Electric field effects on cochlear tissues. The project aims to solve the underlying biology of how electricity flows through the cochlear tissues, where and how electrical stimulation excites the auditory neurons, and what the effects of sustained electrical stimulation are on the nerve fibre growth and function. The research aims to show how electric fields can be controlled in the cochlea, and how auditory nerve fibres are affected at the cellular and molecular level. The long-term aim is to ....Electric field effects on cochlear tissues. The project aims to solve the underlying biology of how electricity flows through the cochlear tissues, where and how electrical stimulation excites the auditory neurons, and what the effects of sustained electrical stimulation are on the nerve fibre growth and function. The research aims to show how electric fields can be controlled in the cochlea, and how auditory nerve fibres are affected at the cellular and molecular level. The long-term aim is to utilise these findings to improve the control of neuronal excitability, for development of interfaces with the nervous system.Read moreRead less
Understanding plant uptake of organic and inorganic nitrogen for optimal fertiliser application in forestry. Nitrogen (N) in soils occurs in both organic and inorganic forms. Plants can take up inorganic N - nitrate and ammonium - but, on average, these account for only 5% of the soluble N in soils. Recent evidence suggests that plants may be able to tap into some of the 95% of N that occurs in organic forms. We will investigate the importance of organic N uptake for two plantation Eucalyptus sp ....Understanding plant uptake of organic and inorganic nitrogen for optimal fertiliser application in forestry. Nitrogen (N) in soils occurs in both organic and inorganic forms. Plants can take up inorganic N - nitrate and ammonium - but, on average, these account for only 5% of the soluble N in soils. Recent evidence suggests that plants may be able to tap into some of the 95% of N that occurs in organic forms. We will investigate the importance of organic N uptake for two plantation Eucalyptus species by tracing the uptake of different N forms by bacteria, fungi and eucalypts. This information will redefine what is meant by 'available N' and will guide the development of a new test for soil N status.Read moreRead less
Transport systems that underpin nitrogen efficient maize. This project aims to define the nitrogen transport network involved in the uptake, storage and redistribution of inorganic nitrogen (nitrate and ammonium) over the developmental life cycle of maize. This information will provide novel insight into the genetic control of nitrogen use in maize and other cereal crops.
Nutritional and bacterial influences on gut and peripheral homeostasis. Nutritional and bacterial influences on gut and peripheral homeostasis. This project aims to understand the role of macronutrients on gut homeostasis. While the understanding of what factors affect gut homeostasis is still in its infancy, scientists know that its disruption contributes to a broad range of inflammatory diseases, including type 1 diabetes and asthma. This project will determine the role of specific macronutrie ....Nutritional and bacterial influences on gut and peripheral homeostasis. Nutritional and bacterial influences on gut and peripheral homeostasis. This project aims to understand the role of macronutrients on gut homeostasis. While the understanding of what factors affect gut homeostasis is still in its infancy, scientists know that its disruption contributes to a broad range of inflammatory diseases, including type 1 diabetes and asthma. This project will determine the role of specific macronutrients on gut microbiota, gut epithelium, and immunity in mice, and the receptors involved. This research could ultimately lead to significant decreases in the cost of healthcare.Read moreRead less
Use of Gradipore technology to develop novel methods for the preparation and segregation of mammalian spermatozoa. The purpose of this project is to harness the expertise available within an Australian biotechnology company, Gradipore, to develop novel methods for the preparation of mammalian spermatozoa and the segregation of these cells into X-and Y- bearing populations. This technology will find application in: (1)clinical andrology, where rapid, safe protocols for the preparation and segrega ....Use of Gradipore technology to develop novel methods for the preparation and segregation of mammalian spermatozoa. The purpose of this project is to harness the expertise available within an Australian biotechnology company, Gradipore, to develop novel methods for the preparation of mammalian spermatozoa and the segregation of these cells into X-and Y- bearing populations. This technology will find application in: (1)clinical andrology, where rapid, safe protocols for the preparation and segregation of human spermatozoa are being actively sought in the context of assisted conception and the management of sex-linked genetic diseases and (2) agriculture, particularly the cattle industry, where a capacity to predetermine the sex of the offspring would be extremely valuable.Read moreRead less
Evaluating the effects of fipronil, a moderately persistent new generation pesticide, on Australian native vertebrates. The Australian Plague Locust Commission is considering replacing an organophosphate pesticide with fipronil, a relatively new phenyl pyrazole pesticide, because it more specifically targets invertebrate animals. However, fipronil is more environmentally persistent, has high lipid solubility, is known to disrupt thyroid function and has wide variation in its toxicity to vertebra ....Evaluating the effects of fipronil, a moderately persistent new generation pesticide, on Australian native vertebrates. The Australian Plague Locust Commission is considering replacing an organophosphate pesticide with fipronil, a relatively new phenyl pyrazole pesticide, because it more specifically targets invertebrate animals. However, fipronil is more environmentally persistent, has high lipid solubility, is known to disrupt thyroid function and has wide variation in its toxicity to vertebrates . These characteristics place native vertebrate species at risk. Further, because peak locust activity is coincident with vertebrate breeding, there is likelihood that fipronil will affect development of young and the health of adults. We propose to launch the first comprehensive study of fipronil's effects on the health and vitality of native vertebrate adults and their offspring. We will focus on dasyurid marsupials and native birds that co-occur with plague locusts.Read moreRead less
QX DISEASE RESISTANCE IN SYDNEY ROCK OYSTERS. QX is a fatal disease of Sydney rock oysters. The protozoan parasite that causes QX has been identified in more than one third of oyster farming areas on the east coast of Australia. Disease outbreaks have already destroyed the oyster industry in some of those areas. This project tests whether a novel form of defensive protein that has been identified in some oysters can be used as a genetic marker of QX disease resistance. The selective breeding of ....QX DISEASE RESISTANCE IN SYDNEY ROCK OYSTERS. QX is a fatal disease of Sydney rock oysters. The protozoan parasite that causes QX has been identified in more than one third of oyster farming areas on the east coast of Australia. Disease outbreaks have already destroyed the oyster industry in some of those areas. This project tests whether a novel form of defensive protein that has been identified in some oysters can be used as a genetic marker of QX disease resistance. The selective breeding of disease resistant oysters based on such a genetic marker would help to control QX and secure the future of Australia's rock oyster industry.Read moreRead less
Soil physical limitations to growth in sub-tropical hardwood plantations. Large areas of eucalypt plantations are being established to replace native forest wood production in many areas of Australia. A major impediment facing the industry in subtropical eastern Australia is inappropriate site species matching. This is largely due to lack of understanding of the major soil types in the region and the effect on growth of different species. This project will compare site productivity and soil ch ....Soil physical limitations to growth in sub-tropical hardwood plantations. Large areas of eucalypt plantations are being established to replace native forest wood production in many areas of Australia. A major impediment facing the industry in subtropical eastern Australia is inappropriate site species matching. This is largely due to lack of understanding of the major soil types in the region and the effect on growth of different species. This project will compare site productivity and soil characteristics in two major hardwood species and investigate fundamental relationships between soil characteristics and tree root growth. The outcome will be a mechanistic understanding of soil physical limitations to tree growth.Read moreRead less
Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild ba ....Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild barley and identify appropriate candidate genes and their position on chromosomes for further incorporating these traits into commercial barley cultivars. This will reduce the environmental footprint of modern agricultural practices on terrestrial and aquatic ecosystems without compromising food security.Read moreRead less
Mixed species plantations: does diversity help tropical eucalypts grow faster, better, longer? To test the assumption that mixtures are better than monocultures, using data from experiments (QFRI) and community plantings. Growth rate, habit (form, branching), timber and soil characteristics in Eucalyptus pellita (Red Mahogany) plantings should elucidate whether mixtures:
1. grow (above-ground woody biomass) faster than pure plantings;
2. have straighter trees with smaller branches;
3. improve ....Mixed species plantations: does diversity help tropical eucalypts grow faster, better, longer? To test the assumption that mixtures are better than monocultures, using data from experiments (QFRI) and community plantings. Growth rate, habit (form, branching), timber and soil characteristics in Eucalyptus pellita (Red Mahogany) plantings should elucidate whether mixtures:
1. grow (above-ground woody biomass) faster than pure plantings;
2. have straighter trees with smaller branches;
3. improve soil fertility; and whether
4. differences are accentuated in subsequent rotations.
E. pellita has valuable dark-red timber, and is widely planted in north Queensland, despite variable performance (3-30 m3/ha/yr, average 10m3/ha/yr). Analyses will reveal opportunities for conservation outcomes and sustainable timber production.Read moreRead less