The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
Preventing railway suicide: An open-systems perspective. Preventing railway suicide: An open-systems perspective. This project aims to develop an automated suicide risk detection system to reduce the incidence and impact of railway suicide, which has a devastating effect on victims’ families, station staff, train drivers, emergency workers, and bystanders. This project will use open-systems theory to develop two complementary information systems for more effective detection and reporting of suic ....Preventing railway suicide: An open-systems perspective. Preventing railway suicide: An open-systems perspective. This project aims to develop an automated suicide risk detection system to reduce the incidence and impact of railway suicide, which has a devastating effect on victims’ families, station staff, train drivers, emergency workers, and bystanders. This project will use open-systems theory to develop two complementary information systems for more effective detection and reporting of suicide risk; use these systems to investigate how different situational factors interact with different combinations of service interventions to influence suicide risk; and share the findings to reduce railway suicide in Australia and overseas.Read moreRead less
Digital nomadism: How IT enables new forms of working and organising. This project aims to gain a better understanding of digital nomadism. Digital nomads use IT platforms to work remotely over the Internet while perpetually travelling. The project will develop new knowledge by better understanding of how IT transforms work and enable digital nomadism, the motivations and values of workers and their clients/organisations engaged in digital nomadism and the implications and consequences of digita ....Digital nomadism: How IT enables new forms of working and organising. This project aims to gain a better understanding of digital nomadism. Digital nomads use IT platforms to work remotely over the Internet while perpetually travelling. The project will develop new knowledge by better understanding of how IT transforms work and enable digital nomadism, the motivations and values of workers and their clients/organisations engaged in digital nomadism and the implications and consequences of digital nomadism for workers and clients/organisations. The project is expected to have a significant impact on policy and public discourse by providing an in-depth explanation and understanding of digital nomadism based on rigorous research.Read moreRead less
Transforming Microgrid to Virtual Power Plant –ICT Frameworks,Tools,Control. The project aims to enhance large scale renewable penetrations to national power grid by advancing control, optimization, and ancillary services of Virtual Power Plants (VPPs), considering different disruptive events including recent South Australian blackout. This project expects to create new control, frame communication architecture, develop plug and play type IoT enabled grid interfacing inverter, and optimize resou ....Transforming Microgrid to Virtual Power Plant –ICT Frameworks,Tools,Control. The project aims to enhance large scale renewable penetrations to national power grid by advancing control, optimization, and ancillary services of Virtual Power Plants (VPPs), considering different disruptive events including recent South Australian blackout. This project expects to create new control, frame communication architecture, develop plug and play type IoT enabled grid interfacing inverter, and optimize resource management for distributed VPPs. The anticipated benefits from this institutional level collaborations are that VPPs help in enhancing national power grid operations during normal and disruptive conditions when more renewables are connected and also secure benefits of consumers, prosumers, and grid operators.Read moreRead less
Flipping the mattress: infinite polyurethane recycling by synthetic biology. Australia is covered in billions of tonnes of plastic and yet <10% is recycled today. Polyurethane (PU) is ubiquitous in our everyday lives, from lacquer coatings to elastane clothing to durable foam padding in car seats, cushions and mattresses. Currently, there are few avenues for PU recycling and much ends up in landfill e.g., a single mattress produces 15-20kg of PU foam waste. Luckily, biodegradation of PU can occu ....Flipping the mattress: infinite polyurethane recycling by synthetic biology. Australia is covered in billions of tonnes of plastic and yet <10% is recycled today. Polyurethane (PU) is ubiquitous in our everyday lives, from lacquer coatings to elastane clothing to durable foam padding in car seats, cushions and mattresses. Currently, there are few avenues for PU recycling and much ends up in landfill e.g., a single mattress produces 15-20kg of PU foam waste. Luckily, biodegradation of PU can occur naturally via various microbial means and from insects, like Galleria mellonella larvae. The overall aim of this research project is to understand plastic biodegradation and translate nature’s solutions into flexible and efficient synthetic enzyme technologies that can sustainably recycle commonly used PU foams. Read moreRead less
Special Research Initiatives - Grant ID: SR200200385
Funder
Australian Research Council
Funding Amount
$262,359.00
Summary
Transforming Democracy in the Bush: A Study of Politics in Rural Australia. This project aims to examine changing patterns of political participation and representation in rural Australia. Almost one third of our population lives outside major cities yet little is known about the democratic dynamics unfolding in rural Australia as it faces major demographic, economic and environmental change. Through in-depth case research this project will analyse how rural Australians participate in politics, ....Transforming Democracy in the Bush: A Study of Politics in Rural Australia. This project aims to examine changing patterns of political participation and representation in rural Australia. Almost one third of our population lives outside major cities yet little is known about the democratic dynamics unfolding in rural Australia as it faces major demographic, economic and environmental change. Through in-depth case research this project will analyse how rural Australians participate in politics, the interests they seek to advance and the efficacy of their political and civic activities. Expected outcomes include strengthened research capacity in rural politics, new frameworks for assessing how democracy is transforming, and reform pathways to enhance the engagement of diverse constituencies in our political system.Read moreRead less
Optimising plant populations for ecological restoration and resilience. When choosing individual plants for restoration populations, there is potentially a trade-off between maximising genetic diversity (‘adaptability’) and selection for desirable properties (‘adaptation’). This project aims to develop pioneering methods to quantify this trade-off, and facilitate the design of optimised populations, with a focus on two Australian rainforest trees that are being impacted by myrtle rust infection: ....Optimising plant populations for ecological restoration and resilience. When choosing individual plants for restoration populations, there is potentially a trade-off between maximising genetic diversity (‘adaptability’) and selection for desirable properties (‘adaptation’). This project aims to develop pioneering methods to quantify this trade-off, and facilitate the design of optimised populations, with a focus on two Australian rainforest trees that are being impacted by myrtle rust infection: Rhodamnia argentea and Rhodamnia rubescens. By studying the genetic variation in each species, and how this relates to myrtle rust resistance and climate, this project aims to design populations that are genetically diverse, maximally resistant to myrtle rust, and adapted to future climate.Read moreRead less
A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using ....A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using optically excited piezo-resistive sensors, and cold femtosecond laser ablation of hard dental tissue. Expected outcomes include a working prototype for laser removal of tooth materials at speeds exceeding dental drills, providing benefits in miniaturized laser devices and ultimately removing pain from dental procedures. Read moreRead less
Context and Activity Recognition for Personalised Behaviour Recommendation. The Internet of Things (IoT) together with the rising popularity of smartphones opens a new world for many exciting opportunities. The overall goal of this project is to develop new algorithms and data analytical techniques in an IoT environment that can accurately monitor and analyse personalised daily activities on a continuous, real-time basis. The expected result of this project will support many critical application ....Context and Activity Recognition for Personalised Behaviour Recommendation. The Internet of Things (IoT) together with the rising popularity of smartphones opens a new world for many exciting opportunities. The overall goal of this project is to develop new algorithms and data analytical techniques in an IoT environment that can accurately monitor and analyse personalised daily activities on a continuous, real-time basis. The expected result of this project will support many critical applications such as better wellness tracking and lifestyle-related illness prevention, which will be particularly critical to Australia's aging population. This project will also serve as a vehicle to educate and train Australia’s young scholars and engineers.Read moreRead less