Exploring the immunomodulatory potential of Natural Killer T cells. Natural Killer T cells (NKT cells) are an innate-like population of T cells that recognise a range of lipid based antigens when bound to the antigen-presenting molecule, CD1d. Once activated, NKT cells rapidly secrete a variety of cytokines. This project, in partnership with Vaxine Pty Ltd, aims to gain a basic understanding of NKT recognition of lipids and NKT cell activation by lipids. The project aims to use a combination of ....Exploring the immunomodulatory potential of Natural Killer T cells. Natural Killer T cells (NKT cells) are an innate-like population of T cells that recognise a range of lipid based antigens when bound to the antigen-presenting molecule, CD1d. Once activated, NKT cells rapidly secrete a variety of cytokines. This project, in partnership with Vaxine Pty Ltd, aims to gain a basic understanding of NKT recognition of lipids and NKT cell activation by lipids. The project aims to use a combination of cellular immunology and structural biology to gain insight into NKT cell agonism.Read moreRead less
Photonic chip inertial movement sensors. This project aims to create a new class of optical inertial movement sensors using integrated photonic chip technology. By replacing optical fibre coils with compact waveguides, integrating light sources on-chip and by harnessing smart sensing approaches, we intend to reduce the required power from watts to milliwatts and reduce the dimensions from meters to centimetres. The expected project outcomes are sensors with military grade precision but with the ....Photonic chip inertial movement sensors. This project aims to create a new class of optical inertial movement sensors using integrated photonic chip technology. By replacing optical fibre coils with compact waveguides, integrating light sources on-chip and by harnessing smart sensing approaches, we intend to reduce the required power from watts to milliwatts and reduce the dimensions from meters to centimetres. The expected project outcomes are sensors with military grade precision but with the size, cost and manufacturability of consumer electronics. This technology will fill a strategic gap in the movement sensor market enabling applications ranging from robotic infrastructure monitoring, manufacture and surgery to guiding satellites and other space craft.Read moreRead less