A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of import ....A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of important organic reactions and enhancing collaboration nationally and internationally between computational and synthetic chemists. This should provide significant benefits in the form of improved chemical reactions for chemists to prepare new pharmaceuticals, agrochemicals and materials.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH200100010
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Transformation of Reclaimed Waste Resources to Engineered Materials and Solutions for a Circular Economy. This project aims to create new knowledge to reduce waste going to landfills and transform reclaimed waste into new materials for use in construction and other manufacturing sectors. It integrates multisector input and multidisciplinary academic research to address ten challenging waste streams. Expected outcomes are smart materials, socio-technical change, accelerated t ....ARC Research Hub for Transformation of Reclaimed Waste Resources to Engineered Materials and Solutions for a Circular Economy. This project aims to create new knowledge to reduce waste going to landfills and transform reclaimed waste into new materials for use in construction and other manufacturing sectors. It integrates multisector input and multidisciplinary academic research to address ten challenging waste streams. Expected outcomes are smart materials, socio-technical change, accelerated testing methods, predictive modeling, circular life cycle costing and a trusted evidence base. Outcomes will lead to commercial benefits as well as jobs and a significant contribution to addressing the pressing environmental impacts of waste production, management, and re-use.Read moreRead less
Seaweed forests of the future: responses to ocean acidification and warming. The aim is to discover if rising levels of oceanic carbon dioxide will offset negative effects of ocean warming on seaweeds, using targeted physiological experiments together with novel molecular diagnostics. Seaweeds create habitats and food for shellfish and fish, and play a crucial role in long term ‘blue carbon’ storage. They are predicted to benefit from future carbon dioxide enrichment, but to test this forecast r ....Seaweed forests of the future: responses to ocean acidification and warming. The aim is to discover if rising levels of oceanic carbon dioxide will offset negative effects of ocean warming on seaweeds, using targeted physiological experiments together with novel molecular diagnostics. Seaweeds create habitats and food for shellfish and fish, and play a crucial role in long term ‘blue carbon’ storage. They are predicted to benefit from future carbon dioxide enrichment, but to test this forecast requires a detailed understanding of the mechanisms used by seaweeds to acquire dissolved inorganic carbon. The expected outcome is robust predictions of how the primary productivity of coastal waters will respond to future high carbon dioxide conditions, enabling human adaptation to environmental change.
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Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild ba ....Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild barley and identify appropriate candidate genes and their position on chromosomes for further incorporating these traits into commercial barley cultivars. This will reduce the environmental footprint of modern agricultural practices on terrestrial and aquatic ecosystems without compromising food security.Read moreRead less
Three-dimensional Bayesian Modelling of Geological and Geophysical data. The project aims to develop technologies enabling rapid informed decision-making related to the management of natural resources, including critical metals, copper and water. This new technology will support a greener future, securing our energy future, our access to clean water and reduce the mining footprint. Expected outcomes include an enhanced capability in interoperable, integrated three-dimensional geological and geop ....Three-dimensional Bayesian Modelling of Geological and Geophysical data. The project aims to develop technologies enabling rapid informed decision-making related to the management of natural resources, including critical metals, copper and water. This new technology will support a greener future, securing our energy future, our access to clean water and reduce the mining footprint. Expected outcomes include an enhanced capability in interoperable, integrated three-dimensional geological and geophysical modelling in order to predictively characterise sub-surface geology. The outcome will be an open-source forecasting dashboard enabling decision making while considering underlying risk related to resource extractions and management with significant benefits to the Australian society (lower emissions, clean water).Read moreRead less
Function and evolution of insect odorant receptors. This project aims to shed light on how insect odorant receptors function by using comparative genomic studies between the genetic model insect Drosophila melanogaster and a pest species, the Australian sheep blowfly. This project expects to generate knowledge of how specific chemicals activate specific receptors in order to excite sensory neurons and drive behaviour, which is not well understood. Expected outcomes include increased understandin ....Function and evolution of insect odorant receptors. This project aims to shed light on how insect odorant receptors function by using comparative genomic studies between the genetic model insect Drosophila melanogaster and a pest species, the Australian sheep blowfly. This project expects to generate knowledge of how specific chemicals activate specific receptors in order to excite sensory neurons and drive behaviour, which is not well understood. Expected outcomes include increased understanding of olfaction in insects, increased national and international collaboration, and outstanding graduate student training. This research will be of significant future benefit in deriving methods to modify the behaviour of insects of agricultural or medical importance, for example the sheep blowfly. Read moreRead less
Understanding climate and harvest induced changes in fish life histories. This project aims to quantify the cumulative impacts of harvest and climate change across marine fishes and ecosystems. The project expects to generate new knowledge in this area by coupling the rich biological information archived in fish ear bones, with targeted multi-generation experiments and predictive modelling. Expected outcomes include fundamental insights into how human-induced environmental change affects fish gr ....Understanding climate and harvest induced changes in fish life histories. This project aims to quantify the cumulative impacts of harvest and climate change across marine fishes and ecosystems. The project expects to generate new knowledge in this area by coupling the rich biological information archived in fish ear bones, with targeted multi-generation experiments and predictive modelling. Expected outcomes include fundamental insights into how human-induced environmental change affects fish growth and maturation, and a subsequent critical evaluation of the sensitivity of fisheries models to trends in these life-history traits. This should provide significant benefits to fisheries and ecosystem management, ensuring they remain productive and resilient in a time of rapid environmental change.Read moreRead less
Detecting and deciphering extinction dynamics under environmental change. This project aims to improve knowledge of extinction processes and impacts. It will use high-performance computing and museum collections to disentangle the ecological mechanisms that were integral in the initial decline and later extinction of Australia's unique mammals. Its significance is that it will establish the historical ranges and past population trajectories of Australian threatened mammals, pinpointing the combi ....Detecting and deciphering extinction dynamics under environmental change. This project aims to improve knowledge of extinction processes and impacts. It will use high-performance computing and museum collections to disentangle the ecological mechanisms that were integral in the initial decline and later extinction of Australia's unique mammals. Its significance is that it will establish the historical ranges and past population trajectories of Australian threatened mammals, pinpointing the combinations of ecological characteristics and threats that most affect risk of extinction from environmental change. Expected outcomes and benefits are new data and verified models to enrich conservation research and inform evidence-based solutions to better protect and recover some of Australia’s most threatened species.Read moreRead less
Contact Networks, Immunity, and Evolution in Competing Cancer Epidemics. The project aims to evaluate evolutionary interactions between two transmissible cancer epidemics affecting Tasmanian devils and quantify their feedback on infection risk and epidemic behaviour. Using contact tracing and a phylogenetic framework we aim to quantify how tumour lineages evolve with each generation of infection and their effects on susceptibility to infection and disease progression. We expect to reveal the hos ....Contact Networks, Immunity, and Evolution in Competing Cancer Epidemics. The project aims to evaluate evolutionary interactions between two transmissible cancer epidemics affecting Tasmanian devils and quantify their feedback on infection risk and epidemic behaviour. Using contact tracing and a phylogenetic framework we aim to quantify how tumour lineages evolve with each generation of infection and their effects on susceptibility to infection and disease progression. We expect to reveal the host immuno-genetic basis underpinning cancer suppression and the adaptive capacity of populations in response to infectious diseases. This should significantly improve our ability to understand and manage this and other epidemic outbreaks in wildlife, as well as advancing our knowledge in cancer ecology and evolution.Read moreRead less