The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH230100013
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Future Digital Manufacturing. This Hub aims to grow and accelerate Australian digital manufacturing (DM) transformation by devising novel DM technology and commercialisation/adoption pathways. The Hub expects to transform industry by developing novel AI and IoT-powered DM technology that provides for dramatic improvement in manufacturing productivity, resilience and competitiveness. Expected outcomes include novel DM technology for digitally representing, predicting, and imp ....ARC Research Hub for Future Digital Manufacturing. This Hub aims to grow and accelerate Australian digital manufacturing (DM) transformation by devising novel DM technology and commercialisation/adoption pathways. The Hub expects to transform industry by developing novel AI and IoT-powered DM technology that provides for dramatic improvement in manufacturing productivity, resilience and competitiveness. Expected outcomes include novel DM technology for digitally representing, predicting, and improving production and its outcomes via an open platform that supports reusing industry co-created DM solutions. Through supporting advanced manufacturing priorities and Industry 4.0, the Hub should provide significant benefits by increasing Australian manufacturing productivity and resilience by 30%.Read moreRead less
Stability Analysis of Power System with Massive Power Electronic Devices. The decarbonization of Australia's power systems is to integrate massive renewable energy sources which are interfaced with many power electronic devices (PEDs). The fast and complex dynamics of PEDs have significantly changed the nature of the power system, which limits the applicability of existing tools and methods to assess its stability. The goal of this project is to gain a comprehensive insight into the stability of ....Stability Analysis of Power System with Massive Power Electronic Devices. The decarbonization of Australia's power systems is to integrate massive renewable energy sources which are interfaced with many power electronic devices (PEDs). The fast and complex dynamics of PEDs have significantly changed the nature of the power system, which limits the applicability of existing tools and methods to assess its stability. The goal of this project is to gain a comprehensive insight into the stability of a futuristic power system with high penetration of PEDs. The intended outcomes will be a model and data jointly driven methodology for high-efficient and real-time stability assessment. The methodology developed in this project will support Australia's transition to a stable, secure, and low-carbon power grid.Read moreRead less
Transforming Microgrid to Virtual Power Plant –ICT Frameworks,Tools,Control. The project aims to enhance large scale renewable penetrations to national power grid by advancing control, optimization, and ancillary services of Virtual Power Plants (VPPs), considering different disruptive events including recent South Australian blackout. This project expects to create new control, frame communication architecture, develop plug and play type IoT enabled grid interfacing inverter, and optimize resou ....Transforming Microgrid to Virtual Power Plant –ICT Frameworks,Tools,Control. The project aims to enhance large scale renewable penetrations to national power grid by advancing control, optimization, and ancillary services of Virtual Power Plants (VPPs), considering different disruptive events including recent South Australian blackout. This project expects to create new control, frame communication architecture, develop plug and play type IoT enabled grid interfacing inverter, and optimize resource management for distributed VPPs. The anticipated benefits from this institutional level collaborations are that VPPs help in enhancing national power grid operations during normal and disruptive conditions when more renewables are connected and also secure benefits of consumers, prosumers, and grid operators.Read moreRead less
Exemplary early childhood educators at work: A multi-level investigation. Exemplary early childhood educators at work: A multi-level investigation. This project aims to inform strategies to better attract, prepare, recognise, support and retain a high quality workforce, by investigating the complexity of early childhood educators’ work. Seemingly entrenched workforce shortages threaten the objectives that governments and families seek through investment in early childhood education. Popular imag ....Exemplary early childhood educators at work: A multi-level investigation. Exemplary early childhood educators at work: A multi-level investigation. This project aims to inform strategies to better attract, prepare, recognise, support and retain a high quality workforce, by investigating the complexity of early childhood educators’ work. Seemingly entrenched workforce shortages threaten the objectives that governments and families seek through investment in early childhood education. Popular images of work with young children as easy and instinctual, or of teaching as only school based, mislead potential workforce entrants and erode the status of educators, leading to attrition. This project’s audit and description of exemplary educators’ work, across each level of mandated qualification, will inform strategies to sustain a high quality early childhood workforce into the future.Read moreRead less
Fisheries genomics of snapper in Australia and New Zealand Waters. This industry-driven project aims to assemble a strategic research alliance to generate and apply knowledge to a highly significant fisheries resource. It involves collaboration between the five major state government fisheries agencies in Australia, the New Zealand’s Crown Research Institute for seafood and two Australian labs with leadership in fish genetics and genomics. It expects to generate and integrate genomic, environmen ....Fisheries genomics of snapper in Australia and New Zealand Waters. This industry-driven project aims to assemble a strategic research alliance to generate and apply knowledge to a highly significant fisheries resource. It involves collaboration between the five major state government fisheries agencies in Australia, the New Zealand’s Crown Research Institute for seafood and two Australian labs with leadership in fish genetics and genomics. It expects to generate and integrate genomic, environmental and phenotypic datasets for snapper populations from across vast coastal regions of the two countries. The outcomes should substantially enhance intra- and inter-jurisdictional fisheries management and aquaculture initiatives, providing commercial, social and environmental benefits for many stakeholders.Read moreRead less
Designing the next generation of geosynthetic liner systems . The project aims to improve the effectiveness of geosynthetic liner systems to contain emerging contaminants such as per-and poly-fluoroalkyl substances (PFASs) for better protection of Australian groundwater resources. The project expects to experimentally validate theory to improve predictive models for performance of geosynthetic liner systems. Expected outcomes include new and updated design guidelines for effective environmental ....Designing the next generation of geosynthetic liner systems . The project aims to improve the effectiveness of geosynthetic liner systems to contain emerging contaminants such as per-and poly-fluoroalkyl substances (PFASs) for better protection of Australian groundwater resources. The project expects to experimentally validate theory to improve predictive models for performance of geosynthetic liner systems. Expected outcomes include new and updated design guidelines for effective environmental protection against PFASs and establishment of new approaches for predicting functional containment lifetimes of liner systems. These outcomes are expected to benefit the waste and remediation industries by influencing next-generation design regulations to ensure long-term environmental protection from PFAS.Read moreRead less