We have discovered a single tumour factor which causes cancer cachexia, a wasting condition that is one of the worst complications of malignancy, for which there is no current effective treatment. We have developed antibodies which effectively block this condition in preclinical models and have produced human/humanised version of this. This application is to characterise these human antibodies to allow us proceed to clinical trials.
Locating LGBTIQ+ youth in the archive: Telling new stories for belonging. This project aims to produce the first study of LGBTIQ+ youth in Australia’s past and investigate what these histories mean to LGBTIQ+ youth today. We will generate new knowledge of Australian LGBTIQ+ history and links between historical knowledge and wellbeing in relation to LGBTIQ+ youth. Working with LGBTIQ+ youth we will also develop new archival storytelling techniques, theorising archives as ‘laboratories of belongin ....Locating LGBTIQ+ youth in the archive: Telling new stories for belonging. This project aims to produce the first study of LGBTIQ+ youth in Australia’s past and investigate what these histories mean to LGBTIQ+ youth today. We will generate new knowledge of Australian LGBTIQ+ history and links between historical knowledge and wellbeing in relation to LGBTIQ+ youth. Working with LGBTIQ+ youth we will also develop new archival storytelling techniques, theorising archives as ‘laboratories of belonging’. In doing so, the project forges links between cultural studies of storytelling, LGBTIQ+ youth studies and Australian history. Benefits include innovations in reparative historical methodologies, new resources for the GLAM, youth and education sectors and improvements in LGBTIQ+ youth wellbeing.Read moreRead less
Helping Central Banks Measure Unobserved Variables Using Real-time Forecasts. The project addresses structural measurement problems confronted routinely by central bankers. The techniques developed, and the estimates provided, will aid directly the Partner Organisations (the Reserve Bank of Australia, the Reserve Bank of New Zealand and Norges Bank) and other central banks in formulating monetary policy. The analysis will allow interest rates in Australia and elsewhere to be set with greater pre ....Helping Central Banks Measure Unobserved Variables Using Real-time Forecasts. The project addresses structural measurement problems confronted routinely by central bankers. The techniques developed, and the estimates provided, will aid directly the Partner Organisations (the Reserve Bank of Australia, the Reserve Bank of New Zealand and Norges Bank) and other central banks in formulating monetary policy. The analysis will allow interest rates in Australia and elsewhere to be set with greater precision. The techniques developed in this project will facilitate the understanding and communication of monetary policy within the central banks concerned, and enhance communication of monetary policy strategy to the public.Read moreRead less
Discovering a ‘good read’: Pathways to reading for Australian teens. This project aims to support the school, library, and book industries to increase teenagers’ recreational reading. Matching the right book to the right reader is essential to increase young people’s motivation to read. Yet how cultural intermediaries should operate to best effect within the complex ecologies that shape young people’s text selection is unclear. The project expects to generate robust evidence on how teens discove ....Discovering a ‘good read’: Pathways to reading for Australian teens. This project aims to support the school, library, and book industries to increase teenagers’ recreational reading. Matching the right book to the right reader is essential to increase young people’s motivation to read. Yet how cultural intermediaries should operate to best effect within the complex ecologies that shape young people’s text selection is unclear. The project expects to generate robust evidence on how teens discover books and the cultural factors that influence their choices. Expected outcomes include strategies that libraries, schools, and the book industry can use to promote Australian content for young adults, and equip young people to participate more fully in the social and economic benefits of pleasure reading.Read moreRead less
Towards a superannuation system fit for the future. Towards a superannuation system fit for the future. This project aims to develop a stochastic superannuation model and propose alternative post retirement solutions, using data-led understanding of savings habits. Funding for the increasing cost of the growing older population will, if not modelled, forecast and managed adequately, swamp all other welfare and state funded costs. To manage older age costs adequately, governments need to encourag ....Towards a superannuation system fit for the future. Towards a superannuation system fit for the future. This project aims to develop a stochastic superannuation model and propose alternative post retirement solutions, using data-led understanding of savings habits. Funding for the increasing cost of the growing older population will, if not modelled, forecast and managed adequately, swamp all other welfare and state funded costs. To manage older age costs adequately, governments need to encourage people to save and provide ways people can save—but need to better understand how people save money for their old age. This research is expected to enable the “superannuation change“ necessary for the superannuation system to remain sustainable and fund retirees to live well.Read moreRead less
Engaging ethnic minority and majority blood donors in donor recruitment. Word-of-mouth is a potentially powerful way to recruit blood donors. Talking about donation increases awareness, trust, commitment and positive feelings about donating, particularly in ethnic minority groups. However, donors seldom tell others about donating. This project aims to determine how to motivate blood donors to recruit new donors using word-of-mouth, through research comprising co-design, surveys, and experiments. ....Engaging ethnic minority and majority blood donors in donor recruitment. Word-of-mouth is a potentially powerful way to recruit blood donors. Talking about donation increases awareness, trust, commitment and positive feelings about donating, particularly in ethnic minority groups. However, donors seldom tell others about donating. This project aims to determine how to motivate blood donors to recruit new donors using word-of-mouth, through research comprising co-design, surveys, and experiments. This project will generate new knowledge of how to encourage effective word-of-mouth for pro-social behaviours. Expected outcomes include producing culturally relevant, validated resources that will significantly benefit Australia by encouraging effective conversations to promote blood donation in all communities.Read moreRead less
Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessmen ....Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessment of the distributional impact of a wide range of possible reforms, including how the outcomes of any policy change will affect disadvantaged sections of our society, whether different generations will be fairly treated, and the impact by gender.Read moreRead less
Developing a responsive regulatory system for Australia's small corporations. Small corporations employ approximately 50% of Australia's 10.5 million employed persons (ABS: Nov 2007). Promoting and maintaining small corporations is vital to the health of the Australian economy and the well being of society. This research will strengthen Australia's social and economic fabric by identifying, in consultation with regulators, industry leaders, government, the ideal regulatory environment for Aust ....Developing a responsive regulatory system for Australia's small corporations. Small corporations employ approximately 50% of Australia's 10.5 million employed persons (ABS: Nov 2007). Promoting and maintaining small corporations is vital to the health of the Australian economy and the well being of society. This research will strengthen Australia's social and economic fabric by identifying, in consultation with regulators, industry leaders, government, the ideal regulatory environment for Australia's small corporations. A responsive regulatory framework will enable small corporations to conduct business more efficiently and profitably allowing for and creating structures and processes for encouraging and managing innovation creativity in this vital sector.Read moreRead less
Eddy-resolving global ocean-sea ice modelling. Eddy-resolving global ocean-sea ice modelling. This project aims to develop a world-class global ocean-sea ice model framework through a nationwide consortium. The resulting high resolution models are expected to provide the foundation for the next decade of Australian ocean-sea ice modelling capacity. This research should lead to improved ocean and sea ice prediction, ocean reanalyses, and climate projections, enhancing Australia's capacity to pred ....Eddy-resolving global ocean-sea ice modelling. Eddy-resolving global ocean-sea ice modelling. This project aims to develop a world-class global ocean-sea ice model framework through a nationwide consortium. The resulting high resolution models are expected to provide the foundation for the next decade of Australian ocean-sea ice modelling capacity. This research should lead to improved ocean and sea ice prediction, ocean reanalyses, and climate projections, enhancing Australia's capacity to predict the ocean state on timescales of days to decades. This is expected to yield efficiencies in shipping, marine search and rescue and naval operations, and increase the accuracy of projected future changes in climate, sea level, ocean ecosystems and the cryosphere.Read moreRead less