Discovery Early Career Researcher Award - Grant ID: DE120101788
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Shape sorting of nanoparticles at oil-water interfaces in microchannels. This project aims to study the effect of shape on the adsorption of nanoparticles at an oil/water interface and develop a rapid, inexpensive, efficient, versatile method for shape sorting of nanoparticles using a microfluidic approach. This technique can be applied for fractionation of synthetic nanoparticles, biosample analysis and environmental monitoring.
Lab-on-a-chip mass spectrometry tools for testing illicit drugs. This project aims to develop fit-for-purpose mass spectrometry tools for roadside and workplace testing of illicit drugs. The technology will be based on nanostructured semiconductor chips that are surface-functionalised to enable molecular capture without extensive sample processing and subsequent detection by a novel combination of techniques. The technology is expected to be applicable to saliva, sweat and urine samples.
Smart hybrid nano-biomaterials that mimic the pharmaceutical food effect. Smart biomaterials will be developed which when taken orally will act in our gut to improve drug and vitamin uptake. The breakthrough science will drive new pharmaceuticals and nutraceuticals for the future health of Australia, and economic benefits will result through increased exposure to the global market for delivering biomolecules.
Discovery Early Career Researcher Award - Grant ID: DE120100042
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Study of oriented attachment of nanocrystals at oil-water interfaces. This project will study the fundamental issues for crystal growth, which will dramatically facilitate the development of effective pathways for the synthesis of advanced nanomaterials for nanodevice and nanotechnology. The obtained outcomes will enhance our knowledge in crystal growth and colloid sciences.
Forensic platform technologies for roadside and workplace testing based on nanostructured silicon chips. Roadside drug testing has recently been incorporated into government legislation throughout Australia and abroad. The objective of this project is to develop advanced analysis technologies for implementing effective roadside and workplace testing. The availability of these technologies will increase the safety of Australian drivers and workers.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100193
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Super High Resolution Correlative Microscopy: New Research Capability for Bioengineering, Clean Energy, Mineral Processing and Environmental Sciences. Super high resolution correlative microscopy: new research capability for bioengineering, clean energy, mineral processing and environmental sciences: This project will establish the first facility for super high resolution correlative microscopy in Australia. This facility will underpin breakthrough science by providing the capability to combine ....Super High Resolution Correlative Microscopy: New Research Capability for Bioengineering, Clean Energy, Mineral Processing and Environmental Sciences. Super high resolution correlative microscopy: new research capability for bioengineering, clean energy, mineral processing and environmental sciences: This project will establish the first facility for super high resolution correlative microscopy in Australia. This facility will underpin breakthrough science by providing the capability to combine and overlay conventional and super high resolution light microscopy information with electron microscopy information on identical sample locations. This new capability will foster advances in the fundamental understanding of multiscale hybrid organic and inorganic structures and spur the development of advanced (nano)materials and devices with broad applications in bioengineering and biofouling, advanced materials for life sciences, clean energy, water and the environment and mineral processing.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101044
Funder
Australian Research Council
Funding Amount
$444,318.00
Summary
Bio-inspired nanomaterials with tunable drug loading and controlled release. This project aims to develop new platform technologies for making bio-inspired nanomaterials with tunable drug loading and controlled release. This project will revolutionise current approaches to make lipid nanoparticles camouflaged with natural cell membranes for delivery of both insoluble and soluble drugs. Significant outcomes will include a novel commercially relevant salt-induced nanoprecipitation platform technol ....Bio-inspired nanomaterials with tunable drug loading and controlled release. This project aims to develop new platform technologies for making bio-inspired nanomaterials with tunable drug loading and controlled release. This project will revolutionise current approaches to make lipid nanoparticles camouflaged with natural cell membranes for delivery of both insoluble and soluble drugs. Significant outcomes will include a novel commercially relevant salt-induced nanoprecipitation platform technology for making precisely engineered nanomaterials with tailored functions for applications in controlled release and targeted delivery. Benefits include securing a sustainable future for Australia, with new nanotechnology strategies for advanced manufacturing.Read moreRead less
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Harnessing lipid nano-assembly for next generation functional foods and pharmaceutical products. Nature assembles lipid molecules from our diet into useful structures in our gastrointestinal tract with remarkable precision and versatility. By understanding and harnessing these processes we can design new lipid-based nanomaterials leading to more effective functional foods and pharmaceutical products with reduced side effects.