Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100137
Funder
Australian Research Council
Funding Amount
$881,758.00
Summary
Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-fun ....Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-funded resource for integrated exposure research into the future. The archive is expected to support longitudinal and cross-sectional studies to assess trends in exposure to chemical and biological hazards in the Australian population, identify emerging hazards, and provide a scientific basis for policy and regulatory actions.Read moreRead less
Realistic assessment of biomarker transformation in the wastewater system. Wastewater-based epidemiology is an internationally recognised cost-effective tool to monitor population exposure to chemicals and infectious diseases including Covid-19. However, in-sewer degradation of critical biomarkers can limit their wastewater-based epidemiology suitability. This project aims to systematically evaluate the stability of a new suite of potential biomarkers and conduct the first Australia-wide assessm ....Realistic assessment of biomarker transformation in the wastewater system. Wastewater-based epidemiology is an internationally recognised cost-effective tool to monitor population exposure to chemicals and infectious diseases including Covid-19. However, in-sewer degradation of critical biomarkers can limit their wastewater-based epidemiology suitability. This project aims to systematically evaluate the stability of a new suite of potential biomarkers and conduct the first Australia-wide assessment on the impact of biomarker stability on wastewater-based epidemiology estimates using wastewater samples from ~65% of the Australian population. The project expects to generate knowledge to expand the application of wastewater-based epidemiology to reliably quantify exposure and status of well-being even in remote areasRead moreRead less
Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alter ....Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alternative nicotine products. The outcomes of this project will provide reliable, cost-effective estimates of tobacco consumption for use with wastewater-based epidemiology assessments. This will enable changes in tobacco use to be accurately evaluated for the first time and improve the efficacy of tobacco control measures.Read moreRead less