Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cos ....Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cost, portable devices for the analysis of exosomes and exosomal miRNA in biological samples. The future development of this technology into diagnostic devices will improve patient outcomes by enabling earlier disease diagnosis and improved monitoring of treatment.Read moreRead less
Engineering two dimensional polymers for membrane-based chemical separation. This project aims to develop novel two-dimensional polymers with precisely controlled pore-sizes for preparing membrane materials which can efficiently separate these gaseous chemicals at ambient temperatures. Key industrial chemical mixtures with similar size and boiling points are difficult to separate by conventional distillation methods. Currently, purification of olefins alone accounts for 0.3% of global energy use ....Engineering two dimensional polymers for membrane-based chemical separation. This project aims to develop novel two-dimensional polymers with precisely controlled pore-sizes for preparing membrane materials which can efficiently separate these gaseous chemicals at ambient temperatures. Key industrial chemical mixtures with similar size and boiling points are difficult to separate by conventional distillation methods. Currently, purification of olefins alone accounts for 0.3% of global energy use. The expected outcomes of the project will have a huge impact on industrial purification processing by providing a disruptive membrane technology, and will significantly reduce energy consumption and open up new routes for resources.Read moreRead less
Polymer nanodiscs. This project aims to produce disc-shaped polymer nanomaterials by utilising a new self-assembly concept based on oppositely charged polymers. This project expects to generate a modular technology that allows synthesis and control over the geometry and functionality of polymer nanoparticles. This level of control will permit a precise investigation of polymer nanodisc properties for nanomedicine applications. Expected outcomes of this project will be the fundamental understandi ....Polymer nanodiscs. This project aims to produce disc-shaped polymer nanomaterials by utilising a new self-assembly concept based on oppositely charged polymers. This project expects to generate a modular technology that allows synthesis and control over the geometry and functionality of polymer nanoparticles. This level of control will permit a precise investigation of polymer nanodisc properties for nanomedicine applications. Expected outcomes of this project will be the fundamental understanding of how nanoparticle geometry affects particle-cell interaction and how nanoscale polymer discs can be used to mimic biological nanoparticles in shape and function.Read moreRead less