Tailoring composite propellers for reduced sound radiation. This project aims to explore the generation of noise by composite propellers and to use this understanding to tailor the composite properties to reduce underwater noise. Propellers are a harmful source of noise in the marine environment, disturbing animal behaviour, revealing the location of naval vessels and interfering with sonar operation. Adaptive composite propellers are potentially quieter than metal propellers, as well as offerin ....Tailoring composite propellers for reduced sound radiation. This project aims to explore the generation of noise by composite propellers and to use this understanding to tailor the composite properties to reduce underwater noise. Propellers are a harmful source of noise in the marine environment, disturbing animal behaviour, revealing the location of naval vessels and interfering with sonar operation. Adaptive composite propellers are potentially quieter than metal propellers, as well as offering improvements in efficiency and fuel consumption. The aims of this project are to understand the physical mechanisms associated with composite propeller noise generation. The outcomes are intended to provide advanced numerical capabilities that will support the development of quieter marine propeller designs to improve defence capability and the acoustic environment for marine mammals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100082
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
An Australasian facility for the automated fabrication of high performance bespoke components. A facility for the automated fabrication of high performance bespoke components: The project will create a new coordinated facility for composites research including modern automated infrastructure. The facility will bring Australia in line with leading international research centres and promote fundamental and applied research into a range of fields including underwater renewable energy systems, space ....An Australasian facility for the automated fabrication of high performance bespoke components. A facility for the automated fabrication of high performance bespoke components: The project will create a new coordinated facility for composites research including modern automated infrastructure. The facility will bring Australia in line with leading international research centres and promote fundamental and applied research into a range of fields including underwater renewable energy systems, space vehicle structures, multifunctional and smart materials and infrastructure capacity extension. The facility will position Australian research for significant international collaboration through endorsement of next-generation manufacturing technology and enable leading outcomes for Australasian science and engineering in aerospace, marine, civil, automotive, renewable energy and primary resources.Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge mic ....Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge microscopy techniques to visualise whether the endogenous astrocyte protein metallothionein can promote regeneration in the injured nervous system of living zebrafish. The successful outcomes of this project will provide significant insight into understanding how the brain responds to injury.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.