Optical tweezers as a micro-rheological probe of soft surfaces. Biomembranes are more than soft containers - their dynamic flexibility plays an important role in cell function, but measurements of mechanical properties of soft surfaces are non-existent. This project develops and applies a new optical tweezers method to measure the flexibility of membranes and its effects upon the friction of nearby particles.
Discovery Early Career Researcher Award - Grant ID: DE190100803
Funder
Australian Research Council
Funding Amount
$418,956.00
Summary
Single-enzyme membrane biofuel cells for wastewater and flue gas treatment. This project aims to mitigate energy and environmental problems by fusing the fields of membrane separation, biocatalysis and electrochemistry. The novel single-enzyme biofuel cells can generate electrical power from processes like wastewater micropollutant degradation and flue gas carbon dioxide conversion. However, the bottleneck is the lifetime of enzymes and the lack of efficient reactor design. This project expects ....Single-enzyme membrane biofuel cells for wastewater and flue gas treatment. This project aims to mitigate energy and environmental problems by fusing the fields of membrane separation, biocatalysis and electrochemistry. The novel single-enzyme biofuel cells can generate electrical power from processes like wastewater micropollutant degradation and flue gas carbon dioxide conversion. However, the bottleneck is the lifetime of enzymes and the lack of efficient reactor design. This project expects to overcome these challenges by developing metal-organic framework-based bioelectrode materials, and integrating them with separation membranes and single-enzyme fuel cells for energy generation. This project is expected to transform the current biocatalytic process for wastewater treatment and gas separation.Read moreRead less
Linking topology and rheology for designing supramolecular polymer networks. This project aims to develop a foundation for understanding how microscopic topology and intermolecular interactions control the flow behaviour of supramolecular polymer networks. Brownian dynamics algorithms will be developed to unravel the complex dynamics of the network and calibrated by comparison with carefully designed experiments. The expected outcome of the project is a quantitative framework for connecting the ....Linking topology and rheology for designing supramolecular polymer networks. This project aims to develop a foundation for understanding how microscopic topology and intermolecular interactions control the flow behaviour of supramolecular polymer networks. Brownian dynamics algorithms will be developed to unravel the complex dynamics of the network and calibrated by comparison with carefully designed experiments. The expected outcome of the project is a quantitative framework for connecting the molecular structure and energy landscape with resulting macroscopic properties. This project should yield significant benefit in the rational design of supramolecular systems in which the thermorheological properties can be tuned over a wide range of force/time scales with applications spanning from enhanced oil recovery to injectable hydrogels.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100082
Funder
Australian Research Council
Funding Amount
$408,000.00
Summary
Nanostructures derived from metal-organic frameworks for sodium-ion batteries. This project aims to overcome poor reaction kinetics and the lack of effective anode materials owing to the large size of sodium-ions in high performance sodium-ion batteries. The project will explore a series of functional nanomaterials with unique nanostructures and complex compositions, enabled by metal-organic framework assisted synthetic methods. High performance sodium ion batteries are demonstrating great poten ....Nanostructures derived from metal-organic frameworks for sodium-ion batteries. This project aims to overcome poor reaction kinetics and the lack of effective anode materials owing to the large size of sodium-ions in high performance sodium-ion batteries. The project will explore a series of functional nanomaterials with unique nanostructures and complex compositions, enabled by metal-organic framework assisted synthetic methods. High performance sodium ion batteries are demonstrating great potential to meet the future demand for large-scale and low-cost stationary energy storage. However, their practical implementation is still hindered by their poor reaction kinetics and the lack of effective anode materials owing to the large size of sodium-ions. The project outcomes will promote the commercialisation of sodium ion batteries and power Australia’s sustainable economy in the long run.Read moreRead less
Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour ....Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour requirement, higher production rate and better quality control than conventional production methods. The new process will combine benefits from both supercritical fluid technology (green process) and microfluidics (high mass & heat transfer).Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101043
Funder
Australian Research Council
Funding Amount
$413,482.00
Summary
Peculiar membrane structures for removing microplastics from water. Microplastic pollution can inflict irreparable damage to human health and the environment. This project aims to develop functional membrane structures specifically designed to remove microplastics from aquatic and wastewater treatment systems. The approach will utilise advanced techniques in material science, separation science and fluid mechanics. The expected outcomes include advanced membranes with high separation efficiency ....Peculiar membrane structures for removing microplastics from water. Microplastic pollution can inflict irreparable damage to human health and the environment. This project aims to develop functional membrane structures specifically designed to remove microplastics from aquatic and wastewater treatment systems. The approach will utilise advanced techniques in material science, separation science and fluid mechanics. The expected outcomes include advanced membranes with high separation efficiency for microplastics filtration. This will have significant benefits, including the efficient removal of microplastics from water sources securing cleaner potable, irrigation and recycled water, and contributing to a safer, healthier environment for all Australians.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100208
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
An advanced computational facility based on a graphic processing unit for particulate research. The graphic processing unit (GPU) is becoming an engine for the next generation of supercomputers for scientific research. The technology at this new facility will be exploited to perform large-scale, real time simulations of complex particulate material processing which is critical to Australia’s mineral/metallurgical/material industries.
Rare Earth Metal Separation by Polymer Inclusion Membranes. The project aims to develop a novel hydrometallurgical method for the separation of the rare earth metals dysprosium and terbium from mixed rare earth metal solutions using polymer inclusion membranes with a crosslinked or non-crosslinked polymer backbone. These metals are crucial for the manufacturing of advanced technology products. The membrane-based method is expected to offer significant advantages over the currently used solvent e ....Rare Earth Metal Separation by Polymer Inclusion Membranes. The project aims to develop a novel hydrometallurgical method for the separation of the rare earth metals dysprosium and terbium from mixed rare earth metal solutions using polymer inclusion membranes with a crosslinked or non-crosslinked polymer backbone. These metals are crucial for the manufacturing of advanced technology products. The membrane-based method is expected to offer significant advantages over the currently used solvent extraction methods by eliminating the use of solvents and conducting the separation as a continuous process where the extraction and back-extraction steps take place simultaneously. These advantages are expected to make the separation process more cost-effective and drastically reduce its environmental impact.Read moreRead less
Unravelling the mechanics of particle deposition at the micro-scale. This project aims to discover the mechanisms responsible for the interactions between aerosol particles and surfaces in a range of air flow conditions. The project expects to transform our understanding of particle deposition through a combination of novel laser-based diagnostic techniques, optical coherence tomography, and state of the art particle formulation methodologies. Expected outcomes of the project include delivery of ....Unravelling the mechanics of particle deposition at the micro-scale. This project aims to discover the mechanisms responsible for the interactions between aerosol particles and surfaces in a range of air flow conditions. The project expects to transform our understanding of particle deposition through a combination of novel laser-based diagnostic techniques, optical coherence tomography, and state of the art particle formulation methodologies. Expected outcomes of the project include delivery of new methods to optimise particle deposition, development of tunable powder formulations, as well as definition of particle-surface interaction mechanisms in flows. The project should provide significant benefits to particle systems for applications ranging from additive manufacturing to aerosol delivery.Read moreRead less
Multi-drug dry powder inhalation systems for the effective treatment of chronic obstructive pulmonary disease. Utilising a combination of particle engineering, computer modeling, rapid prototyping and high-speed 3D imaging this project will develop a novel approach to treat chronic obstructive pulmonary disease. A multi-drug particle system whose surface is independent of the drugs incorporated will be optimised in a novel high efficiency inhalation device.