Emulsion Stability and Solvent Extraction Equipment Design in the Pharmaceutical Industry. The project aims at developing reliable prediction of large scale performance of liquid extraction columns. This will be done through a study of the columns in operation at GlaxoSmithKline's operation at Port Fairy alkaloids plant. In addition a detailed study of the influence of impurities on the coalescence rate of liquid dispersions will be undertaken as this is an important rate limiting step in colu ....Emulsion Stability and Solvent Extraction Equipment Design in the Pharmaceutical Industry. The project aims at developing reliable prediction of large scale performance of liquid extraction columns. This will be done through a study of the columns in operation at GlaxoSmithKline's operation at Port Fairy alkaloids plant. In addition a detailed study of the influence of impurities on the coalescence rate of liquid dispersions will be undertaken as this is an important rate limiting step in column performance. The benefit to GlaxoSmithKline will be a more efficient and optimised plant. The benefit to Australian processing industries is a reliable method of relating small scale trials to full size column performance which is a significent problem in the minerals industry at present.Read moreRead less
Next Generation of Separation Equipment for Natural Product Extraction. The benefit to GlaxoSmithKline will be the potential to upgrade to a more efficient plant which is important for maintaining their competitive position in this global business. The benefit to other Australian processing industries will be an improved understanding of the performance of membrane contactors when used for natural product separation and more specifically a reliable method for controlling fouling in this type of ....Next Generation of Separation Equipment for Natural Product Extraction. The benefit to GlaxoSmithKline will be the potential to upgrade to a more efficient plant which is important for maintaining their competitive position in this global business. The benefit to other Australian processing industries will be an improved understanding of the performance of membrane contactors when used for natural product separation and more specifically a reliable method for controlling fouling in this type of equipment which is a currently a significant industry problem.Read moreRead less
Environmentally Sustainable Solvents for Natural Pharmaceutical Extraction Processes. Australia supplies 25 per cent of the world's pain relieving medicinal opiates which contributes to a $200 million export industry for Australia. The active pharmaceutical ingredients are extracted and purified at GlaxoSmithKline’s (GSK) Port Fairy processing plant using a solvent extraction based process. Together with GSK the project team aim to examine the use of environmentally sustainable bio-derived natur ....Environmentally Sustainable Solvents for Natural Pharmaceutical Extraction Processes. Australia supplies 25 per cent of the world's pain relieving medicinal opiates which contributes to a $200 million export industry for Australia. The active pharmaceutical ingredients are extracted and purified at GlaxoSmithKline’s (GSK) Port Fairy processing plant using a solvent extraction based process. Together with GSK the project team aim to examine the use of environmentally sustainable bio-derived natural solvents to replace the volatile organic compound (VOC) fossil fuels based solvents used in the current process. Due to environmental and health concerns associated with VOCs the development of alternative solvents will be of great benefit to not only GSK but a range of other processing industries that also use VOC based solvent extraction processes.Read moreRead less
Granulation of hydrophobic powders: design and control of granule structure. This unique project will further enhance Australia's established world-class excellence in granulation research, and will assist in setting up a new school of excellence in granulation at Monash University. The innovative use of normally problematic material properties to produce 'designer granules' is a clear example of a 'Frontier Technologies' that can be used to develop 'Advanced Materials' for the next generation o ....Granulation of hydrophobic powders: design and control of granule structure. This unique project will further enhance Australia's established world-class excellence in granulation research, and will assist in setting up a new school of excellence in granulation at Monash University. The innovative use of normally problematic material properties to produce 'designer granules' is a clear example of a 'Frontier Technologies' that can be used to develop 'Advanced Materials' for the next generation of agricultural, food and pharmaceutical industries, particularly for delivery of hydrophobic drugs. The innovative ideas presented in this proposal are expected to provide multiple opportunities for collaboration with national and international research institutions and pharmaceutical companies. Read moreRead less