Teaching An Old Brain New Tricks: Optimising Cognitive Training Through Neuroplasticity
Funder
National Health and Medical Research Council
Funding Amount
$1,562,250.00
Summary
People with early dementia have the most to gain from brain training programs aimed at delaying deterioration. Yet, its power is under-realised, with improvements not generalising to everyday living. This research program will harness the power of neuroplasticity to optimise brain training so that the effects transfer to everyday life. The knowledge gained will transform the way that we design and deliver brain training programs and revolutionise our understanding of why and how people respond.
Evaluating the Network Neuroscience of Human Cognition to Improve AI. This project will translate the brain’s inherent complexity into a set of explorable networks that will test the network theory of intelligence, and also be used to drive advances in next generation artificial neural networks. Our approach will catalyse new knowledge regarding how the complexity of the brain gives rise to cognition using innovative analyses inspired by physics and engineering. This fresh perspective on cogniti ....Evaluating the Network Neuroscience of Human Cognition to Improve AI. This project will translate the brain’s inherent complexity into a set of explorable networks that will test the network theory of intelligence, and also be used to drive advances in next generation artificial neural networks. Our approach will catalyse new knowledge regarding how the complexity of the brain gives rise to cognition using innovative analyses inspired by physics and engineering. This fresh perspective on cognition will accelerate understanding of normal cognitive function and also advance the development of advances in artificial neural network performance. Expected outcomes include methods to describe the computational signature of how cognition emerges from dynamic brain network activity and novel AI algorithms. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100608
Funder
Australian Research Council
Funding Amount
$457,810.00
Summary
Characterising brain networks of intelligence through information tracking. For intelligent behaviour, the human brain needs to engage several processes including sensory, memory and motor processes. How it does this is one of the most significant questions in cognitive neuroscience. This project characterises the neural networks of human intelligence by advancing and building on the most recent advances in neuroimaging analyses. It will determine the interaction of different brain processes by ....Characterising brain networks of intelligence through information tracking. For intelligent behaviour, the human brain needs to engage several processes including sensory, memory and motor processes. How it does this is one of the most significant questions in cognitive neuroscience. This project characterises the neural networks of human intelligence by advancing and building on the most recent advances in neuroimaging analyses. It will determine the interaction of different brain processes by developing novel connectivity methods that track the flow of information through the brain with high temporal and spatial accuracy. The outcomes will be fundamental insights into the mechanisms of human intelligence and new connectivity analysis software that will have wide application in brain research.Read moreRead less
Non-invasive Detection Of Hypoglycaemia In People With Diabetes Using Brain Wave Activity
Funder
National Health and Medical Research Council
Funding Amount
$330,447.00
Summary
Hypoglycaemia remains a major cause of morbidity and mortality in people with both type 1 diabetes and type 2 diabetes who require insulin therapy. Current treatments for nocturnal hypoglycaemia are usually ineffective. Combining brain wave recording and artificial intelligence, we will identify the changes that precipitate an episode of hypoglycaemia allowing the development of a non-invasive device to prevent or alleviate these fearful and potentially life-threatening events.
A Large-scale Clinical Effectiveness (health Services) Trial To Determine Whether Personalised Health Care Packages, Combined With Digitally-supported Measurement-based Care, Improve Functional Outcomes In Young People With Mood Disorders
Funder
National Health and Medical Research Council
Funding Amount
$3,434,588.00
Summary
One of our greatest current health challenges is to develop highly-personalised interventions for teenagers and young adults with emerging mood disorders. This research will combine our national expertise to develop and implement care packages utilising digital technologies, personalised assessment techniques, targeted treatment choices, and long-term outcome tracking. In a clinical trial we will assess the clinical effectiveness of these innovative healthcare packages.
Social buffering of fear inhibition in adolescent rats. Adolescence is an important time when individuals learn to manage stress-related emotions like fear. Peers can help, or hinder, individuals to regulate fear. This project aims to understand how, when, and for whom social buffering of fear regulation occurs during adolescence. It uses a behavioural, pharmacological, and neural approach to explore these issues. The project aims to close the gap in understanding of how social companions affect ....Social buffering of fear inhibition in adolescent rats. Adolescence is an important time when individuals learn to manage stress-related emotions like fear. Peers can help, or hinder, individuals to regulate fear. This project aims to understand how, when, and for whom social buffering of fear regulation occurs during adolescence. It uses a behavioural, pharmacological, and neural approach to explore these issues. The project aims to close the gap in understanding of how social companions affect basic learning and memory processes in an understudied population of adolescents. The expected outcomes of this project include a richer knowledge of how peers shape emotional regulation during development, which will ultimately inform social-based approaches for improving emotion regulation in youth.
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Circulating Tumour DNA To Monitor Treatment Response And Resistance In Chronic Lymphocytic Leukaemia
Funder
National Health and Medical Research Council
Funding Amount
$876,950.00
Summary
Many cancers shed small amounts of DNA (ctDNA) into the patient’s bloodstream and recent advances in genomic technologies now allow levels of ctDNA to be accurately measured in the blood. Changes in ctDNA levels have potential to be used as specific markers of disease progression and/or response to cancer therapy. This project will evaluate if ctDNA can be used to monitor treatment responses and individualise treatment decisions in patients with chronic lymphocytic leukaemia.
I-HEART - Implementation Of HEArt Failure Guidelines In Regional AusTralia
Funder
National Health and Medical Research Council
Funding Amount
$1,266,173.00
Summary
Heart failure (HF) is a common disease of the heart with a high rehospitalisation and mortality rate. Regional HF patients rarely receive the full benefits of evidence-based care simply due to inaccessibility to a HF specialist team. This translational project will implement key recommendations from clinical guidelines in regional health services and improve access to specialist services. It has the potential to keep patients out of hospital and save lives.