Precision Pulsar Timing and its Applications. The rapidly rotating pulsars known as millisecond pulsars have period stabilities which rival that of the best terrestrial clocks. Observations of many millisecond pulsars spread across the sky should allow detection of the gravitational-wave background - likely to be the first direct detection of gravity waves. It will also enable establishment of a long-term time standard which is independent of and probably superior to that derived from terrestria ....Precision Pulsar Timing and its Applications. The rapidly rotating pulsars known as millisecond pulsars have period stabilities which rival that of the best terrestrial clocks. Observations of many millisecond pulsars spread across the sky should allow detection of the gravitational-wave background - likely to be the first direct detection of gravity waves. It will also enable establishment of a long-term time standard which is independent of and probably superior to that derived from terrestrial clocks. New analysis techniques and establishment of an international observing network will be required. Investigation and application of techniques for overcoming radio interference will be an important part of the project.Read moreRead less
Defeating Radio Frequency Interference. The radio spectrum is a valuable resource. Development of techniques which minimize the impact of various users on one another, allowing this resource to be shared, will benefit the entire community. For astronomy in particular, shared use is essential because of the very wide bandwidths needed to obtain sufficient sensitivity. Usage of the radio spectrum is increasing rapidly and radio telescopes are becoming more and more sensitive, compounding the probl ....Defeating Radio Frequency Interference. The radio spectrum is a valuable resource. Development of techniques which minimize the impact of various users on one another, allowing this resource to be shared, will benefit the entire community. For astronomy in particular, shared use is essential because of the very wide bandwidths needed to obtain sufficient sensitivity. Usage of the radio spectrum is increasing rapidly and radio telescopes are becoming more and more sensitive, compounding the problems. The digital signal processing techniques developed under this project will be widely applicable, not only to future radio astronomy facilities such as the Square Kilometer Array, but also to the communications industry generally.Read moreRead less
A Future Beyond the Wall: Improving Post-release Employment Outcomes for People Leaving Prison. Engaging in meaningful work has been shown to reduce re-offending by ex-prisoners, but few prison releasees internationally or in Australia gain employment, and successful pathways to employment for this group are poorly researched and understood. This study aims to gather and analyse, for the first time, comparative data from Australian jurisdictions and employment agencies on the relationship betwee ....A Future Beyond the Wall: Improving Post-release Employment Outcomes for People Leaving Prison. Engaging in meaningful work has been shown to reduce re-offending by ex-prisoners, but few prison releasees internationally or in Australia gain employment, and successful pathways to employment for this group are poorly researched and understood. This study aims to gather and analyse, for the first time, comparative data from Australian jurisdictions and employment agencies on the relationship between in-prison and post-prison vocational education and employment programs, employment and recidivism. It aims to identify effective elements, strategies, program and policy directions in offender training and employment. This is a unique partnership amongst key academics in the field, peak national bodies, correctional and employment organisations.Read moreRead less
Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites ....Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites to survive in the new host. Anticipated outcomes include the identification of new intervention strategies and improved transmission model systems for vector-borne diseases. This gained knowledge could provide benefits to future biomedical applications by informing diagnostics or treatment of lipid associated diseases.Read moreRead less
Cascades of Violence and Nonviolence. Why did the Arab Spring spread so fast? Why did so many communist regimes collapse so quickly in 1989? This project explains why tactics of violence and of nonviolence cause contagion. It develops a new evidence-based theory of how to contain cascades of violence and accelerate contagions of nonviolence to create a less violent world.
Optimising illicit dark net marketplace interventions. Optimising illicit dark net marketplace interventions. This project aims to develop and test a series of interventions to disrupt identify theft activities, and design an operational risk framework that will aid law enforcement agencies and organisations to timely and appropriately intervene in cyber space. The buying and selling of identity credentials via dark net forums is a significant and growing problem. This research— based on systems ....Optimising illicit dark net marketplace interventions. Optimising illicit dark net marketplace interventions. This project aims to develop and test a series of interventions to disrupt identify theft activities, and design an operational risk framework that will aid law enforcement agencies and organisations to timely and appropriately intervene in cyber space. The buying and selling of identity credentials via dark net forums is a significant and growing problem. This research— based on systems analyses of dark net forums, and bringing together researchers, practitioners, theories and methods from human factors, sociotechnical systems, criminology, and cyber security—is expected to increase understanding of the dark net and improve ways of disrupting identity theft and trading.Read moreRead less
Automated internet warnings to prevent viewing of minor-adult sex images. Since the advent of the internet and digital cameras, the market for child exploitation material (CEM) has boomed. This project aims to explore how the visual appearance of warning messages influences internet users. It plans to conduct a randomised controlled experiment with naïve participants on a real-life website to test the effectiveness of messages designed to discourage viewers of legal ‘barely legal’ pornography. I ....Automated internet warnings to prevent viewing of minor-adult sex images. Since the advent of the internet and digital cameras, the market for child exploitation material (CEM) has boomed. This project aims to explore how the visual appearance of warning messages influences internet users. It plans to conduct a randomised controlled experiment with naïve participants on a real-life website to test the effectiveness of messages designed to discourage viewers of legal ‘barely legal’ pornography. It is anticipated that results will assist policing efforts by indicating whether warnings can be used to dissuade first-time CEM viewers and whether differences exist between harm or deterrent-focused messages.Read moreRead less
Aboriginal and non-Aboriginal sex-offenders in Australia: Assessing risk for practice and policy. A key priority of Australian governments is to improve community safety through reducing the risk of sex offenders re-offending after release from prison. This project will assess the validity of tools used to predict the risk of sexual offender recidivism and identify alternate risk assessment tools for Indigenous and non-Indigenous sex offenders.
Preventing gendered violence: lessons from the global south. This project aims to study the establishment of police stations for women in Argentina as a key element to preventing gendered violence. This project aims to discover the extent to which the Argentinian interventions prevent the occurrence of gendered violence, and identify aspects that could inform the development of new approaches to preventing gendered violence in Australia. Anticipated outcomes include knowledge critical to develo ....Preventing gendered violence: lessons from the global south. This project aims to study the establishment of police stations for women in Argentina as a key element to preventing gendered violence. This project aims to discover the extent to which the Argentinian interventions prevent the occurrence of gendered violence, and identify aspects that could inform the development of new approaches to preventing gendered violence in Australia. Anticipated outcomes include knowledge critical to developing and implementing new ways to prevent gendered violence, with long-term benefits for national health, wellbeing and productivity.Read moreRead less
Improving Treatment Strategies For Chronic Alphaviral Arthritic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$643,624.00
Summary
Chikungunya virus and Ross River virus cause epidemics of acute and chronic arthritic disease in humans, which is often poorly managed with current treatments. This grant seeks to understand the mechanisms that give rise to disease in order to identify improved treatment strategies. Both the persistence of viral replication in joint tissues and unnecessary inflammatory responses appear to be important factors driving chronic disease.