Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
Towards an effective practice model for youth detention. This project aims to examine the effectiveness of an innovative government program, which seeks to enhance the safety and rehabilitative culture of juvenile detention centres by increasing staff interpersonal skills through specialist training, coaching and supervision. The project is expected to identify best practice principles, allowing government departments to focus efforts on training and staff support to provide a higher quality wor ....Towards an effective practice model for youth detention. This project aims to examine the effectiveness of an innovative government program, which seeks to enhance the safety and rehabilitative culture of juvenile detention centres by increasing staff interpersonal skills through specialist training, coaching and supervision. The project is expected to identify best practice principles, allowing government departments to focus efforts on training and staff support to provide a higher quality work force. An evidence based framework will be developed in consultation with juvenile justice agencies across Australia. This will potentially improve outcomes for young people in custody and the wider community.Read moreRead less
The Intended and Unintended Impact of Policy for Adaptive Policy Management. The project aims to advance knowledge about the intended and unintended consequences of policy on health and well-being. It expects to innovate through new methods and novel data to integrate policy evaluation into the policy cycle in a timely fashion to prevent harm from occurring. It also leverages technology to track policy effects in real time. Expected outcomes of this project include new knowledge and enhanced pol ....The Intended and Unintended Impact of Policy for Adaptive Policy Management. The project aims to advance knowledge about the intended and unintended consequences of policy on health and well-being. It expects to innovate through new methods and novel data to integrate policy evaluation into the policy cycle in a timely fashion to prevent harm from occurring. It also leverages technology to track policy effects in real time. Expected outcomes of this project include new knowledge and enhanced policy infrastructure using new methods and interdisciplinary approaches. Significant benefits include improvements to: (1) policy management by government departments; (2) the health and wellbeing of the Australians they serve; (3) our Partners' capacity to consult governments on how technology can assist policy management. Read moreRead less
A Cluster RCT Of A Novel Psychological Intervention To Reduce Depression Among At-risk Older Adults Transitioning To Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$893,152.00
Summary
Depression is common in aged care facilities, with many older adults finding the transition extremely difficult. We have developed a simple intervention to help new residents, including those with dementia, to adjust to life in aged care. This program focuses on key aspects of psychological wellbeing, and is designed for widespread use in aged care. We will evaluate the intervention to determine if it is superior to current care approaches in reducing depression and improving quality of life.
Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water ....Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water and soil should lead to deeper understanding of the dynamics, variation and transfer of genetic material within these resources’ microbial communities, strategies to manage microbial diversity, and improved productivity and long-term sustainability for these resources.Read moreRead less
Driving Change: Using Emergency Department Data To Reduce Alcohol-related Harm
Funder
National Health and Medical Research Council
Funding Amount
$1,468,026.00
Summary
The proposed project is a system change within partner emergency departments, providing them the information and tools to act on both risky alcohol consumption in individual patients and the sources of alcohol in the community which cause the harm they experience. Most importantly, the proposed public health interventions act as a tool for emergency departments to regularly raise awareness with the public and policymakers regarding the impact of alcohol on patients, clinicians and hospitals.
Intercultural understanding in primary and secondary schools. What facilitates or impedes intercultural understanding in children, adolescents and schools? How can this be addressed? How can we know what makes a difference? This project answers these questions at the individual, school and national level using a novel cultural systems approach and methodological and technological innovations.
Networks in Flux: Examining how sector relationships adapt to rapid change. This study aims to investigate why, when and how inter-organisational networks adapt or remain resistant to change. Responding to complex social problems and technological change requires inter-organisational networks to be adaptable. Through a combination of longitudinal network analysis, survey research and qualitative interviews, this project plans to study the Victorian HIV and hepatitis C sector as it responds to ma ....Networks in Flux: Examining how sector relationships adapt to rapid change. This study aims to investigate why, when and how inter-organisational networks adapt or remain resistant to change. Responding to complex social problems and technological change requires inter-organisational networks to be adaptable. Through a combination of longitudinal network analysis, survey research and qualitative interviews, this project plans to study the Victorian HIV and hepatitis C sector as it responds to major advances in prevention and treatment, requiring community, health, policy and research organisations to adapt their roles and relationships. This timely and novel study aims to improve our knowledge of how to enable inter-organisational networks to adapt and improve organisational responsiveness to complex issues.Read moreRead less
Building the numeracy and information and communication technology capability of students with intellectual disabilities. This project investigates strategies to build numeracy and information and communication technology capability among students with intellectual disabilities. It aims to support teachers in mainstream and special education schools as they plan and monitor personalised instruction for their students. The research combines disciplines of special schools, the state Education Depa ....Building the numeracy and information and communication technology capability of students with intellectual disabilities. This project investigates strategies to build numeracy and information and communication technology capability among students with intellectual disabilities. It aims to support teachers in mainstream and special education schools as they plan and monitor personalised instruction for their students. The research combines disciplines of special schools, the state Education Department’s Student Inclusion and Wellbeing Division, and the Assessment Research Centre. The expected outcome is an integrated program of assessment, reporting, curriculum, and instructional advice that promotes inclusive educational practices and seeks to ensure all children have improved opportunities to participate in a technology driven, emerging knowledge economy.Read moreRead less
Workplace Interventions To Reduce The Cost Of Neck Problems In Office Personnel
Funder
National Health and Medical Research Council
Funding Amount
$660,834.00
Summary
Neck pain in office workers is a major burden in industry in terms of lost productivity and personal suffering. This research will evaluate a novel intervention for the prevention and management of neck pain in computer users. The impact and value of neck specific exercises and best practice office ergonomics will be evaluated from the employers (productivity loss) and workers perspective (severity of neck pain). The findings will directly benefit future management of this significant health iss ....Neck pain in office workers is a major burden in industry in terms of lost productivity and personal suffering. This research will evaluate a novel intervention for the prevention and management of neck pain in computer users. The impact and value of neck specific exercises and best practice office ergonomics will be evaluated from the employers (productivity loss) and workers perspective (severity of neck pain). The findings will directly benefit future management of this significant health issue.Read moreRead less