Probing the function of protein molecular motors on nano-fabricated structures. The function of protein linear molecular motors, which are natural dynamic bio-nano-devices with a ubiquitous importance in multicellular organisms, will be 'probed' with purposefully designed nano-structures fabricated via photo- or Scanning Probe Microscopy Lithography, that is, flat polymeric surfaces with combinatorial combinations of physico-chemistries; and micro/nano-channels and nano-wells with critical dimen ....Probing the function of protein molecular motors on nano-fabricated structures. The function of protein linear molecular motors, which are natural dynamic bio-nano-devices with a ubiquitous importance in multicellular organisms, will be 'probed' with purposefully designed nano-structures fabricated via photo- or Scanning Probe Microscopy Lithography, that is, flat polymeric surfaces with combinatorial combinations of physico-chemistries; and micro/nano-channels and nano-wells with critical dimensions similar to the scale of the probed biomolecules. The project turns 'up-side down' the challenge of invasive nano-probing of biomolecules using it in an engineered manner. The fundamental understanding of linear molecular motors will impact on biomedical science and on the assessment of hybrid natural-artificial dynamic nano-devices.Read moreRead less
Nano-scale modification of gold surfaces for sensing mercury from gaseous effluents of alumina refineries. The Australian alumina industry contributes more than $5.4 billion export income annually. It is also a major driver of the rural economy with all but one of Australia's seven alumina refineries located in rural areas. In response to the industry's attempts to reduce the environmental impact of its processes, this project will conduct basic strategic research into the interaction between m ....Nano-scale modification of gold surfaces for sensing mercury from gaseous effluents of alumina refineries. The Australian alumina industry contributes more than $5.4 billion export income annually. It is also a major driver of the rural economy with all but one of Australia's seven alumina refineries located in rural areas. In response to the industry's attempts to reduce the environmental impact of its processes, this project will conduct basic strategic research into the interaction between mercury vapour and gold surfaces at the nano-level. Our principal aim is to develop mercury sensor technology suited to alumina refineries. This innovative technology will be a significant breakthrough in the control of mercury emissions and have many other applications.
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Industrial Transformation Research Hubs - Grant ID: IH210100040
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this ....ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this Hub include advanced manufacturing capacity for connected sensors, strategic partnerships and commercialisation skills to translate sensors research to create economic benefits such as jobs and locally-made products for domestic and export markets, as well as improving the health of Australians.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989068
Funder
Australian Research Council
Funding Amount
$637,120.00
Summary
Equipment for Metastable Induced Electron Spectroscopy: surface analysis with excellent surface sensitivity. One of the major research strengths of Australia is surface science as it is important for both fundamental and industry related research. In many cases it is crucial to investigate the outermost layer of a material or mineral. Metastable Induced Electron Spectroscopy is an ideal technique as it is sensitive exclusively to the outermost layer of a broad range of samples. The information g ....Equipment for Metastable Induced Electron Spectroscopy: surface analysis with excellent surface sensitivity. One of the major research strengths of Australia is surface science as it is important for both fundamental and industry related research. In many cases it is crucial to investigate the outermost layer of a material or mineral. Metastable Induced Electron Spectroscopy is an ideal technique as it is sensitive exclusively to the outermost layer of a broad range of samples. The information gained is not accessible by any other method. The proposed equipment will be the first of this type in Australia and will complement existing surface science facilities. The project will enhance Australia's position in surface science internationally and a large number of projects will benefit from access to the equipment.Read moreRead less
Characterisation and fabrication of nanophotonic devices based on multi-layer stacks. The aim of this proposal is to continue the existing collaborative project on fabrication and characterisation of nanophotonic devices based on the multi-layer stack method. The project will integrate the state-of-the-art techniques in the respective collaborating universities to fabricate a nano-probe which can produce an evanescent field approximately four orders of magnitude stronger than that under the conv ....Characterisation and fabrication of nanophotonic devices based on multi-layer stacks. The aim of this proposal is to continue the existing collaborative project on fabrication and characterisation of nanophotonic devices based on the multi-layer stack method. The project will integrate the state-of-the-art techniques in the respective collaborating universities to fabricate a nano-probe which can produce an evanescent field approximately four orders of magnitude stronger than that under the conventional condition. This novel probe provides a key to the successful fabrication of innovative nanophotonic devices including photonic transistors, photonic circuits, high-density data storage disks and drives, nano-motors and biochips, which underpin biotechnology, information technology and optical computing technology.Read moreRead less
A novel spectrum encoding technology using nanoparticles for high-density, high-speed information coding and retrieval. The key-sector in high tech markets has been the photonics industry over the last decade, and it will continue to revolutionise our ways of information storage, processing and transfer for the next 10 to 20 years. The current project of novel spectrum-encoding technology will prove to be the key technological innovation in photonics (one of the National Research Priorities), w ....A novel spectrum encoding technology using nanoparticles for high-density, high-speed information coding and retrieval. The key-sector in high tech markets has been the photonics industry over the last decade, and it will continue to revolutionise our ways of information storage, processing and transfer for the next 10 to 20 years. The current project of novel spectrum-encoding technology will prove to be the key technological innovation in photonics (one of the National Research Priorities), which will not only meet the growing demands of the consumer market, but also continue to drive the industry and create new markets. This is in line with the Priority Goals set by the Minister for Education, Science and Training, as it will put Australia into the unique position in the information age.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100172
Funder
Australian Research Council
Funding Amount
$270,000.00
Summary
Inductively-coupled plasma etching facility. Inductively-coupled plasma etching facility: The aim of this project is to bring together an inductively-coupled plasma etcher with a high resolution tool for optical lithography to create a facility capable of producing nano-structures in silicon surfaces. Such structures are the basis of high performance photonic, nano-electronic, and MicroElectroMechanical (MEM) devices. The lithography tool is a step-and-repeat system capable of exceptionally high ....Inductively-coupled plasma etching facility. Inductively-coupled plasma etching facility: The aim of this project is to bring together an inductively-coupled plasma etcher with a high resolution tool for optical lithography to create a facility capable of producing nano-structures in silicon surfaces. Such structures are the basis of high performance photonic, nano-electronic, and MicroElectroMechanical (MEM) devices. The lithography tool is a step-and-repeat system capable of exceptionally high rates of throughput so this etcher will be a crucial enabling tool for efficient fabrication of nano-devices for research into quantum computing, high bandwidth, quantum-secure optical communications, renewable energy, and for applications in medicine. The etcher will be available for national access.Read moreRead less
Enhanced drug delivery using nanoparticulate dendrimer vectors. Many drug candidates fail during development because of low and variable absorption after oral administration. This project seeks to investigate the utility of specialised nanometer-sized macromolecules (dendrimers), to facilitate the improved delivery of drug molecules where low aqueous solubility is the principle limitation to drug absorption and will also be explored as vectors to specifically target drugs to intestinal lymphoid ....Enhanced drug delivery using nanoparticulate dendrimer vectors. Many drug candidates fail during development because of low and variable absorption after oral administration. This project seeks to investigate the utility of specialised nanometer-sized macromolecules (dendrimers), to facilitate the improved delivery of drug molecules where low aqueous solubility is the principle limitation to drug absorption and will also be explored as vectors to specifically target drugs to intestinal lymphoid (immune) tissue. This project will link the drug delivery expertise of Monash University with the experience in dendrimer design of the Australian biotechnology company Starpharma to provide concrete delivery solutions for the rapidly expanding biotechnology industry in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100098
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced facility for next generation sustainable energy, biomedical & nano-imaging optical fibre technologies. Remote optical fibre technologies are the way forward for effective and safe monitoring of many industries, and will play a big part in the sustainability of Australia's core oil, gas and alternative energy sectors. They are equally important to health industry applications, particularly in medical and imaging technologies. This facility brings together world-class Australian expertise ....Advanced facility for next generation sustainable energy, biomedical & nano-imaging optical fibre technologies. Remote optical fibre technologies are the way forward for effective and safe monitoring of many industries, and will play a big part in the sustainability of Australia's core oil, gas and alternative energy sectors. They are equally important to health industry applications, particularly in medical and imaging technologies. This facility brings together world-class Australian expertise—from across nine universities—in advanced structured optical fibres, complex fibre diagnostic systems, nanoscale imaging, and environment monitoring, to design and implement the next generation of technologies that will reduce the impact of climate change through reduced energy consumption and vastly improved health diagnostics.Read moreRead less
Characterisation and Stability of Thin Electrowetting Films. Electrowetting is of importance to numerous industrial, biomedical and daily life settings such as microfluidic biopharmaceutical applications, coating technology, electronic displays, optical focusing devices, miniaturised chemical analysis systems for homeland security, etc. The work, aimed at generating an understanding of the complex hydrodynamic and physicochemical processes involved, is fundamental research having generic benefit ....Characterisation and Stability of Thin Electrowetting Films. Electrowetting is of importance to numerous industrial, biomedical and daily life settings such as microfluidic biopharmaceutical applications, coating technology, electronic displays, optical focusing devices, miniaturised chemical analysis systems for homeland security, etc. The work, aimed at generating an understanding of the complex hydrodynamic and physicochemical processes involved, is fundamental research having generic benefits to researchers in interfacial science, electrokinetics and microfluidics. The results will also be beneficial to industrial workers in providing engineering protocols for the development of these devices by identifying optimal conditions for fluid manipulation without prone-to-wear mechanical components. Read moreRead less