Degradable Nanocapsules For Thromboprophylaxis And Treatment Of Acute Thrombosis
Funder
National Health and Medical Research Council
Funding Amount
$1,158,447.00
Summary
The consequences of fat build up in vessels such as heart attacks and brain infarcts are the major cause of death in Australia. Clot busters have been proven to be beneficial for patients with heart attacks, clots in the legs or lungs and brain infarcts. However, the currently available drugs have major limitations in efficacy and in safety. The aim of this project is to develop novel drugs that have the potential to improve both significantly.
Antibody Targeted Thrombin-activatable ?-plasminogen Fusion Proteins And Nanocapsules For The Treatment Of Acute Thrombosis
Funder
National Health and Medical Research Council
Funding Amount
$536,951.00
Summary
The clinical consequences of atherosclerosis such as myocardial infarction and stroke are the major cause of mortality and morbidity in Australia. Clot dissolving agents have been proven to be beneficial in patients with acute myocardial infarction, vein thrombosis, pulmonary embolism, and stroke. However, the currently available drugs have major limitations in efficacy and in safety. The aim of this project is to develop novel drugs that have the potential to improve both significantly.