresses Australia's national research priority of Promoting and Maintaining Good Health with the goal of Preventative Healthcare. Through enhanced capability in combining information from diverse sources for improved evidence-based decisions and true sharing of university and medical expertise, the project will enhance Australia's medical research and practice, align professional and community expectations, utilise local medical information, and address national demands for quality science underpinning health decisions.
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Making the Most of Database Information in Patient-Based Decision-Making - A Bayesian Approach. This project addresses Australia's national research priority of Promoting and Maintaining Good Health and will lead to immediate improvement in health outcomes through optimising patient outcomes in Australian hospitals; cross-disciplinary and cross-hospital communication. Through enhanced capability in combining information from diverse sources the project will enhance Australia's medical research a ....Making the Most of Database Information in Patient-Based Decision-Making - A Bayesian Approach. This project addresses Australia's national research priority of Promoting and Maintaining Good Health and will lead to immediate improvement in health outcomes through optimising patient outcomes in Australian hospitals; cross-disciplinary and cross-hospital communication. Through enhanced capability in combining information from diverse sources the project will enhance Australia's medical research and practice, align professional and community expectations, utilise increased amounts of local medical information, and address national demands for quality science underpinning health decisions.Read moreRead less
Innovative Bayesian statistics for enhanced decision making for pharmaceutical drug development. This project addresses Australia's national research priority of Promoting and Maintaining Good Health, and will lead to improvements in health outcomes by patients accessing new drugs sooner, enhancing research, and reducing the cost of health care. Decision making in early stages of drug development will be improved by using novel statistical methods, which could also be applied in a variety of sit ....Innovative Bayesian statistics for enhanced decision making for pharmaceutical drug development. This project addresses Australia's national research priority of Promoting and Maintaining Good Health, and will lead to improvements in health outcomes by patients accessing new drugs sooner, enhancing research, and reducing the cost of health care. Decision making in early stages of drug development will be improved by using novel statistical methods, which could also be applied in a variety of situations involving decision making procedures. This will be achieved through cross-disciplinary and university-industry collaboration, utilising Australian and international expertise. National demands for quality science and trained researchers underpinning health decisions will be contributed to.Read moreRead less
Patterns of connectivity and hot-spots of recruitment: a basis for prioritising high value coastal rivers. Provision of water for agricultural, industrial and residential use is becoming increasingly difficult in Australia. By determining the need for important migratory fish species to have access to marine conditions, this project aims to assist managers to identify river systems where changing flow patterns will be particularly detrimental. The project will provide information about the ne ....Patterns of connectivity and hot-spots of recruitment: a basis for prioritising high value coastal rivers. Provision of water for agricultural, industrial and residential use is becoming increasingly difficult in Australia. By determining the need for important migratory fish species to have access to marine conditions, this project aims to assist managers to identify river systems where changing flow patterns will be particularly detrimental. The project will provide information about the need for artificial opening of estuary mouths, fish ladders and other practical means to ensure the continued survival of these species. Read moreRead less
Next generation metagenomics. Applying the latest scientific advances supports society directly through promoting a knowledge based economy, as well as indirectly through securing agricultural productivity, improved biomedical applications and a greater understanding of our changing environment. Establishing these methods places Australia at the forefront of genomics technology with direct applications for Australian biomedical and biotechnology industries. Applying next generation sequencing fo ....Next generation metagenomics. Applying the latest scientific advances supports society directly through promoting a knowledge based economy, as well as indirectly through securing agricultural productivity, improved biomedical applications and a greater understanding of our changing environment. Establishing these methods places Australia at the forefront of genomics technology with direct applications for Australian biomedical and biotechnology industries. Applying next generation sequencing for metagenomics will provide a detailed understanding of microbial population structures and lead to advances in biomedicine, agriculture and environmental science. Read moreRead less
The importance of price and perceived quality to the demand for fresh fruits and vegetables. It is estimated that the direct and indirect cost of diet-related diseases to Australia is between $2-3 billion per annum. One of the most important things that can be done to prevent diet-related disease is to encourage the population to eat more fruits and vegetables. The aim of this project is to examine the effect of price and perceived quality on the type and quantity of fruits and vegetables cons ....The importance of price and perceived quality to the demand for fresh fruits and vegetables. It is estimated that the direct and indirect cost of diet-related diseases to Australia is between $2-3 billion per annum. One of the most important things that can be done to prevent diet-related disease is to encourage the population to eat more fruits and vegetables. The aim of this project is to examine the effect of price and perceived quality on the type and quantity of fruits and vegetables consumed, especially among low-income households. The project will employ modelling techniques that are novel to this product group and that will provide valuable insights to the constraints and opportunities for increasing fruits and vegetables intake, as well as benchmarks for future research.Read moreRead less
Towards selective breeding of pearl oysters - quantitative and population genetics of the silver-lipped pearl oyster Pinctada maxima. Successful selective breeding programs rely on two critical factors; i) an understanding of the genetic processes underpinning phenotypic expression of commercially important traits and ii) a reliable method to retain pedigrees so that the rate of inbreeding can be controlled. This project will utilise modern quantitative and molecular genetic approaches to genera ....Towards selective breeding of pearl oysters - quantitative and population genetics of the silver-lipped pearl oyster Pinctada maxima. Successful selective breeding programs rely on two critical factors; i) an understanding of the genetic processes underpinning phenotypic expression of commercially important traits and ii) a reliable method to retain pedigrees so that the rate of inbreeding can be controlled. This project will utilise modern quantitative and molecular genetic approaches to generate for the first time fundamental information on the role genetics has on growth and pearl quality traits in the silver-lipped pearl oyster Pinctada maxima. Outcomes from this project when integrated into a selective breeding program for this species will dramatically transform the international competitiveness of this valuable industry.Read moreRead less
Linking genes with the phenotype - creation of a genetic linkage map for the silver-lipped pearl oyster Pinctada maxima. R&D undertaken in this project will increase our fundamental understanding of the role genetics plays in production of a premium quality cultured South Sea pearl. When utilised in future selective breeding programs aimed at improving pearl quality traits the information generated will allow Australian pearling companies to be more productive and to maintain a competitive advan ....Linking genes with the phenotype - creation of a genetic linkage map for the silver-lipped pearl oyster Pinctada maxima. R&D undertaken in this project will increase our fundamental understanding of the role genetics plays in production of a premium quality cultured South Sea pearl. When utilised in future selective breeding programs aimed at improving pearl quality traits the information generated will allow Australian pearling companies to be more productive and to maintain a competitive advantage over their rivals. Many rural communities are dependent on pearling companies for their economic prosperity and community identity. Consequently, positive growth of the pearl industry as a result of the proposed R&D will greatly benefit the economic and social wealth of these rural populations.Read moreRead less