Australian Laureate Fellowships - Grant ID: FL120100030
Funder
Australian Research Council
Funding Amount
$2,779,572.00
Summary
Engineering materials for advances in nanomedicine. Nanomedicine is one of the fastest growing areas in nanotechnology. This project will develop next-generation particle systems with engineered properties that are expected to underpin advances in the delivery of therapeutics in the areas of cancer, vaccines, cardiovascular disease and neural health.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100160
Funder
Australian Research Council
Funding Amount
$297,463.00
Summary
Femtosecond laser micropyrolysis gas chromatograph-mass spectrometer. This project aims to build a femtosecond-laser, micropyrolysis gas-chromatographmass spectrometer. The facility will have the capability to selectively analyse very small petrographically-recognisable organic components, hence bridging the analytical gap between organic petrography and organic geochemistry. The project aims to understand the early evolution of life, the response of the biosphere to mass extinction, the migrati ....Femtosecond laser micropyrolysis gas chromatograph-mass spectrometer. This project aims to build a femtosecond-laser, micropyrolysis gas-chromatographmass spectrometer. The facility will have the capability to selectively analyse very small petrographically-recognisable organic components, hence bridging the analytical gap between organic petrography and organic geochemistry. The project aims to understand the early evolution of life, the response of the biosphere to mass extinction, the migration of fluids in petroleum reservoirs, the heterogeneity of organic matter in shale gas reservoirs, and the composition of macromolecules in biominerals and macerals. The facility will contribute to a broad range of Australia’s theoretical and applied problems in geoscience and geobiology.Read moreRead less
Nanoengineered Polymeric Materials for Environmental and Biological Applications. The development of advanced materials with nanoengineered properties promises to revolutionise future industries, including the energy and healthcare sectors. This research program will involve the design, synthesis and assembly of tailored polymers to prepare next-generation, engineered materials. The research will deliver advanced polymeric membranes, tissue engineering scaffolds and vaccine delivery systems. The ....Nanoengineered Polymeric Materials for Environmental and Biological Applications. The development of advanced materials with nanoengineered properties promises to revolutionise future industries, including the energy and healthcare sectors. This research program will involve the design, synthesis and assembly of tailored polymers to prepare next-generation, engineered materials. The research will deliver advanced polymeric membranes, tissue engineering scaffolds and vaccine delivery systems. These materials are expected to provide benefits for Australian citizens in the energy and health sectors and contribute to the development of a robust Australian nanotechnology industry. The projects will also provide opportunities for the development of outstanding young scientists and will foster multidisciplinary collaborations.Read moreRead less
The evolution of cooperative communication. This interdisciplinary project will provide a broad understanding of communication in a model ecological system involving ants, lycaenid butterflies, and host-plants. The project will reveal the nature of the chemical signals used to communicate, and their role in the origin, maintenance, and loss of mutualistic and parasitic associations.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100127
Funder
Australian Research Council
Funding Amount
$355,000.00
Summary
Superresolution fluorescence imaging in microbiology. Superresolution fluorescence imaging in microbiology:
This project involves the purchase of new, and upgrade of existing, fluorescence imaging tools to facilitate the study of intracellular processes in microbial systems at significantly higher spatial and temporal resolutions than hitherto possible. Visualisation of the structure and dynamics of intracellular molecular assemblies at maximal resolution is required to understand protein funct ....Superresolution fluorescence imaging in microbiology. Superresolution fluorescence imaging in microbiology:
This project involves the purchase of new, and upgrade of existing, fluorescence imaging tools to facilitate the study of intracellular processes in microbial systems at significantly higher spatial and temporal resolutions than hitherto possible. Visualisation of the structure and dynamics of intracellular molecular assemblies at maximal resolution is required to understand protein function inside living cells. The new equipment is designed to provide a fast super-resolution imaging system to study the intracellular dynamics of proteins in vitro and a super-resolution microscope to visualise structures and assemblies inside microbes with a resolution of tens of nanometres, putting in vitro biochemistry into the context of a living cell. Read moreRead less
Effect of a novel immobilised antimicrobial peptide on bacteria. This project plans to investigate a novel cationic peptide that prevents microbial colonisation of surfaces. The ability of bacteria to colonise surfaces affects almost all aspects of human life – from water to food and medical devices. As microbes become increasingly resistant to traditional biocides, the design of effective antimicrobial surfaces to prevent microbial colonisation and biofilm formation is critically important. The ....Effect of a novel immobilised antimicrobial peptide on bacteria. This project plans to investigate a novel cationic peptide that prevents microbial colonisation of surfaces. The ability of bacteria to colonise surfaces affects almost all aspects of human life – from water to food and medical devices. As microbes become increasingly resistant to traditional biocides, the design of effective antimicrobial surfaces to prevent microbial colonisation and biofilm formation is critically important. The novel cationic peptide may provide a solution, but the mechanism of action of surface-bound peptides on bacteria is poorly understood. This project aims to combine biophysics, biochemistry, microbiology and molecular biology to study interactions with the surface of two model bacteria. This may facilitate optimal design of new coatings.Read moreRead less
A multimodal approach to unravel the role of surface properties in nanoparticle-cell interactions using models of medical emergencies. The design and development of multimodal nanoparticles seek to expand upon the benefits of nanoparticles by delivering imaging and therapeutic agents to specific organs, enabling detection and treatment of disease in a single procedure. The successful implementation of this technology is dependent on our detailed understanding of the nanoparticle-cell interaction ....A multimodal approach to unravel the role of surface properties in nanoparticle-cell interactions using models of medical emergencies. The design and development of multimodal nanoparticles seek to expand upon the benefits of nanoparticles by delivering imaging and therapeutic agents to specific organs, enabling detection and treatment of disease in a single procedure. The successful implementation of this technology is dependent on our detailed understanding of the nanoparticle-cell interactions. This project will address this very important issue by evaluating a range of surface functionalised nanoparticles in highly significant models of medical emergencies. This project will enable development of advanced therapeutic interventions for cancer, central nervous system injuries, cardiovascular diseases and pregnancy related disorders.Read moreRead less
Optimisation of functional mesoporous materials for low-abundance biomarkers quantification towards biodiagnostic applications. Using state-of-the-art nanotechnology, a novel approach will be developed to quantitatively analyse low abundance peptides and proteins. This will aid in the detection of a biomarker in osteoarthritis, a disease affecting 3.85 million Australians. This project has significance for the early diagnosis and improved treatment of this disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100131
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Biomaterials characterisation facility. The convergence of nanotechnology and biotechnology offers new opportunities to prepare nanoengineered materials for applications in biomedicine. The Biomaterials Characterisation Facility will provide equipment to characterise such nanoengineered materials to underpin advances in therapeutic drug delivery and tissue engineering.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100040
Funder
Australian Research Council
Funding Amount
$1,375,000.00
Summary
An advanced electron microscope facility for nanomaterials, functional materials and minerals. An advanced electron microscope facility for nanomaterials, functional materials and minerals: Recent advances in electron microscopy provide instruments that can resolve at the atomic level and image both morphologically and chemically at these resolutions. These modern instruments are also less complex to operate therefore allowing many more researchers to access them directly. The High Resolution Sc ....An advanced electron microscope facility for nanomaterials, functional materials and minerals. An advanced electron microscope facility for nanomaterials, functional materials and minerals: Recent advances in electron microscopy provide instruments that can resolve at the atomic level and image both morphologically and chemically at these resolutions. These modern instruments are also less complex to operate therefore allowing many more researchers to access them directly. The High Resolution Scanning Transmission Electron Microscope will allow a complete, nano-scale characterisation of natural and synthetic materials in a broad range of scientific, engineering and industrial applications. The Field Emission Scanning Electron Microscope will provide nano-science users with a tool that can image many of the processes in the formation of these nanostructures and particles.Read moreRead less