Centre Of Research Excellence In Medicines And Ageing
Funder
National Health and Medical Research Council
Funding Amount
$2,601,415.00
Summary
Medicines have an important place in health and are commonly used for long periods, sometimes life-long. Using medicines wisely requires a careful balance between benefits and harmful effects. Currently, there is limited information to guide medicines use over a lifetime. Using large linked datasets, the CRE in Medicines and Ageing will generate much needed evidence about real world medicines use to support clinical and pharmaceutical policy decisions.
Protecting Critical Transport Infrastructure using Hybrid Approaches for Interference and Spoofer Detection and Localisation. Modern infrastructure increasingly relies on the positioning and timing capabilities provided by the Global Navigation Satellite Systems (GNSS). GNSS signals, however, are vulnerable to interference and spoofing attacks. This vulnerability is aggravated as satellite navigation becomes more central to the operation of airports, ports, railways, and communications systems. ....Protecting Critical Transport Infrastructure using Hybrid Approaches for Interference and Spoofer Detection and Localisation. Modern infrastructure increasingly relies on the positioning and timing capabilities provided by the Global Navigation Satellite Systems (GNSS). GNSS signals, however, are vulnerable to interference and spoofing attacks. This vulnerability is aggravated as satellite navigation becomes more central to the operation of airports, ports, railways, and communications systems. Building on from earlier work by University of New South Wales, University of Adelaide and GPSat Systems, this project aims to create a system for locating interference and spoofers to GNSS of any power in real time, providing layered monitoring and reactive mitigation solutions against interference and spoofing attacks.Read moreRead less
Development of a Prothrombogenic Bone Graft Substitute. The clinical demand for bone is massive and to counter this bone can be either harvested from the patient or bone substitutes are used. The success or failure of a bone substitute is determined the instant it come into contact with blood. The surfaces of traditional biomaterials induce a foreign body reaction. The aim of this project is to test the bone forming capacity of a biomaterial that is optimised to produce a natural response from ....Development of a Prothrombogenic Bone Graft Substitute. The clinical demand for bone is massive and to counter this bone can be either harvested from the patient or bone substitutes are used. The success or failure of a bone substitute is determined the instant it come into contact with blood. The surfaces of traditional biomaterials induce a foreign body reaction. The aim of this project is to test the bone forming capacity of a biomaterial that is optimised to produce a natural response from the blood. This response will lead to the formation new viable tissue and eventually bone. Such a material will cause faster bone healing, less pain from graft sites, shorter hospital stays and shorter waiting lists. Read moreRead less
Development of a Light-Activated Bioadhesive for Low Temperature Tissue Repair. While sutures currently represent the gold standard for wound closure, their fundamental technology has changed little in thousands of years. Surgical sealants and energy based closure devices are expected to increasingly replace or complement sutures, improving tissue closure and wound healing. The innovative research in this proposal will develop the next generation of surgical bioadhesive technology and claim a s ....Development of a Light-Activated Bioadhesive for Low Temperature Tissue Repair. While sutures currently represent the gold standard for wound closure, their fundamental technology has changed little in thousands of years. Surgical sealants and energy based closure devices are expected to increasingly replace or complement sutures, improving tissue closure and wound healing. The innovative research in this proposal will develop the next generation of surgical bioadhesive technology and claim a stake in the estimated US$ 4 billion market. The project outcomes will enhance Australia's reputation in the biomedical field and will have world-wide social and health care benefits by ultimately allowing better functional healing through bioadhesives that can be effectively applied rapidly and consistently.Read moreRead less
The mechanics of being human. This project will lead to far more detailed understanding of skull mechanics in our own lineage. Results will be of great interest to international scholars in both evolutionary and biomedical fields and help to establish a primary position for Australia in the rapidly expanding area of computer simulation of biological structure. Further development on our own established protocols for automated transfer of CT scan data into finite element models, which have alread ....The mechanics of being human. This project will lead to far more detailed understanding of skull mechanics in our own lineage. Results will be of great interest to international scholars in both evolutionary and biomedical fields and help to establish a primary position for Australia in the rapidly expanding area of computer simulation of biological structure. Further development on our own established protocols for automated transfer of CT scan data into finite element models, which have already improved speed, accuracy and realism, will take finite element analysis to a point at which it can be more readily applied to evolutionary, biomedical and safety design questions.Read moreRead less
ANATOMICAL ORGAN MODELLING AND SURGICAL PROCEDURE SIMULATION FOR THORACOSCOPIC SURGERY. We aim to establish novel virtual reality-based surgical procedure simulation methodologies, geometric and physical models of human organs, and surgical tools and interaction modules for thoracoscopic surgery or for minimally invasive surgical procedures. This is needed to optimize surgical strategy and to anticipate possible problems that may arise during the procedure, and to train medical staff as the tren ....ANATOMICAL ORGAN MODELLING AND SURGICAL PROCEDURE SIMULATION FOR THORACOSCOPIC SURGERY. We aim to establish novel virtual reality-based surgical procedure simulation methodologies, geometric and physical models of human organs, and surgical tools and interaction modules for thoracoscopic surgery or for minimally invasive surgical procedures. This is needed to optimize surgical strategy and to anticipate possible problems that may arise during the procedure, and to train medical staff as the trend towards robotic-assisted minimally invasive surgery continues. What makes this project novel is the anatomical organ modeling approach based on virtual springs and dampers traversing between the top and bottom surfaces of the organs and tissues, contrary to previous approaches.Read moreRead less
Situational Assessment as a Marker of Cognitive Skill Decay. The aim of this study is to test how differences in exposure to complex tasks change the capacity for situational assessment. Amongst drivers, pilots and electricity controllers, the capacity to assess and respond effectively to changes in the operational environment are critical in sustaining performance and ensuring the safety and security of the public. Establishing the nature of this relationship will enable, for the first time, ob ....Situational Assessment as a Marker of Cognitive Skill Decay. The aim of this study is to test how differences in exposure to complex tasks change the capacity for situational assessment. Amongst drivers, pilots and electricity controllers, the capacity to assess and respond effectively to changes in the operational environment are critical in sustaining performance and ensuring the safety and security of the public. Establishing the nature of this relationship will enable, for the first time, objective measures of cognitive skill decay. In evaluating cognitive skill decay more accurately, we will provide a cost-effective, easily administered tool, enabling practitioners to identify and address areas of development and providing data to anticipate when cognitive skill decay is most likely to occur.Read moreRead less
Fracture Associated Premature Mortality; An International Consortium
Funder
National Health and Medical Research Council
Funding Amount
$579,807.00
Summary
Following an osteoporotic fracture there is an increased premature mortality compared with someone who has not fractured. There is also evidence that anti-osteoporosis medication reduces this premature mortality. This study will determine the size of the fracture-mortality relationship and the effect of treatment on this mortality for different fracture types and in different populations by integrating data from multiple international epidemiology studies of osteoporosis.
Dynamic Rollover Occupant Protection (DROP): evaluation and regulation. This projects seeks to establish which occupant crashworthiness attributes a vehicle must possess to prevent injury in a rollover crash. The results will assist regulators, industry and consumer groups understand which critical factors need to be considered to develop rollover crashworthiness regulations, consumer tests and vehicle purchase policy.
Industrial Transformation Training Centres - Grant ID: IC160100025
Funder
Australian Research Council
Funding Amount
$2,259,000.00
Summary
ARC Training Centre in Food Safety in the Fresh Produce Industry. ARC Training Centre in Food Safety in the Fresh Produce Industry. This centre aims to create an innovation platform of food safety researchers and industry personnel who can significantly advance the safety of fruit and vegetables in Australia. The intended outcomes are safer food, leading to enhanced health and wellbeing; industry growth in the food/agribusiness sector; enhanced trust and international reputation; and increased a ....ARC Training Centre in Food Safety in the Fresh Produce Industry. ARC Training Centre in Food Safety in the Fresh Produce Industry. This centre aims to create an innovation platform of food safety researchers and industry personnel who can significantly advance the safety of fruit and vegetables in Australia. The intended outcomes are safer food, leading to enhanced health and wellbeing; industry growth in the food/agribusiness sector; enhanced trust and international reputation; and increased access to growing export markets. Intended benefits to industry are ready-to-use technologies for strengthened food safety, and a new generation of highly-skilled food safety scientists with experience in conducting industry-focused research.Read moreRead less