Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
A Cluster RCT Of A Novel Psychological Intervention To Reduce Depression Among At-risk Older Adults Transitioning To Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$893,152.00
Summary
Depression is common in aged care facilities, with many older adults finding the transition extremely difficult. We have developed a simple intervention to help new residents, including those with dementia, to adjust to life in aged care. This program focuses on key aspects of psychological wellbeing, and is designed for widespread use in aged care. We will evaluate the intervention to determine if it is superior to current care approaches in reducing depression and improving quality of life.
Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water ....Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water and soil should lead to deeper understanding of the dynamics, variation and transfer of genetic material within these resources’ microbial communities, strategies to manage microbial diversity, and improved productivity and long-term sustainability for these resources.Read moreRead less
Driving Change: Using Emergency Department Data To Reduce Alcohol-related Harm
Funder
National Health and Medical Research Council
Funding Amount
$1,468,026.00
Summary
The proposed project is a system change within partner emergency departments, providing them the information and tools to act on both risky alcohol consumption in individual patients and the sources of alcohol in the community which cause the harm they experience. Most importantly, the proposed public health interventions act as a tool for emergency departments to regularly raise awareness with the public and policymakers regarding the impact of alcohol on patients, clinicians and hospitals.
Intercultural understanding in primary and secondary schools. What facilitates or impedes intercultural understanding in children, adolescents and schools? How can this be addressed? How can we know what makes a difference? This project answers these questions at the individual, school and national level using a novel cultural systems approach and methodological and technological innovations.
Building the numeracy and information and communication technology capability of students with intellectual disabilities. This project investigates strategies to build numeracy and information and communication technology capability among students with intellectual disabilities. It aims to support teachers in mainstream and special education schools as they plan and monitor personalised instruction for their students. The research combines disciplines of special schools, the state Education Depa ....Building the numeracy and information and communication technology capability of students with intellectual disabilities. This project investigates strategies to build numeracy and information and communication technology capability among students with intellectual disabilities. It aims to support teachers in mainstream and special education schools as they plan and monitor personalised instruction for their students. The research combines disciplines of special schools, the state Education Department’s Student Inclusion and Wellbeing Division, and the Assessment Research Centre. The expected outcome is an integrated program of assessment, reporting, curriculum, and instructional advice that promotes inclusive educational practices and seeks to ensure all children have improved opportunities to participate in a technology driven, emerging knowledge economy.Read moreRead less
Workplace Interventions To Reduce The Cost Of Neck Problems In Office Personnel
Funder
National Health and Medical Research Council
Funding Amount
$660,834.00
Summary
Neck pain in office workers is a major burden in industry in terms of lost productivity and personal suffering. This research will evaluate a novel intervention for the prevention and management of neck pain in computer users. The impact and value of neck specific exercises and best practice office ergonomics will be evaluated from the employers (productivity loss) and workers perspective (severity of neck pain). The findings will directly benefit future management of this significant health iss ....Neck pain in office workers is a major burden in industry in terms of lost productivity and personal suffering. This research will evaluate a novel intervention for the prevention and management of neck pain in computer users. The impact and value of neck specific exercises and best practice office ergonomics will be evaluated from the employers (productivity loss) and workers perspective (severity of neck pain). The findings will directly benefit future management of this significant health issue.Read moreRead less
Evaluation in health promotion: gathering evidence to improve effectiveness. Effective disease prevention and health promotion to address the public health challenges facing Australia requires a strong evidence base for policy and practice. Evaluation of programs in natural contexts is a vital source of this evidence, valuable for improving strategy design and delivery, building sustainability and guiding funding. The aim of this project is to determine the strengths and limitations of evaluatio ....Evaluation in health promotion: gathering evidence to improve effectiveness. Effective disease prevention and health promotion to address the public health challenges facing Australia requires a strong evidence base for policy and practice. Evaluation of programs in natural contexts is a vital source of this evidence, valuable for improving strategy design and delivery, building sustainability and guiding funding. The aim of this project is to determine the strengths and limitations of evaluation by health promotion agencies, and to identify the roles of individual, organisational and system-level factors in relation to evaluation practice and use. This knowledge is expected to guide efforts to build capacity for evaluation, improve systems for organisational learning, and enable evidence gathering to improve effectiveness.Read moreRead less
Profiling developmental standards of learning for students with intellectual disabilities. This project addresses an area of educational assessment that has been traditionally neglected as 'too hard'. It offers hope to students with intellectual disabilities. If developmental progress can be mapped and identified in competency terms and linked to successful teaching and learning strategies, the students can be expected to make more rapid progress towards achieving their potential. Teachers in ma ....Profiling developmental standards of learning for students with intellectual disabilities. This project addresses an area of educational assessment that has been traditionally neglected as 'too hard'. It offers hope to students with intellectual disabilities. If developmental progress can be mapped and identified in competency terms and linked to successful teaching and learning strategies, the students can be expected to make more rapid progress towards achieving their potential. Teachers in mainstream schools can also expect to be helped in recognising development and given advice for intervention. The materials will be made available world wide to help all students in this challenging area.Read moreRead less
Realising the Potential of Australia’s High Capacity Students. This project aims to investigate factors that contribute to high capacity students failing to improve in literacy, numeracy and problem solving compared with their lower capacity peers. The project aims to focus on protective factors that might mitigate against this negative association between capacity and achievement. The study and method extends previous research the influence of evidence-based decisions by collaborative teacher t ....Realising the Potential of Australia’s High Capacity Students. This project aims to investigate factors that contribute to high capacity students failing to improve in literacy, numeracy and problem solving compared with their lower capacity peers. The project aims to focus on protective factors that might mitigate against this negative association between capacity and achievement. The study and method extends previous research the influence of evidence-based decisions by collaborative teacher teams on student achievement. In partnership with the Victorian Department of Education and Early Childhood Development, this project seeks to identify ways that will enable systems of education to realise the learning potential of all students.Read moreRead less