Identification Of Genes For X-linked Mental Retardation.
Funder
National Health and Medical Research Council
Funding Amount
$675,228.00
Summary
We propose to identify novel heritable causes of intellectual disability using 22 large and well-characterised families from Australia. In these families we have refined the location of the genetic defect to the chromosome X and excluded the contribution of all so far known genes. We will achieve this using the technology of massive parallel sequencing. At the completion of the project we will have identified novel causes of intellectual disability and devised tests to identify them.
Discovery Early Career Researcher Award - Grant ID: DE210100929
Funder
Australian Research Council
Funding Amount
$462,948.00
Summary
Using ancient DNA to uncover climate change impacts on Antarctica. This project aims to utilise ancient DNA preserved in the seafloor to investigate how past Antarctic marine ecosystems have responded to past climatic changes, with a focus on the Holocene (last ~11,700 years). The study will generate the first-ever picture of marine community changes across the entire marine food web and unravel adaptation mechanisms of key marine organisms to climate shifts. Expected project outcomes will inclu ....Using ancient DNA to uncover climate change impacts on Antarctica. This project aims to utilise ancient DNA preserved in the seafloor to investigate how past Antarctic marine ecosystems have responded to past climatic changes, with a focus on the Holocene (last ~11,700 years). The study will generate the first-ever picture of marine community changes across the entire marine food web and unravel adaptation mechanisms of key marine organisms to climate shifts. Expected project outcomes will include significant knowledge advances into the evolution and resilience of Antarctic ecosystems over geological timescales. This will position Australia at the forefront of marine sedimentary ancient DNA research, and also provide valuable guidance for the conservation of Antarctica during ongoing climate change.Read moreRead less
Utilising innovative fishing technology to address key questions on the biology of Antarctic krill. Antarctic krill are an important species in the Southern Ocean supporting most of the Antarctic birds and mammals. A sustainable krill fishery is developing with krill products used in aquaculture and increasingly for human consumption. A new omega 3 krill oil industry has emerged and is rapidly expanding. The aim of the project is to predict the factors governing oil levels and the biochemical co ....Utilising innovative fishing technology to address key questions on the biology of Antarctic krill. Antarctic krill are an important species in the Southern Ocean supporting most of the Antarctic birds and mammals. A sustainable krill fishery is developing with krill products used in aquaculture and increasingly for human consumption. A new omega 3 krill oil industry has emerged and is rapidly expanding. The aim of the project is to predict the factors governing oil levels and the biochemical composition in krill which will help us understand growth, reproduction and recruitment. The research aims to also assess the possible effects of climate change on krill. Outcomes of this research aim to be used to manage the expanding krill fishery.Read moreRead less
The Australian Centre For Research Excellence In Offender Health
Funder
National Health and Medical Research Council
Funding Amount
$2,646,826.00
Summary
Offenders are one of the most marginalised groups in society and endure the worst health outcomes in regards to mental health, exposure to bloodborne viruses and sexually transmissible infections, and engagement in health risk behaviours. Incarceration devastates Indigenous communities and we urgently need for solutions to reduce Aboriginal prisoner numbers. The research proposed by this CRE in mental health and infectious diseases will improve health outcomes for offenders and provide treatment ....Offenders are one of the most marginalised groups in society and endure the worst health outcomes in regards to mental health, exposure to bloodborne viruses and sexually transmissible infections, and engagement in health risk behaviours. Incarceration devastates Indigenous communities and we urgently need for solutions to reduce Aboriginal prisoner numbers. The research proposed by this CRE in mental health and infectious diseases will improve health outcomes for offenders and provide treatment solutions rather than incarceration.Read moreRead less
An investigation of the cognitive processes underlying intrusive traumatic cognition. Intrusive unpleasant thoughts and memories occur in sufferers of anxiety and depression, and are common in normal individuals. Understanding the processes underlying intrusive cognition is critical, especially in the present world climate in which the Australian public is increasingly confronted with threats of terrorism and other negative world events. This research will have the direct benefit of leading to i ....An investigation of the cognitive processes underlying intrusive traumatic cognition. Intrusive unpleasant thoughts and memories occur in sufferers of anxiety and depression, and are common in normal individuals. Understanding the processes underlying intrusive cognition is critical, especially in the present world climate in which the Australian public is increasingly confronted with threats of terrorism and other negative world events. This research will have the direct benefit of leading to improved health of sufferers of anxiety and depression in the Australian community, and has the potential to increase normal individuals' ability to contribute to society by reducing intrusions that can interfere with work productivity, promote absenteeism, and have a negative impact on general wellbeing.Read moreRead less
Diatom lipids to reveal sea-ice history in remote Antarctic regions. This project aims to understand seasonal Antarctic sea-ice extent using molecular, geochemical, elemental and genomic characteristics of specific marine phytoplankton (diatoms). Little is known of the seasonal sea-ice variation and the position of the summer sea-ice extent a million years before satellite records, but this information is critical to determining air-sea gas exchange and ecosystem food web regulation. This projec ....Diatom lipids to reveal sea-ice history in remote Antarctic regions. This project aims to understand seasonal Antarctic sea-ice extent using molecular, geochemical, elemental and genomic characteristics of specific marine phytoplankton (diatoms). Little is known of the seasonal sea-ice variation and the position of the summer sea-ice extent a million years before satellite records, but this information is critical to determining air-sea gas exchange and ecosystem food web regulation. This project will unite geochemical and biological approaches to provide the data to improve past Antarctic ecosystem and climate models where sea-ice data is missing. Studying diatom biomarkers in deep sea cores from Australia’s Southern Ocean will redefine knowledge of Antarctic climate and provide data necessary to improve global ecosystem and climate models.Read moreRead less
Single and dual process models of recognition memory: Reconciliation of behavioural, electrophysiological, and neuroimaging data. Advanced brain scanning technologies are increasingly used to study human memory. As well as being important for our basic understanding of memory, they also tell us how memory is affected by normal development, ageing, disease, and injury. Unfortunately, because these technologies are so new, a gap has opened up between our psychological understanding of memory and t ....Single and dual process models of recognition memory: Reconciliation of behavioural, electrophysiological, and neuroimaging data. Advanced brain scanning technologies are increasingly used to study human memory. As well as being important for our basic understanding of memory, they also tell us how memory is affected by normal development, ageing, disease, and injury. Unfortunately, because these technologies are so new, a gap has opened up between our psychological understanding of memory and the physiological events measured by the scanning technologies. This has created a problem for how we should interpret the results that are found. The present project aims to close this gap by applying new research methodologies and theoretical insights based on our previous research.Read moreRead less
Special Research Initiatives - Grant ID: SR200100005
Funder
Australian Research Council
Funding Amount
$36,000,000.00
Summary
Securing Antarctica's Environmental Future. This program aims to deliver unprecedented research capability for securing Antarctic environments in the face of uncertain change.
By integrating a highly skilled team with new approaches and breakthrough technologies, the program anticipates discovery science, enhanced environmental forecasting and optimised decision-making to advance Australia’s position as an influential Antarctic nation.
Expected outcomes include better environmental management ....Securing Antarctica's Environmental Future. This program aims to deliver unprecedented research capability for securing Antarctic environments in the face of uncertain change.
By integrating a highly skilled team with new approaches and breakthrough technologies, the program anticipates discovery science, enhanced environmental forecasting and optimised decision-making to advance Australia’s position as an influential Antarctic nation.
Expected outcomes include better environmental management, unparalleled strategic decision-support for an effective Antarctic Treaty, and new minds to address Antarctica’s new challenges.
Anticipated benefits are the means to transform environmental forecasting and management in the Antarctic, for Australia, and to the advantage of global security.Read moreRead less
Influences on farmer suicide in Queensland and New South Wales. Australian farmers have been identified as being at high-risk of suicide. This project will provide direction for targeted suicide prevention strategies by quantifying the individual and environmental factors that place farmers at higher risk of suicide, as well as the protective factors that may buffer against suicide and suicidal behaviours.
A 140,000 year insight into the imprint of climate and humans on Australia. Before the arrival of Europeans, two events shaped Australia's current landscapes and biota more than any others: climate change during the glacial cycle and the arrival of humans on the continent. However, the full scale of these events is not well understood. High resolution analyses of two continuous 140 000 year old sediment deposits will be used in this project to fill this void and answer fundamental questions abou ....A 140,000 year insight into the imprint of climate and humans on Australia. Before the arrival of Europeans, two events shaped Australia's current landscapes and biota more than any others: climate change during the glacial cycle and the arrival of humans on the continent. However, the full scale of these events is not well understood. High resolution analyses of two continuous 140 000 year old sediment deposits will be used in this project to fill this void and answer fundamental questions about how current Australian environments came to be.Read moreRead less