Australian Partnership (for) Preparedness Research On InfectiouS (disease) Emergencies (APPRISE)
Funder
National Health and Medical Research Council
Funding Amount
$4,996,416.00
Summary
We have assembled national experts in clinical, laboratory and public health research to ensure Australia is equipped for a coordinated, effective and evidence based response to infectious diseases. This multidisciplinary team will create and share new knowledge to detect, prevent and manage emerging infection threats. We will train a robust cross-sectoral work force and develop sustainable research capacity integrated within the health system to ensure national and regional health security.
Intermittent Preventive Treatment In Pregnancy With Sulphadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine To Reduce Adverse Pregnancy Outcomes And Prevent Malaria In Papua New Guinea: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,938,453.00
Summary
Millions of pregnancies are complicated by malaria worldwide. Monthly sulphadoxine-pyrimethamine (SP) treatments, the current treatment strategy, no longer protects from malaria but improves birth outcomes through non-malarial effects. Dihydroartemisinin-piperaquine clears malaria but babies are smaller compared to women who received SP. A clinical trial of their combination has potential to substantially improve health outcomes for women and babies in Papua New Guinea and beyond.
Estimating fishing-related mortality and designing sustainable management protocols for shark fisheries in Northern Australia. Sharks are extremely valuable economically, with the landed catch in the NT alone exceeding $10 million in 2004. The increasing world demand for high-quality protein will necessitate appropriate management so that over-exploitation does not occur as it has in most other shark fisheries worldwide. The proposed project will provide key information that will direct careful ....Estimating fishing-related mortality and designing sustainable management protocols for shark fisheries in Northern Australia. Sharks are extremely valuable economically, with the landed catch in the NT alone exceeding $10 million in 2004. The increasing world demand for high-quality protein will necessitate appropriate management so that over-exploitation does not occur as it has in most other shark fisheries worldwide. The proposed project will provide key information that will direct careful and informed management decisions well into the future. The added benefit of collecting information on the rarer and more susceptible non-target species caught in this fishery will ensure that any negative impacts are reduced. The project will also provide information on the potential impact of illegal fishing by neighbouring countries to our north.Read moreRead less
Effects of maternal foraging success and oceanographic variation on offspring behaviour and survival in the southern elephant seal. Juvenile survival is the key determinant of mammalian population performance, but the proximate determinants of this have rarely been established in large, long-lived predators. Southern elephant seals, with their concentrated lactation effort and marked separation of energy acquisition (at-sea foraging) and expenditure (on-land lactation) provide an ideal model for ....Effects of maternal foraging success and oceanographic variation on offspring behaviour and survival in the southern elephant seal. Juvenile survival is the key determinant of mammalian population performance, but the proximate determinants of this have rarely been established in large, long-lived predators. Southern elephant seals, with their concentrated lactation effort and marked separation of energy acquisition (at-sea foraging) and expenditure (on-land lactation) provide an ideal model for investigating these factors. In this study, we investigate the partitioning of pre-partum performance (fat acquired in mothers) relative to spatial-temporal variation in ocean productivity and the effect of this expenditure on offspring condition and survival. Here, the final missing link of energy transfer and its effects on offspring will be a major outcome of this project.Read moreRead less
A Randomised Controlled Trial Of Alternative Treatments To Intramuscular Penicillin For Impetigo In Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$1,326,182.00
Summary
We will conduct clinical trials to find an effective, simple and cheap oral alternative to injected penicillin for skin sores which could become the universal standard of care whether the patient is in Melbourne or Milingimbi. It would also likely be adopted by the World Health Organization as a standard of care for developing countries. This would lead directly to a reduced burden of skin sores and their complications. It would also open the way for studies to explore even simpler regimens.
A framework for adapting child interview protocols in complex cases. This project aims to develop–in collaboration with Aboriginal and other industry co-researchers–a ‘how to’ framework for effectively adapting standard child abuse interview protocols to accommodate the complexities that create barriers to disclosure. Complex cases necessitate interview adaption, but it requires systematic guidance and an interdisciplinary, practitioner-driven approach to be effective. This innovative framework ....A framework for adapting child interview protocols in complex cases. This project aims to develop–in collaboration with Aboriginal and other industry co-researchers–a ‘how to’ framework for effectively adapting standard child abuse interview protocols to accommodate the complexities that create barriers to disclosure. Complex cases necessitate interview adaption, but it requires systematic guidance and an interdisciplinary, practitioner-driven approach to be effective. This innovative framework is expected to have long-term benefits for services that support children’s well-being, through improvements in the quality of evidence underpinning decisions. By enhancing interviewer capability, there will also be fewer cases prematurely exiting the justice system before forensic interview or investigation.Read moreRead less
Mapping the health promoting capacity of art centres on the Anangu Pitjantjatjara Yankunytjatjara Lands. This project will identify the health promoting benefits of art centres managed by Ananguku Arts on the Anangu Pitjantjatjara Yankunytjatjara Lands. The project will identify the social health benefits derived from Art Centres such as increased income, employment opportunities, education, cultural maintenance and community governance.
Indigenous Futurity: Milpirri as Experimental Ceremony. This project aims to develop a long-term research partnership between Warlpiri Indigenous knowledge holders, anthropologists, and community arts industry partner Tracks Dance Company. It will investigate Milpirri Festival as arts innovation, engaging community-members in collective responsibility for Indigenous heritage and futurity. The project will generate new knowledge of Milpirri song, dance, art and story through practice-based rese ....Indigenous Futurity: Milpirri as Experimental Ceremony. This project aims to develop a long-term research partnership between Warlpiri Indigenous knowledge holders, anthropologists, and community arts industry partner Tracks Dance Company. It will investigate Milpirri Festival as arts innovation, engaging community-members in collective responsibility for Indigenous heritage and futurity. The project will generate new knowledge of Milpirri song, dance, art and story through practice-based research with benefits for industry partners and Lajamanu community of increased community participation, outreach and impact.Read moreRead less
Impact Of DTP Schedules On The Immunogenicity Of 2 Doses Of 13v-PCV Followed By An Early Booster
Funder
National Health and Medical Research Council
Funding Amount
$2,651,687.00
Summary
This project aims to come up with a vaccination schedule to make pneumococcal vaccines more effective and affordable for Fiji and other developing countries. We will evaluate schedules involving a 2 dose primary series in early infancy with a booster at 9 months of age. We will compare the immune responses to 3 different primary series and 2 booster options. The results of this project will be used to provide advice, at global and country levels, regarding introduction of pneumococcal vaccines.