Performance Characteristics of an Innovative Structural System - Compound Curved Sandwich Shell Structure. An innovative structural system utilising sandwich panel technology and shell action has recently emerged. These aesthetically pleasing curved structures are durable and spacious with fast construction time. They have residential and commercial applications and have attracted considerable local and overseas interest. There are no definitive procedures for their analysis and design and thei ....Performance Characteristics of an Innovative Structural System - Compound Curved Sandwich Shell Structure. An innovative structural system utilising sandwich panel technology and shell action has recently emerged. These aesthetically pleasing curved structures are durable and spacious with fast construction time. They have residential and commercial applications and have attracted considerable local and overseas interest. There are no definitive procedures for their analysis and design and their behaviour is complex involving many variables such as sandwich layer interaction, shape, openings, structural action, etc. This project will generate fundamental knowledge on their behaviour over a range of properties and operating conditions and develop guidelines to ensure safe and economical design, bringing economic benefits to Australia.Read moreRead less
ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ....ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ultimately harness the Grid, enabling linkage into other national and international Grid systems. Encompassing physics, computer science, applied mathematics, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all five National Research Priority 3 goals.Read moreRead less
Special Research Initiatives - Grant ID: SR0354691
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
A Grid Enabled Network for the Molecular and Materials Structure Sciences. The Molecular and Materials Structure Network will propel leading-edge Science by building powerful e-Science resources that will compel innovative collaborations of profound National benefit. Remote access will be developed for structure determination instruments, including the Research Reactor and Australian Synchrotron. A structure database with cross disciplinary content and powerful visualisation and analysis capabil ....A Grid Enabled Network for the Molecular and Materials Structure Sciences. The Molecular and Materials Structure Network will propel leading-edge Science by building powerful e-Science resources that will compel innovative collaborations of profound National benefit. Remote access will be developed for structure determination instruments, including the Research Reactor and Australian Synchrotron. A structure database with cross disciplinary content and powerful visualisation and analysis capabilities will exemplify "smart information use". Encompassing physics, computer science, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all four National Research Priority 3 goals, and will be linked to other national and international Grids to become part of the emerging global Grid.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882787
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
An Integrated Raman Microscope and in Situ STM-TEM Analysis System. The imaging and analytical capabilities of SEM and chemical and structural characterisation afforded by Raman spectroscopy will be unique, allowing both rapid morphological observation and elemental analysis at the macro and nanoscale. The in-situ TEM holder will further assist through in-situ characterization of advanced materials at the nano-scale level. In combination, these instruments will underpin groundbreaking research i ....An Integrated Raman Microscope and in Situ STM-TEM Analysis System. The imaging and analytical capabilities of SEM and chemical and structural characterisation afforded by Raman spectroscopy will be unique, allowing both rapid morphological observation and elemental analysis at the macro and nanoscale. The in-situ TEM holder will further assist through in-situ characterization of advanced materials at the nano-scale level. In combination, these instruments will underpin groundbreaking research in diverse research fields developing new advanced nanomaterials and bio-nanomaterials with significant impact on many industries with great economical and environmental benefits. Read moreRead less
Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these w ....Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these ways, in order to provide the information necessary to refine procedures and design new molecules suitable for advanced applications. Expected outcomes are new methods and architectures that can ultimately yield devices that act at the molecular level.Read moreRead less
Novel approaches for structural and functional analysis of the protein complex COG, a tether that controls intra-Golgi trafficking. Production and engineering of proteins are key methodologies of the life sciences in general and biotechnology in particular. Our ability to produce and analyse protein-based components of the cell determines the expense and speed of discovery, as well as the creation of new vaccines, drugs, and diagnostic methods. The current project aims to develop new approaches ....Novel approaches for structural and functional analysis of the protein complex COG, a tether that controls intra-Golgi trafficking. Production and engineering of proteins are key methodologies of the life sciences in general and biotechnology in particular. Our ability to produce and analyse protein-based components of the cell determines the expense and speed of discovery, as well as the creation of new vaccines, drugs, and diagnostic methods. The current project aims to develop new approaches for protein production and to apply them to the analysis of the basic mechanisms of cell self-maintenance.Read moreRead less
Novel Synthesis and Bio-applications of Functional Macroporous Ordered Siliceous Foams. This project will lead to advances in materials science and nanotechnology, providing high efficiency separation and purification for viruses or plasmid deoxyribonucleic acid (DNA), which are important in modern gene engineering for the treatment of genetic and acquired diseases. Application benefits also include developing a new protocol in the detection of trace amount proteins, which will afford a signific ....Novel Synthesis and Bio-applications of Functional Macroporous Ordered Siliceous Foams. This project will lead to advances in materials science and nanotechnology, providing high efficiency separation and purification for viruses or plasmid deoxyribonucleic acid (DNA), which are important in modern gene engineering for the treatment of genetic and acquired diseases. Application benefits also include developing a new protocol in the detection of trace amount proteins, which will afford a significant improvement in diverse fields such as health care. Through this project, novel macroporous materials will be fabricated using an economically and environmentally sustainable approach. These new materials will have unique structures and properties compared to conventional macroporous materials, advancing Australia's intellectual position in this discipline.Read moreRead less
The molecular mechanism of retromer and sorting nexin function in endosomal membrane trafficking. The proposed research represents breakthrough science that will lead to a fundamental understanding at the molecular level of the structure and assembly of the retromer complex and how it regulates sorting of receptors in the endosomal system. It will provide excellent research training for top graduate students and post-doctoral scientists in multidisciplinary methods that constitute state-of the- ....The molecular mechanism of retromer and sorting nexin function in endosomal membrane trafficking. The proposed research represents breakthrough science that will lead to a fundamental understanding at the molecular level of the structure and assembly of the retromer complex and how it regulates sorting of receptors in the endosomal system. It will provide excellent research training for top graduate students and post-doctoral scientists in multidisciplinary methods that constitute state-of the-art structural and molecular cell biology research. By addressing an area of great interest internationally the project will have the capacity to increase Australia's knowledge base and strengthen it's reputation for research excellence.Read moreRead less
Controllable growth of semiconductor quantum dots for future nanoelectronic and optoelectronic devices. This project addresses specific National Research Priorities in the areas of breakthrough science, frontier technology and advanced materials. Outcomes will significantly advance the understanding of the self-assembly of semiconductor nanostructures. This project will provide informative guidelines for designing, developing and manufacturing semiconductor nanostructures for future nanoelectron ....Controllable growth of semiconductor quantum dots for future nanoelectronic and optoelectronic devices. This project addresses specific National Research Priorities in the areas of breakthrough science, frontier technology and advanced materials. Outcomes will significantly advance the understanding of the self-assembly of semiconductor nanostructures. This project will provide informative guidelines for designing, developing and manufacturing semiconductor nanostructures for future nanoelectronic and optoelectronic devices, which is strategically important to Australia's emerging electronic industry. This project will also enhance the international reputation and impact of Australian research in the internationally focused field of nanoscience and nanotechnology.Read moreRead less
Endosomal Protein Transport: From Molecular Structures to Biological Function. Intracellular transport of biomolecules through the endosomal organelle is critical for normal cellular processes such as signalling, homoeostasis and development. Defects in this fundamental process and subversion of it by bacterial and viral pathogens also lead to many different human diseases. This project will build on Australia's strong programme of structural and cellular biology research to develop key insights ....Endosomal Protein Transport: From Molecular Structures to Biological Function. Intracellular transport of biomolecules through the endosomal organelle is critical for normal cellular processes such as signalling, homoeostasis and development. Defects in this fundamental process and subversion of it by bacterial and viral pathogens also lead to many different human diseases. This project will build on Australia's strong programme of structural and cellular biology research to develop key insights into endosomal trafficking at the molecular level. Outcomes from this work will place Australia at the forefront of international efforts to understand this essential biological process and will have important implications for future design of pharmaceuticals.Read moreRead less