Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant ....Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant contributions to the new and evolving priority research area of Bioinformation Science (including bioinformatics). Outcomes will include novel techniques for analysis and mining of post-genome data, with applications to developments in Bio-medicine and Bio-agricultureRead moreRead less
Mathematical Methods for Next Generation Sequencing. The emergence of a new generation of high throughput genomic sequencing technologies is providing unprecedented opportunities for biological research. Hidden within the huge amounts of data generated by this technology is information about the expression and regulation of genes, and the complex functional purpose of non-coding, so called 'junk', DNA. Development of mathematical and statistical tools is essential to interpreting these data. The ....Mathematical Methods for Next Generation Sequencing. The emergence of a new generation of high throughput genomic sequencing technologies is providing unprecedented opportunities for biological research. Hidden within the huge amounts of data generated by this technology is information about the expression and regulation of genes, and the complex functional purpose of non-coding, so called 'junk', DNA. Development of mathematical and statistical tools is essential to interpreting these data. The proposed research will enhance Australia's reputation for developing novel quantitative techniques at the cutting edge of modern biology. The proposed project has a broad range of potential applications in biotechnology, particularly in the medical and agricultural industries.Read moreRead less
Sequence to Sequence: Rigorous Statistical and Mathematical Analysis of Biological Sequence Data. Comparative genomics is fundamental for developing an understanding of genes and their function. For example, using statistical and computational techniques, it was recently demonstrated that 60% of genes are conserved between fly and human. When the human gene that confers susceptibility to Parkinson's disease was transferred into the fly it caused symptoms similar to those seen in humans. The futu ....Sequence to Sequence: Rigorous Statistical and Mathematical Analysis of Biological Sequence Data. Comparative genomics is fundamental for developing an understanding of genes and their function. For example, using statistical and computational techniques, it was recently demonstrated that 60% of genes are conserved between fly and human. When the human gene that confers susceptibility to Parkinson's disease was transferred into the fly it caused symptoms similar to those seen in humans. The future development of 'personalized medicine' will rely upon understanding the function of human genes, as will progress in the agricultural sector. Rigorous statistical analysis and development of appropriate bioinformatic methods are crucial to biological sequence analysis in comparative genomics.Read moreRead less
Increasing internet energy and cost efficiency by improving higher-layer protocols. Australians rely heavily on our telecommunications infrastructure due to our geographic dispersion. We are also very susceptible to climate change, given our reliance on agriculture. Information technology is consuming a rapidly increasing fraction of our power and our budget. This research will help to reverse both those trends, by finding novel and practical ways to use our infrastructure more efficiently, and ....Increasing internet energy and cost efficiency by improving higher-layer protocols. Australians rely heavily on our telecommunications infrastructure due to our geographic dispersion. We are also very susceptible to climate change, given our reliance on agriculture. Information technology is consuming a rapidly increasing fraction of our power and our budget. This research will help to reverse both those trends, by finding novel and practical ways to use our infrastructure more efficiently, and to minimise its energy use. This will enable the Australian telecommunications industry to provide better service (including to Australian industries and rural communities) at lower economic and environmental cost. This project will put Australia on the international stage as a leading contributor to energy-efficient internet technology.Read moreRead less
ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functi ....ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functional materials, ii) high-tech IT/communications/sensing materials, iii) materials solutions for manufacturing, iv) materials for a sustainable Australia, and v) emerging materials technologies. Key programs will promote interdisciplinary workshops and early career researcher interactions.Read moreRead less
Special Research Initiatives - Grant ID: SR0354605
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high per ....The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high performance computing through open sourced middleware. The result will be an unparalleled predictive capacity for complex Earth systems. The outcome will be confidence in the knowledge that underpins our decisions as stakeholders to keep Australia sustainable.Read moreRead less
Uncoupling past salinity and temperature signals in the Indo-Pacific Warm Pool: implications for climate change in the Australian region. The tropical oceans and in particular the Indo-Pacific Warm Pool, immediately to Australia's north, play a key role in modulating global and Australian climate through El-Niño and related phenomena. Using a new microanalysis approach to analyse individual foraminifera from deep-sea cores, we will reconstruct past salinity and temperature variability within the ....Uncoupling past salinity and temperature signals in the Indo-Pacific Warm Pool: implications for climate change in the Australian region. The tropical oceans and in particular the Indo-Pacific Warm Pool, immediately to Australia's north, play a key role in modulating global and Australian climate through El-Niño and related phenomena. Using a new microanalysis approach to analyse individual foraminifera from deep-sea cores, we will reconstruct past salinity and temperature variability within the Warm Pool, and determine changing rainfall patterns and, ENSO and monsoon behaviour under climate conditions that lie outside modern records. This information is vital for understanding past climate and predicting the future intensity and frequency of El-Niño related drought and wet cycles in Australia.Read moreRead less
ARC Nanotechnology Research Network. The field of nano scale science, engineering and technology (in short nanotechnology) is just emerging and it is predicted to make a major impact in all technologies and areas of society. Australian Nanotechnology Network intends to harness the combined Australian capability to enable Australia to take a leading role in this rapidly growing field.
Special Research Initiatives - Grant ID: SR0354623
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Network for Australian security technologies integration. The frontline of community safety is security technologies which include sensors to track movements and conversations of suspects; signal processing techniques for extracting information; intelligent search/audit techniques to track financial transactions; analysis techniques for predicting the spread of epidemic; and above all human factors in security operations. The aim of this initiative is to establish a network for "safeguarding Aus ....Network for Australian security technologies integration. The frontline of community safety is security technologies which include sensors to track movements and conversations of suspects; signal processing techniques for extracting information; intelligent search/audit techniques to track financial transactions; analysis techniques for predicting the spread of epidemic; and above all human factors in security operations. The aim of this initiative is to establish a network for "safeguarding Australia". This network, built on the concept of "network of networks", draws on the expertise of researchers and practitioners from diverse fields to provide an integrated approach towards development and use of security technologies for the safety of the community.Read moreRead less
Preparation of silica-based thin film materials with large optical nonlinearity. There is currently a lack of advanced thin film materials suitable for fabricating integrated electro-optic devices to use in optical telecommunication. Such materials will be produced, and their application will be developed through this project. The physical mechanism of the marvelous optical nonlinearities of the materials will also be investigated. Thus the achievement of this project will bring great advancemen ....Preparation of silica-based thin film materials with large optical nonlinearity. There is currently a lack of advanced thin film materials suitable for fabricating integrated electro-optic devices to use in optical telecommunication. Such materials will be produced, and their application will be developed through this project. The physical mechanism of the marvelous optical nonlinearities of the materials will also be investigated. Thus the achievement of this project will bring great advancement in both scientific knowledge and technologies for Australia, and provide huge opportunities to boost Australian telecommunication industries, which are developing quickly in recent years.Read moreRead less