Roles for quorum sensing and biofilm formation by Vibrio cholerae in resistance to protozoan grazing. This research will benefit Australia through an increased fundamental understanding of how our model bacterium, Vibrio cholerae, survives in the environment. This could lead to the development of strategies that control bacterial biofilms, a significant medical and industrial concern. This project will also be of benefit through the training of postgraduate students in environmental microbiology ....Roles for quorum sensing and biofilm formation by Vibrio cholerae in resistance to protozoan grazing. This research will benefit Australia through an increased fundamental understanding of how our model bacterium, Vibrio cholerae, survives in the environment. This could lead to the development of strategies that control bacterial biofilms, a significant medical and industrial concern. This project will also be of benefit through the training of postgraduate students in environmental microbiology and is expected to result in the publication and presentation of data in quality journals and conferences, which increases the profile of Australian science.Read moreRead less
Unlocking bacterial shapeshifting and its role in antimicrobial resistance. This project aims to combine advanced imaging with innovative microfluidics to identify how microbial shapeshifting can be exploited as a target for new antimicrobials. Infections that are hard to treat due to increasing antimicrobial resistance not only have an enormous, global impact on mammalian health, including livestock and humans, but also carry a growing economic burden. Advanced understanding of microbial life c ....Unlocking bacterial shapeshifting and its role in antimicrobial resistance. This project aims to combine advanced imaging with innovative microfluidics to identify how microbial shapeshifting can be exploited as a target for new antimicrobials. Infections that are hard to treat due to increasing antimicrobial resistance not only have an enormous, global impact on mammalian health, including livestock and humans, but also carry a growing economic burden. Advanced understanding of microbial life can propel urgently needed progress this area. Specifically, the project outcomes are expected to aid the development of next generation antibiotics. The new fundamental knowledge should also benefit translational prevention, identification and management efforts of a rising national and global health threat.Read moreRead less