Integrated Exploration Of Novel Therapies For Depression
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
There is a clear need for new therapies for psychiatric illnesses, particularly depression. Current antidepressant therapy is useful but leaves many with a shortfall to functional recovery. My research program investigates new therapies for depression, in the context of the biological understanding of depression.
Nutraceuticals And Lifestyle Modification For Mood And Anxiety Disorders
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
Mood and anxiety disorders cause immense societal impact, and current treatment can be greatly improved. One particular way is via evidence-based use of nutrients and plant-based medicines, in addition to encouraging specific lifestyle changes (e.g. increased physical activity and improved diet). Dr Sarris' research focuses on these areas, aiming to build a robust body of evidence as to which of these interventions work (and which do not) to enhance better treatment of depression and anxiety.
Targeting Tumour-Stromal Interactions In Pancreatic Cancer
Funder
National Health and Medical Research Council
Funding Amount
$410,095.00
Summary
Pancreatic cancer claims five Australian lives every day and is one of the nations most lethal diseases. Despite aggressive treatment regimes, there has been no improvement in patient survival in the last decade. Evidence suggests that targeting cancer cells alone is not enough. The intense stromal reaction inhibits drug delivery and increases the aggressiveness of the tumours. Thus, depletion of the stroma or pancreatic stellate cells is a potential therapeutic target.