The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
Variation in the arginine vasopressin 1a receptor (AVPR1a) gene, the social environment, general health and wellbeing. The project aims to investigate how the arginine vasopressin 1a gene affects gene expression and influences social behaviour and ultimately health and wellbeing. This research will contribute to understanding the importance of individual differences in social policy and interventions aimed at improving health and wellbeing.
A theory of communicative practices within financial internet discussion site communities. This project aims to use online financial investment communities to identify factors that drive communication and influence knowledge co-creation, examine how systematic variations in these factors influence investor decision making, and develop a mid-range theory for explaining and predicting the influence of online communication patterns on individual decisions and market outcomes. By developing and vali ....A theory of communicative practices within financial internet discussion site communities. This project aims to use online financial investment communities to identify factors that drive communication and influence knowledge co-creation, examine how systematic variations in these factors influence investor decision making, and develop a mid-range theory for explaining and predicting the influence of online communication patterns on individual decisions and market outcomes. By developing and validating a new mid-range theory, initially in the financial investment context, this project will provide significant benefits, such as help to secure Australia’s place in a changing world through improved information flow.Read moreRead less
The 2004 Australian Election Study Survey: The Decline of Political Parties? Long renowned for the stability of its political party system, Australia is finally experiencing a sustained challenge to the dominance of the major parties, which is reflected in an increasing preference by voters for minor parties and independent candidates. This project will examine the implications of these developments by conducting a public-use, national sample survey of voters at the next federal election, likely ....The 2004 Australian Election Study Survey: The Decline of Political Parties? Long renowned for the stability of its political party system, Australia is finally experiencing a sustained challenge to the dominance of the major parties, which is reflected in an increasing preference by voters for minor parties and independent candidates. This project will examine the implications of these developments by conducting a public-use, national sample survey of voters at the next federal election, likely to be held in 2004. The outcomes generated by the project will enhance academic and community understanding of the nature of the changing partisan climate within the Australian electorate.Read moreRead less
The law of deliberative democracy: theory and reform. Deliberation is essential to the health of electoral and representative democracy. This project will evaluate and recommend the reform of the law underpinning democratic politics in Australia, to enhance its deliberative quality.
The role of short tandem repeat DNA variation in the evolution of human psychological diversity. The proposed work addresses fundamental questions about human nature. It ties together the evolutionary processes that have shaped us as a species with the way our genes influence: our personalities, the way we think and how we behave. It introduces a novel approach to addressing questions about the role of genetics in human variation that will contribute substantially to the way we understand, perce ....The role of short tandem repeat DNA variation in the evolution of human psychological diversity. The proposed work addresses fundamental questions about human nature. It ties together the evolutionary processes that have shaped us as a species with the way our genes influence: our personalities, the way we think and how we behave. It introduces a novel approach to addressing questions about the role of genetics in human variation that will contribute substantially to the way we understand, perceive and manage important aspects of human diversity.Read moreRead less
A systems approach to dissect the pathogenicity and host specificity of the Fusarium wilt pathogen, Fusarium oxysporum. The pathogenic fungus Fusarium oxysporum causes wilt disease in many plant species, including many that are important for Australian agriculture. Developing environmentally friendly disease protection strategies against this pathogen requires a clear understanding of infection strategies used by the fungus to invade its host. This project, along with a parallel project in host ....A systems approach to dissect the pathogenicity and host specificity of the Fusarium wilt pathogen, Fusarium oxysporum. The pathogenic fungus Fusarium oxysporum causes wilt disease in many plant species, including many that are important for Australian agriculture. Developing environmentally friendly disease protection strategies against this pathogen requires a clear understanding of infection strategies used by the fungus to invade its host. This project, along with a parallel project in host resistance mechanisms, will provide the basis for development of a world leading platform in mechanisms of fungal pathogenicity and virulence and plant disease resistance/susceptibility. Application of the knowledge gained in this project to other host-pathogen interactions will thereby provide opportunities for improved crop protection and biosecurity.Read moreRead less
Radical right populist parties. This project aims to explain why some radical right-wing populists in Western democracies enter governmental alliances with mainstream parties while others remain isolated. The emergence, spread and electoral success of radical right populists is a problem facing liberal democracy in the twenty-first century. While these parties’ policies, ideologies and rhetoric are similar, their relationships with mainstream parties are different. By examining explanatory facto ....Radical right populist parties. This project aims to explain why some radical right-wing populists in Western democracies enter governmental alliances with mainstream parties while others remain isolated. The emergence, spread and electoral success of radical right populists is a problem facing liberal democracy in the twenty-first century. While these parties’ policies, ideologies and rhetoric are similar, their relationships with mainstream parties are different. By examining explanatory factors that Political Science studies have so far been neglected, this project seeks to explain this variation and explore its implications for coalition theory.Read moreRead less
View-based processing of pattern matching queries in large graphs. Graph data exist ubiquitously in modern information systems. Graph pattern matching (GPM) finds parts of the data graph that match a given pattern. It has applications in many areas including knowledge discovery, public health, and crime detection. This project will develop novel techniques for the efficient processing of GPM queries in large graphs.
The 2012/13 Australian Election Study: volatility and electoral change. The 2012/13 Australian Election Study will provide both an in-depth understanding of general patterns of voting behaviour and a detailed, objective account of how and why voters made up their minds in this federal election. The study adds to the unbroken series of national surveys conducted after each Australian federal election since 1987.