Cellular genomic approach to the pathogenesis of multiple sclerosis. This project compares the levels of gene usage in two important immune cell types between patients with multiple sclerosis and people who do not have the disease. It aims to identify the molecular basis for the disease, in order to identify new diagnostic, preventative and treatment options.
Efficacy Of Education And Advice Delivered By Text Message To Aid Smoking Cessation
Funder
National Health and Medical Research Council
Funding Amount
$538,395.00
Summary
A high proportion of smokers indicate a desire to stop smoking and report having made attempts to quit. However, most attempts are not successful and new methods are needed to support motivated smokers and improve success rates. This project evaluates the use of text messages to deliver advice and support to smokers motivated to stop smoking. We aim to understand if and how this promosing new intervention helps smokers to quit.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
Ultrasound in muscle vascular research, and gene therapy. This project focuses on ultrasound and microbubbles for the imaging of microvascular blood flow patterns in skeletal muscle and as a modality for drug delivery. The aim is to develop and refine technology specifically for (i) assessment of muscle microvascular flow in health and disease, and for (ii) delivery of state-of-the art gene constructs to endothelial cells that control blood flow in the muscle microvasculature. We anticipate impr ....Ultrasound in muscle vascular research, and gene therapy. This project focuses on ultrasound and microbubbles for the imaging of microvascular blood flow patterns in skeletal muscle and as a modality for drug delivery. The aim is to develop and refine technology specifically for (i) assessment of muscle microvascular flow in health and disease, and for (ii) delivery of state-of-the art gene constructs to endothelial cells that control blood flow in the muscle microvasculature. We anticipate improved technology for early diagnosis of impairment in microvascular flow relevant to muscle insulin resistance and novel therapeutics that improve muscle microvascular blood flow applicable to the treatment of diabetes.Read moreRead less
Inherited determinants of cancer aetiology. Family history of cancer is a strong risk factor for many cancers. This project will aim to identify inherited factors influencing risk of developing cancer and those factors influencing the course of the disease and outcomes.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0452281
Funder
Australian Research Council
Funding Amount
$102,900.00
Summary
Muscle Vascular Research and Gene Therapy Using Ultrasound. We seek funds to set up a national facility for ultrasound in muscle vascular research and gene therapy. Ultrasound with microbubbles will be used for the imaging of muscle microvascular blood flow and as a delivery modality for gene constructs to endothelial cells that control blood flow. The technology has application to (i) the assessment and therapeutic treatment of impaired microvascular function as in diabetics; (ii) the assessmen ....Muscle Vascular Research and Gene Therapy Using Ultrasound. We seek funds to set up a national facility for ultrasound in muscle vascular research and gene therapy. Ultrasound with microbubbles will be used for the imaging of muscle microvascular blood flow and as a delivery modality for gene constructs to endothelial cells that control blood flow. The technology has application to (i) the assessment and therapeutic treatment of impaired microvascular function as in diabetics; (ii) the assessment of adaptation to physical training and (iii) the development of therapeutic agents used to treat diabetes. We anticipate improved technology that is fully characterized and novel therapeutics that improve microvascular blood flow.Read moreRead less
Genealogy and Topology: A Constellational Comparison of Nietzsche and Heidegger. This research is fundamental in character addressing basic questions about the nature and history of philosophy. It will have direct academic benefits in advancing disciplinary knowledge, in enhancing the reputation of Australian philosophy in Germany and internationally, and in promoting contact between Australian and German philosophers, but is also likely to have longer term benefits in furthering our understandi ....Genealogy and Topology: A Constellational Comparison of Nietzsche and Heidegger. This research is fundamental in character addressing basic questions about the nature and history of philosophy. It will have direct academic benefits in advancing disciplinary knowledge, in enhancing the reputation of Australian philosophy in Germany and internationally, and in promoting contact between Australian and German philosophers, but is also likely to have longer term benefits in furthering our understanding of the nature of concepts, and of conceptual creativity.Read moreRead less
The global vaccination revolution: a transnational and comparative perspective. A study of first global immunization campaign will provide a historical dimension to contemporary concerns about pandemic disease, vaccination and bio-terrorism, and generate new insights into the factors determining the success and failure of public health initiatives. The project relates directly to national research priorities in health and safeguarding Australia. It has more specific relevance to Australia. Small ....The global vaccination revolution: a transnational and comparative perspective. A study of first global immunization campaign will provide a historical dimension to contemporary concerns about pandemic disease, vaccination and bio-terrorism, and generate new insights into the factors determining the success and failure of public health initiatives. The project relates directly to national research priorities in health and safeguarding Australia. It has more specific relevance to Australia. Smallpox decimated the Aboriginal population, and quarantine and vaccination have loomed large in Australian history. It builds on Australia's strong scholarship in the fields of virology and immunology and the history of disease and public health.Read moreRead less
The World Arm-to-Arm: The Spread of Smallpox Vaccination and Global Networks of Knowledge and Power, 1799-1805. This project will document the rapid spread of Jenner's vaccine around the world between 1799 and 1805. It will address matters neglected in the existing literature, including the logistics of the global transmission of the vaccine, often literally arm-to-arm; the promotion and reception of vaccination in different social and cultural contexts; and the networks of power and knowledge ....The World Arm-to-Arm: The Spread of Smallpox Vaccination and Global Networks of Knowledge and Power, 1799-1805. This project will document the rapid spread of Jenner's vaccine around the world between 1799 and 1805. It will address matters neglected in the existing literature, including the logistics of the global transmission of the vaccine, often literally arm-to-arm; the promotion and reception of vaccination in different social and cultural contexts; and the networks of power and knowledge that made the Jennerian revolution possible. The project will result in a book and articles, interventions in the literature on globalisation and the adoption of innovation, and a deeper and broader perspective on issues of burning relevance to the world today.Read moreRead less