Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome proje ....Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome project, major opportunities exist to provide spectacular advances in human health care (eg, via personalised medicine) provided that appropriate high-throughput biological reading devices can be developed. In developing such devices, this project also aims to substantially catalyse the Australian Nanotechnology/Biotechnology industry.Read moreRead less
Numerical Modelling and Experimental Studies to Design and Engineer Nanoparticulate Systems for Bioapplications. Project outcomes will enhance Australia's reputation for scientific innovation in the field of bio-nanotechnology. The project will expand the knowledge base in this area and increase Australia's international profile in research on nanomaterials for bio-related applications. The project partners UNSW and Australian company (Minomic), integrating their skills, expertise and facilities ....Numerical Modelling and Experimental Studies to Design and Engineer Nanoparticulate Systems for Bioapplications. Project outcomes will enhance Australia's reputation for scientific innovation in the field of bio-nanotechnology. The project will expand the knowledge base in this area and increase Australia's international profile in research on nanomaterials for bio-related applications. The project partners UNSW and Australian company (Minomic), integrating their skills, expertise and facilities to address current limitations in understanding the stability of magnetic nanoparticles in biological fluids. The Australian partners will play a leading role in commercializing new applications for functionalized magnetic nanoparticles. The project will provide an excellent multidisciplinary research environment and training for early career researchers.Read moreRead less
Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk ass ....Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk assessment. This is intended to be achieved by developing and validating high-throughput in vitro toxicity screening platforms for manufactured nanoparticles. The approach is based on advanced lab-on-a-chip microfluidic technologies. The predictive power of the platform will be refined and optimised via ex-vivo and in-vivo models.Read moreRead less
Band-Gap Engineered Visible Light Photocatalysts: Enabling Technologies for Sustainable Energy and the Environment. This program will contribute significantly to knowledge advancement in colloid chemistry, nanomaterials and electrochemistry, and is firmly embedded in the National Research Priorities of Frontier Science and an Environmentally Sustainable Australia. In particular, it addresses the goals of water and low emission energy supply. The outcomes of this research will advance a new class ....Band-Gap Engineered Visible Light Photocatalysts: Enabling Technologies for Sustainable Energy and the Environment. This program will contribute significantly to knowledge advancement in colloid chemistry, nanomaterials and electrochemistry, and is firmly embedded in the National Research Priorities of Frontier Science and an Environmentally Sustainable Australia. In particular, it addresses the goals of water and low emission energy supply. The outcomes of this research will advance a new class of visible-light active photocatalysts that underpin the development of hydrogen generation, low cost solar cells and water purification using sunlight. Such technologies will transform the Australian energy and environmental industries and speed up the transition from a fossil fuel economy to a renewable energy economy.Read moreRead less
Tailoring nano-crystal suspensions for extended ion supply to hydrophobic and hydrophilic leaf surfaces. Nutrient deficiency undermines the potential of billions of people and many nations. The requirement is to rapidly increase micro-nutrient delivery to support intensive and fortified crop production. This proposal seeks to develop a controlled ion release system through the use of tailored suspensions of nano-crystal nutrient materials for delivery to plants through the leaves. This will incr ....Tailoring nano-crystal suspensions for extended ion supply to hydrophobic and hydrophilic leaf surfaces. Nutrient deficiency undermines the potential of billions of people and many nations. The requirement is to rapidly increase micro-nutrient delivery to support intensive and fortified crop production. This proposal seeks to develop a controlled ion release system through the use of tailored suspensions of nano-crystal nutrient materials for delivery to plants through the leaves. This will increase yields from arable land, reduce water requirements and fertiliser applications, fortifying foods for better nutrition leading to improved human health and wellbeing. It leverages and applies recent significant advances in surface science and nanotechnology to gain improved outcomes in agriculture.Read moreRead less
Charge-driven self-assembly of nanocomposites of ionic polymers and oxide nanoparticles. This project addresses the materials needs in platform technologies for more efficient and cleaner means of generating energy and utilising energy. It also aims at better catalysts for cleaner chemical processes. The novel nanocomposites with significantly increased active ionic sites and higher ionic conductivity, and better activity in catalysis will lead to possible new breakthroughs in technologies for e ....Charge-driven self-assembly of nanocomposites of ionic polymers and oxide nanoparticles. This project addresses the materials needs in platform technologies for more efficient and cleaner means of generating energy and utilising energy. It also aims at better catalysts for cleaner chemical processes. The novel nanocomposites with significantly increased active ionic sites and higher ionic conductivity, and better activity in catalysis will lead to possible new breakthroughs in technologies for energy, environmental and self-cleaning materials. The fabrication approach developed are also applicable to other functional nanomaterials, providing new opportunities for innovative nanotechnology to clearer and greener chemical and energy industries.
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Fundamental Characterization of Adsorption of Simple to Complex Fluids on Carbon Black and in Carbon Pores. The outcome of this project will help designing engineers with a molecular simulation model for adsorption of simple to complex fluids commonly used in industries. The success of this project translates to a significant saving because it requires minimum effort in experimentation.
Methane hydrate in carbon nanopores as a potential means for energy storage. This project deals with the innovative means to store methane (natural gas) in the form of methane hydrate in the nanospace of carbon pores. The significance of this project lies in the enhanced storage of methane at a moderate pressure, compared to the compressed natural gas technology. Expected outcome is the better and efficient utilization of natural gas in transportation industries, and the better understanding o ....Methane hydrate in carbon nanopores as a potential means for energy storage. This project deals with the innovative means to store methane (natural gas) in the form of methane hydrate in the nanospace of carbon pores. The significance of this project lies in the enhanced storage of methane at a moderate pressure, compared to the compressed natural gas technology. Expected outcome is the better and efficient utilization of natural gas in transportation industries, and the better understanding of the formation of methane hydrate in carbon nanopores.Read moreRead less
Multimodal biomedical imaging probes: development of advanced polymer nanocomposite devices for oncology. Despite significant research being directed toward cancer treatment, 7.6 million people died world wide in 2007. Early detection and treatment is widely recognised as being effective in significantly reducing mortality rates. Biomedical imaging techniques are routinely used for detection and staging of many cancers. However, greater sensitivity is required so that these techniques can be app ....Multimodal biomedical imaging probes: development of advanced polymer nanocomposite devices for oncology. Despite significant research being directed toward cancer treatment, 7.6 million people died world wide in 2007. Early detection and treatment is widely recognised as being effective in significantly reducing mortality rates. Biomedical imaging techniques are routinely used for detection and staging of many cancers. However, greater sensitivity is required so that these techniques can be applied to very early detection of tumours. To overcome this short-coming the next generation of imaging probes will be developed, which will require fundamental investigations in polymer and nanomaterials science to maximise imaging sensitivity and extend probe functionality. Successful outcomes will lead to significant benefits to healthcare in Australia.Read moreRead less