Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge ....Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge regarding the function of the CNS and deliver complex human cellular systems, that have both discovery and commercial applications.
Benefit: These platforms will have subsequent application revealing the mechanisms underlying numerous neurological diseases, with capacity to upscale for rapid drug screening.
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Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild ba ....Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild barley and identify appropriate candidate genes and their position on chromosomes for further incorporating these traits into commercial barley cultivars. This will reduce the environmental footprint of modern agricultural practices on terrestrial and aquatic ecosystems without compromising food security.Read moreRead less
The future of forests under climatic stress. This project aims to measure the vulnerability of forest trees to more extreme drought as global temperatures inevitably rise. Australian forests face the immediate threat of increased mortality associated with intensifying drought stress in the future. Understanding the magnitude of this threat is of the utmost urgency. This project aims to predict future mortality of forest communities in Australia and worldwide using recent breakthroughs enabling t ....The future of forests under climatic stress. This project aims to measure the vulnerability of forest trees to more extreme drought as global temperatures inevitably rise. Australian forests face the immediate threat of increased mortality associated with intensifying drought stress in the future. Understanding the magnitude of this threat is of the utmost urgency. This project aims to predict future mortality of forest communities in Australia and worldwide using recent breakthroughs enabling the rapid quantification of lethal stress in trees. This new understanding will provide a basis upon which to make far-reaching decisions about land management, conservation and restoration.Read moreRead less
How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their env ....How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their environment and the evolutionary history of the genes controlling this fundamental process. A major expected outcome is knowledge of the diversity of stomatal opening pathways, which should ultimately lead to improved predictions of plant responses to environmental change and assist future targeted modification of plant growth.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100014
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Sustainable Onshore Lobster Aquaculture. The project aims to build knowledge to establish the world’s first sustainable onshore lobster aquaculture industry focused on commercial, sustainable and socially responsible lobster production from hatchery to market. The project will investigate novel systems engineering, specialised feed manufacture, determination and modification of seedstock quality, new frontiers in seedstock transport, all within an informed environmental and ....ARC Research Hub for Sustainable Onshore Lobster Aquaculture. The project aims to build knowledge to establish the world’s first sustainable onshore lobster aquaculture industry focused on commercial, sustainable and socially responsible lobster production from hatchery to market. The project will investigate novel systems engineering, specialised feed manufacture, determination and modification of seedstock quality, new frontiers in seedstock transport, all within an informed environmental and marketing framework. The project will provide alternate solutions for lobster culture in bio-secure and cost effective onshore systems. The outcomes are targeted at positioning Australia at the forefront of onshore lobster aquaculture, with opportunity for technology transfer to other aquaculture sectors.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101133
Funder
Australian Research Council
Funding Amount
$427,067.00
Summary
The quick and the dead: identifying mechanisms for plant drought survival. This project aims to identify genes that control plant responses to low air humidity, which enhance drought survival by restricting water loss. Most plant water loss occurs through pores called stomata. This project expects to identify the genes that close stomata within minutes of decreased humidity by determining the molecular changes that occur over this timeframe and testing candidate genes for a critical role. Divers ....The quick and the dead: identifying mechanisms for plant drought survival. This project aims to identify genes that control plant responses to low air humidity, which enhance drought survival by restricting water loss. Most plant water loss occurs through pores called stomata. This project expects to identify the genes that close stomata within minutes of decreased humidity by determining the molecular changes that occur over this timeframe and testing candidate genes for a critical role. Diverse land plant models will be examined to ensure broad applicability of results. A major expected outcome is new knowledge of genes that minimise plant water loss, which would ultimately benefit plant-based industries through new targets for breeding improved, drought-adapted varieties for food security in a drying climate.Read moreRead less
Synthetic storage for improving flexibility and security of micro-grids. This project aims to remove the need for energy storage in micro-grids via adoption of synthetic storage. Micro-grids encounter high renewable energy penetrations early, given their small size. Typically, micro-grid variability is managed with technologies such as energy storage. Synthetic storage involves replacing fixed speed diesel assets with variable speed diesel technology. This project offers a cost-effective way to ....Synthetic storage for improving flexibility and security of micro-grids. This project aims to remove the need for energy storage in micro-grids via adoption of synthetic storage. Micro-grids encounter high renewable energy penetrations early, given their small size. Typically, micro-grid variability is managed with technologies such as energy storage. Synthetic storage involves replacing fixed speed diesel assets with variable speed diesel technology. This project offers a cost-effective way to improve renewable penetration and reduce diesel fuel consumption in micro-grids by removing the need for expensive energy storage. The expected project outcomes include reductions in cost and complexity for high renewable energy penetration micro-grids, reduced emissions and improved micro-grid reliability.Read moreRead less
Judges' work, place and psychological health - a national view. This project aims to address the human, juridical and financial costs of judicial officers’ work-related psychological harm. This harm is implicated in early retirement, sick leave and suicide. It threatens appropriate courtroom conduct, procedural fairness and impartial adjudication. The project seeks to generate new knowledge of the stress judicial officers experience and the individual and institutional mechanisms for managing st ....Judges' work, place and psychological health - a national view. This project aims to address the human, juridical and financial costs of judicial officers’ work-related psychological harm. This harm is implicated in early retirement, sick leave and suicide. It threatens appropriate courtroom conduct, procedural fairness and impartial adjudication. The project seeks to generate new knowledge of the stress judicial officers experience and the individual and institutional mechanisms for managing stressors, combining socio-legal and psychological approaches. Expected outcomes include evidence-based understandings to inform recruitment and retention strategies specific to this highly specialized workforce. This should provide significant benefits for judges’ work capacities and courts' delivery of justice.Read moreRead less