Understanding and reversing the habitat shifts that have endangered the broad-headed snake. Extinction rates for vertebrate species are higher in southern Australia than almost anywhere else in the world, and saving endangered taxa is critical to biodiversity conservation. To do this effectively, researchers need to understand the processes that threaten wild populations, and to develop novel solutions to those problems in close collaboration with wildlife management authorities and other stake ....Understanding and reversing the habitat shifts that have endangered the broad-headed snake. Extinction rates for vertebrate species are higher in southern Australia than almost anywhere else in the world, and saving endangered taxa is critical to biodiversity conservation. To do this effectively, researchers need to understand the processes that threaten wild populations, and to develop novel solutions to those problems in close collaboration with wildlife management authorities and other stakeholders. This project will build such an understanding and collaboration, focusing on an endangered snake species. We propose ambitious landscape-scale field experiments that will simultaneously test hypotheses on threatening processes, and restore habitat quality to reverse population declines.Read moreRead less
Capture stress and post-capture survival of sharks and other chondrichthyans in fisheries bycatch. Australia is adopting ecosystem approaches to fisheries management. However, to embrace such an approach there is an urgent need for better information on the biology, ecology and population dynamics of sharks, rays and chimaeras (class Chondrichthyes). Chondrichthyan species are among the most sensitive in their response to the effects of fishing. Results from the present proposal will contribute ....Capture stress and post-capture survival of sharks and other chondrichthyans in fisheries bycatch. Australia is adopting ecosystem approaches to fisheries management. However, to embrace such an approach there is an urgent need for better information on the biology, ecology and population dynamics of sharks, rays and chimaeras (class Chondrichthyes). Chondrichthyan species are among the most sensitive in their response to the effects of fishing. Results from the present proposal will contribute to determining mortality of chondrichthyan bycatch species in response to the effects of capture in fishing gear, handling by fishers and discarding at sea. The work will contribute to biodiversity conservation and maintenance of ecosystem structure and function for present and future generations.Read moreRead less
Switching the light on cartilage repair. Osteoarthritis is a leading cause of pain and disability in adults and affects 15 per cent of the Australian population. This project will develop a revolutionary new approach to treat joint disorders using smart materials and stem cells. The novel materials and techniques developed will help Australia maintain its leading edge in biotechnology.
Development of new systems for the commercial collection, processing and storage of adipose stem cells. This project is aimed at developing a standardised method to commercially extract and expand stem cells from adipose tissue. This product will then be available commercially as a therapeutic treatment.
Dissecting the physiology of multipotent mesenchymal stromal cells to develop vaccine candidates for respiratory disease. The project aims to gain an understanding of how a type of adult stem cell inhibits immune responses that cause asthma. The project will produce new stem cell products and facilitate the design of a vaccine for asthma and other respiratory diseases, which would greatly reduce the burden of such conditions.
Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tib ....Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tibial defects. Furthermore, it will establish Australia's prominence in the tissue engineering field, training the next generation of young scientists and engineers. This technology will be of interest to numerous research groups and companies worldwide and will foster international collaboration, placing Australia at the forefront of this emerging field.Read moreRead less
Hazard identification, risk assessment and decision analysis for conservation and management of Australian marine parks. Victoria is the first jurisdiction in the world to proclaim an entire system of marine protected areas at once. The new management responsibilities have created imperatives for robust, scientifically defendable approaches to identifying threats, setting management priorities and developing monitoring systems. This project will develop, for the first time, a risk assessment pro ....Hazard identification, risk assessment and decision analysis for conservation and management of Australian marine parks. Victoria is the first jurisdiction in the world to proclaim an entire system of marine protected areas at once. The new management responsibilities have created imperatives for robust, scientifically defendable approaches to identifying threats, setting management priorities and developing monitoring systems. This project will develop, for the first time, a risk assessment protocol that has due regard for the perception of risks by individuals, and ensures that stakeholder values are an intrinsic part of decision-making. The protocol will create a system that stays faithful to the priorities of those who bear the risks, while using technical methods to ensure that models are consistent and that monitoring provides pertinent information.Read moreRead less