Discovery Early Career Researcher Award - Grant ID: DE220100456
Funder
Australian Research Council
Funding Amount
$375,288.00
Summary
The interaction between injury compensation and social security systems. With the ultimate goal of reducing the road traffic crash burden in Australia, on individuals, their families, and on the nation's social support systems, the project will determine the impact of pre-claim social factors on compensation system outcomes including claim duration, benefits and costs, and the impact of compensation system design on claim and social outcomes of road traffic crash survivors. Addressing an unmet n ....The interaction between injury compensation and social security systems. With the ultimate goal of reducing the road traffic crash burden in Australia, on individuals, their families, and on the nation's social support systems, the project will determine the impact of pre-claim social factors on compensation system outcomes including claim duration, benefits and costs, and the impact of compensation system design on claim and social outcomes of road traffic crash survivors. Addressing an unmet need, this project will determine the impact of macro-level compensation system design on social and claim outcomes and allows identification of groups at higher risk for poor post-crash outcomes, in whom earlier identification and intervention can improve these, and potentially save the Australian economy $300m annually.Read moreRead less
Paediatric Validating Injury Burden Estimates Study (VIBES-Junior)
Funder
National Health and Medical Research Council
Funding Amount
$484,562.00
Summary
Injury is a leading cause of death and disability in children and adolescents, and can have lifelong effects for survivors. This study will quantify how well children recover from injury, and how long this takes, to establish better measures of the population impact of injury sustained in childhood and adolescence. The findings will be used to inform future health and social policy concerning primary prevention of injury in childhood and adolescence and the provision of services after injury.
Cancer Risks From Low-dose Ionising Radiation Following Diagnostic Medical Procedures
Funder
National Health and Medical Research Council
Funding Amount
$750,579.00
Summary
Our study investigates cancer risk following exposure to low doses of ionising radiation from medical procedures. Our first major paper linked over 800,000 CT exposures to cancer outcomes in a cohort of almost 11 million young Australians, and found that CT exposure predicted an increased incidence of leukaemia and most solid cancers. In our ongoing work we will incorporate nuclear medicine and other diagnostic x-rays, and estimate radiation dose for individual procedures and to specific organs.
Genetic, Family And Social Determinants Of The Burden And Outcome In Rett Syndrome: A Population-based Investigation
Funder
National Health and Medical Research Council
Funding Amount
$332,550.00
Summary
Rett syndrome is a severe disorder of the nervous system mainly affecting females. At birth children with Rett syndrome often seem normal but in their second year lose skills. With time it becomes clear that they are severely intellectually and physically handicapped. In 1999 the link between Rett syndrome and a mutation in the gene, known as MECP2, was found. In Australia since 1993, we have had a register of basic information on all girls and young women diagnosed with Rett syndrome. Over thre ....Rett syndrome is a severe disorder of the nervous system mainly affecting females. At birth children with Rett syndrome often seem normal but in their second year lose skills. With time it becomes clear that they are severely intellectually and physically handicapped. In 1999 the link between Rett syndrome and a mutation in the gene, known as MECP2, was found. In Australia since 1993, we have had a register of basic information on all girls and young women diagnosed with Rett syndrome. Over three quarters of the register s 248 cases have now been genetically tested. In 2000 and again in 2002, extra information on ability to do everyday tasks, behaviour, hand function, medical conditions, and use of health and education services was collected. In 2002 questions on family well being were also included. From 2004 to 2007, further information will be gathered on function, health and well being of the affected child and their family. This will be by telephone interview, questionnaire, video recording, existing medical records, clinical assessments and tests. This will include in 2004 completion of calendars which will provide information needed to estimate health and medical care costs for these children. Similar information by questionnaire and calendar will also be collected from the parents of children with Down syndrome in 2004. The information will be used to compare the social and financial burden of Rett syndrome with Down syndrome, a commoner cause of intellectual disability. The research will also show if it is possible to predict from early genetic test results how severely a child with Rett syndrome will later be affected. It will also determine whether some ways of management improve the long-term outlook for the girl and her family. Finally this study will investigate why some families cope better with this devastating disorder than others. This research is only possible in Australia because of the ongoing register we have set up here.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101210
Funder
Australian Research Council
Funding Amount
$431,476.00
Summary
Social Inequalities in Oral Health among Australian Working Age Adults. Australian working age adults with social and economic disadvantage have significantly poorer oral health outcomes than those from advantaged backgrounds. This project explores how changes in social position over time, and interactions between different forms of social disadvantage, contribute to social inequalities in oral health. This project expects to improve understanding of social inequalities in oral health, and its s ....Social Inequalities in Oral Health among Australian Working Age Adults. Australian working age adults with social and economic disadvantage have significantly poorer oral health outcomes than those from advantaged backgrounds. This project explores how changes in social position over time, and interactions between different forms of social disadvantage, contribute to social inequalities in oral health. This project expects to improve understanding of social inequalities in oral health, and its solutions, by developing and applying analytical and simulation models. This will help identify ways to reduce the persistent social inequalities in oral health outcomes in working age adults. In doing this, it will inform policies in future that will significantly improve the well-being of Australian working age adults.Read moreRead less
Do Exposures Before Conception Influence The Risk Of Asthma In Offspring?
Funder
National Health and Medical Research Council
Funding Amount
$688,586.00
Summary
Asthma and poor lung function are major causes of public health issues. Emerging evidence suggests adverse exposures even before the conception of a child may cause these conditions. The proposed project is part of an international study across generations to identify these factors. This study will provide novel evidence to guide interventions and identify studies to advance this area further. These original findings will be of great importance both nationally and internationally.
Changing children’s chances: Exploring pathways to developmental inequities. This project aims to investigate the causes of health and developmental inequities between Australian children. Inequities are increasingly observed in Australian children’s physical health, social and emotional wellbeing, and academic learning. Such inequities are unjust, unnecessary and potentially preventable. This project aims to understand the pathways leading to these inequities by examining the many contexts in w ....Changing children’s chances: Exploring pathways to developmental inequities. This project aims to investigate the causes of health and developmental inequities between Australian children. Inequities are increasingly observed in Australian children’s physical health, social and emotional wellbeing, and academic learning. Such inequities are unjust, unnecessary and potentially preventable. This project aims to understand the pathways leading to these inequities by examining the many contexts in which children and their families live and grow. Through a series of innovative analyses using existing data, the project aims to identify potentially modifiable factors at the child, family, school, and community level that contribute to developmental inequities. Understanding of the most promising leverage points for interventions to reduce inequities for Australian children could be used to inform policy.Read moreRead less
Environmental Risk Factors And Genetic Modifiers For Lung Health And Lung Function In A High Risk Cohort
Funder
National Health and Medical Research Council
Funding Amount
$95,348.00
Summary
Asthma is an important determinant of respiratory health and longevity. While early life exposures are thought to be important, the evidence linking them with asthma and lung function is inconclusive. There is a scarcity of longitudinal studies and few investigate genes and environment. This study will determine whether environmental exposures along with their relevant genetic modifiers are related to increased risk of asthma and impaired lung function in a high allergy risk birth cohort.
The Predictors Of Asthma And Lung Function Deficits In The Third Decade: Longitudinal Study Of MACS Sibships
Funder
National Health and Medical Research Council
Funding Amount
$1,176,908.00
Summary
This will be the world’s first birth cohort study to use substantial prospective data to investigate how biological, psychosocial, and environmental markers from birth will predict asthma and lung function in the third decade of life. Our findings will be crucial to the development of new policy and practice for the prevention and management of these conditions and uncover crucial risk factors for young adult asthma.