Programming of appetite and bodyweight by the interaction of maternal diet and angiotensin during peri-natal life. The project describes a phenotype for appetite and body weight that can be altered by maternal dietary omega-3 PUFA (environmental factors), at a critical period during peri-natal life (developmental phase) and that the effect on body weight is opposite when endogenous angiotensin is increased (hormonal factor). The project aims to discover how these different factors interact to p ....Programming of appetite and bodyweight by the interaction of maternal diet and angiotensin during peri-natal life. The project describes a phenotype for appetite and body weight that can be altered by maternal dietary omega-3 PUFA (environmental factors), at a critical period during peri-natal life (developmental phase) and that the effect on body weight is opposite when endogenous angiotensin is increased (hormonal factor). The project aims to discover how these different factors interact to produce the phenotype by defining the critical period and systematically identifying genes that are expressed during this period. The effect of manipulating maternal dietary omega-3 PUFA and the role of angiotensin will then be examined. The project will discover how genetic, hormonal and environmental factors interact during the perinatal period of life to program food intake and body weight in adult life. Read moreRead less
Gene Discovery and Functional Analysis of Copper Homeostasis Genes in Drosophila. Copper is a vital nutrient required for the formation and maintenance of bones, blood vessels and the central nervous system, but copper is also potentially toxic when in excess. Homeostatic mechanisms are needed to maintain safe levels of copper in the body and disruptions to these mechanisms are associated with disorders such as Alzheimer's disease, heart disease and osteoporosis. We are investigating the regulat ....Gene Discovery and Functional Analysis of Copper Homeostasis Genes in Drosophila. Copper is a vital nutrient required for the formation and maintenance of bones, blood vessels and the central nervous system, but copper is also potentially toxic when in excess. Homeostatic mechanisms are needed to maintain safe levels of copper in the body and disruptions to these mechanisms are associated with disorders such as Alzheimer's disease, heart disease and osteoporosis. We are investigating the regulation of a key copper pump, the Menkes protein, which helps control copper levels in the body and we are using the genetic advantages of the fruit fly Drosophila to discover new genes that regulate Menkes activity and therefore copper levels. These studies could lead to novel therapies for a range of copper-related disorders.Read moreRead less
Reducing the social, economic and health burden associated with obesity-related chronic diseases among socio-economically disadvantaged populations. This project will develop new methods and approaches for reducing obesity-related chronic diseases (OCDs) among socially disadvantaged populations in Australia, using prevention models. These prevention models will improve the evidence base in this field as well as inform public health policy and practice in Australia (and other industrialised count ....Reducing the social, economic and health burden associated with obesity-related chronic diseases among socio-economically disadvantaged populations. This project will develop new methods and approaches for reducing obesity-related chronic diseases (OCDs) among socially disadvantaged populations in Australia, using prevention models. These prevention models will improve the evidence base in this field as well as inform public health policy and practice in Australia (and other industrialised countries).Read moreRead less
Improving eating behaviours in low-income communities. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Fruit and vegetable consumption is an important part of a healthy diet. Increasing Australians' fruit and vegetable consumption will substantially cut health care costs, ....Improving eating behaviours in low-income communities. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Fruit and vegetable consumption is an important part of a healthy diet. Increasing Australians' fruit and vegetable consumption will substantially cut health care costs, improve quality of life, and boost Australia's fresh produce industry. Findings will directly inform an evidence base upon which to design appropriate policies and programs aimed at promoting fruit and vegetable consumption in socioeconomically disadvantaged groups. Read moreRead less
Understanding environmental drivers of socioeconomic inequalities in food consumption. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Improving Australians' diet will cut health care costs, improve quality of life, and promote physical, mental and social functioning. In o ....Understanding environmental drivers of socioeconomic inequalities in food consumption. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Improving Australians' diet will cut health care costs, improve quality of life, and promote physical, mental and social functioning. In order to improve diet, particularly among those who are disadvantaged, a better understanding of the environmental drivers of inequalities in food consumption is required. Findings will inform the development of policies to increase the availability and accessibility of foodstuffs to supply an adequate and affordable diet for all.Read moreRead less
Trade policy: maximising benefits for nutrition, food security, human health, and the economy. Depending on how it is done, trade can be good or bad for peoples' health and social well-being. This study will provide evidence to support the development of trade policy which combines economic as well as social and health goals. This will help improve global food security and human health, reduce poverty and support good international relations.