ARC Centre of Excellence - Structural and Functional Microbial Genomics. The research falls under the National Research Priority Frontier Technologies for Building and Transforming Australian Industries, with the priority goal of frontier technologies. The research has commercial applications, such as the development of novel antimicrobials and vaccines, with potentially enormous impact in the biotechnology area of biomedical health and the primary industries. In addition, the project will use ....ARC Centre of Excellence - Structural and Functional Microbial Genomics. The research falls under the National Research Priority Frontier Technologies for Building and Transforming Australian Industries, with the priority goal of frontier technologies. The research has commercial applications, such as the development of novel antimicrobials and vaccines, with potentially enormous impact in the biotechnology area of biomedical health and the primary industries. In addition, the project will use state-of-the-art technology, including use of synchrotron radiation at the Monash-based Australian Synchrotron facility from 2007.Read moreRead less
Special Research Initiatives - Grant ID: SR0354619
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian Microbial Genomics Research Network. The Australian Microbial Genomics Research Network aims to bring together Australian scientists with complementary expertise in microbial genomics within two ARC Centres, a Ramaciotti Centre and four institutions across three states. This initiative will involve the strategy and planning of the proposed Network.
ARC Centre for Structural & Functional Microbial Genomics. Australian Primary Industry will benefit from a team of experts in microbial genetics, bioinformatics and protein structure and function undertaking integrated studies on microbial genomics and phenomics that are focused on fundamental biological processes and host/pathogen interactions. Whole genome expression and protein profiling will be used to characterise genes whose expression is altered in the infected host and to analyse genes i ....ARC Centre for Structural & Functional Microbial Genomics. Australian Primary Industry will benefit from a team of experts in microbial genetics, bioinformatics and protein structure and function undertaking integrated studies on microbial genomics and phenomics that are focused on fundamental biological processes and host/pathogen interactions. Whole genome expression and protein profiling will be used to characterise genes whose expression is altered in the infected host and to analyse genes involved in the control of key cellular processes. The Centre will also determine the shapes of key molecules and their interactions. Practical outcomes will include new veterinary vaccines and the identification of novel antimicrobial targets.Read moreRead less
ARC Centre of Excellence in Synthetic Biology. The ARC Centre of Excellence in Synthetic Biology (CoESB) will provide the technical innovation critical for Australia to develop a vibrant bioeconomy building on the nation’s strengths in agriculture. For thousands of years we have used microbes to create bread, wine, cheese. Now, our Centre will pioneer new approaches to the design of synthetic microbes, enabling the development of custom-designed microbial communities, synthetic organelles and ne ....ARC Centre of Excellence in Synthetic Biology. The ARC Centre of Excellence in Synthetic Biology (CoESB) will provide the technical innovation critical for Australia to develop a vibrant bioeconomy building on the nation’s strengths in agriculture. For thousands of years we have used microbes to create bread, wine, cheese. Now, our Centre will pioneer new approaches to the design of synthetic microbes, enabling the development of custom-designed microbial communities, synthetic organelles and new to nature biological pathways and enzymes. CoESB will combine engineering with molecular biology to design and construct novel biological systems that can convert biomass from agriculture or waste streams to biofuel, bioplastics and other high-value chemicals.Read moreRead less
YhcB, a crucial player in the control of bacterial cell envelope biogenesis. All life depends on a cell envelope to enclose the chemical reactions that make life possible. But how do cell envelopes grow? How each component of the cell envelope is incorporated into the envelope at the right amount and in the right time to prevent cell death, has been a longstanding question in bacteriology. Using a unique combination of high through put genetic screens and biochemical approaches, this project wil ....YhcB, a crucial player in the control of bacterial cell envelope biogenesis. All life depends on a cell envelope to enclose the chemical reactions that make life possible. But how do cell envelopes grow? How each component of the cell envelope is incorporated into the envelope at the right amount and in the right time to prevent cell death, has been a longstanding question in bacteriology. Using a unique combination of high through put genetic screens and biochemical approaches, this project will characterise a key regulator of cell envelope growth in Gram-negative bacteria. Knowledge arising from this research will provide insight into a fundamental process in bacteria, will develop new technology to probe protein interactions, and will provide novel avenues to solve infection in plants, humans and animals.Read moreRead less