Prof Speed is a statistician specializing in bioinformatics and computational biology, applying my skills in support of basic research in molecular and cell biology and genetics.
I am a statistician specializing in bioinformatics and computational biology, applying my skills in support of basic research in molecular and cell biology and genetics.
Novel Statistical Methods For The Analysis Of Meausred Genetic And Environmental Risk Factors In Twin Studies
Funder
National Health and Medical Research Council
Funding Amount
$478,314.00
Summary
Studies on twins are an important way to determine whether the risk of disease is likely to be influenced by genetic factors but have traditionally focussed on unmeasured factors. New epidemiological studies measure thousands of genetic variants on many participants. This project will extend methods for analysing data within and between twin pairs to determine whether risk factors are likely to be causal and therefore should be the subject of further designed studies based on intervention.
How Do Media Campaigns And Tobacco-relevant News Coverage Influence Adolescent And Adult Smoking?
Funder
National Health and Medical Research Council
Funding Amount
$411,177.00
Summary
The study will merge measures of exposure to televised anti-smoking advertising, press coverage about tobacco issues and other tobacco control policies with (a) an annually interviewed cohort of 2,000 adult smokers from 2002-2008 and (b) triennial surveys of smoking among adolescents 1993-2008 (n-150,000). Analysis will determine the role of anti-smoking advertising and tobacco-related press coverage in moving smokers towards quitting and changing adolescent smoking.
Development And Evaluation Of Statistical Methods And Software For Analysis Of Complex Genetic Disease Data
Funder
National Health and Medical Research Council
Funding Amount
$1,250,371.00
Summary
What are the major factors underpinning complex genetic diseases like diabetes, bipolar disorder or cancer? To answer this question new tools are needed, including software for mining the human genome with interactions between the genome and environment being incorporated. This is our focus. It will form the basis of a superior understanding of the overall process leading to disease and hence better predictions with important ramifications for new treatments and health care planning.
Projecting Prevalence By Phase Of Care For Colorectal, Lung, Breast And Prostate Cancer In New South Wales
Funder
National Health and Medical Research Council
Funding Amount
$330,848.00
Summary
Cancer will become the top health issue in Australia due to the growth and ageing of the population. Accurate estimates of the numbers of people in the community at the different stages of their cancer journey (phases of care) now and in the future are required to plan for and provide adequate cancer care services. We will develop statistical models to estimate and predict cancer prevalence by phase of care for four major cancers in New South Wales.