Links2HealthierBubs: Influenza And Pertussis Vaccine Effectiveness And Safety In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$676,333.00
Summary
Vaccination during pregnancy can offer protection against severe respiratory disease for infants in the first six months of life. For this reason, influenza and pertussis vaccines are routinely recommended during each pregnancy. Unfortunately, little is known about the ‘real world’ effect of both vaccines. We plan to conduct the largest and most comprehensive study to date to evaluate all vaccines routinely recommended in pregnancy in Australia.
Preventing And Treating Significant Infections In The Community And In Hospitals
Funder
National Health and Medical Research Council
Funding Amount
$328,990.00
Summary
Infections that require hospitalisation are common and a significant event for patients. This research will look at severe influenza and define how protective the influenza vaccination is against hospitalisation. It will also look at preventing healthcare associated infections and in particular those involving antibiotic resistant "superbugs".
Prevalence Of Genital HPV Infection In Males Following Introduction Of Universal Male HPV Vaccination
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
As Australia is the first and only country to implement a free universal school based male human papillomavirus (HPV) vaccination program (in 2013), this project has the unique opportunity to be first to study to assess the effectiveness of the male HPV vaccination program in Australia by measuring a change in the prevalence of HPV among young (aged 17-20) heterosexual and homosexual men following the implementation of the vaccination program.
Evaluation Of The Effectiveness Of The 13-valent Pneumococcal Conjugate Vaccine On Pneumococcal Serotypes Causing Pneumonia In Children
Funder
National Health and Medical Research Council
Funding Amount
$1,137,532.00
Summary
Streptococcus pneumonia (Pneumococcus) is a bug that is a leading cause of childhood morbidity and mortality world-wide. Vaccinations have been recently brought onto the national immunisation program to try and combat this. This study aims to assess the new 13 valent Pneumococcal vaccine by studying its effectiveness in preventing childhood pneumonia in Australia by analysing the strains of Pneumococus in the blood and the fluid surrounding the lining the lung in complicated pneumonia using sens ....Streptococcus pneumonia (Pneumococcus) is a bug that is a leading cause of childhood morbidity and mortality world-wide. Vaccinations have been recently brought onto the national immunisation program to try and combat this. This study aims to assess the new 13 valent Pneumococcal vaccine by studying its effectiveness in preventing childhood pneumonia in Australia by analysing the strains of Pneumococus in the blood and the fluid surrounding the lining the lung in complicated pneumonia using sensitive molecular techniques.Read moreRead less
Travellers Visiting Friends And Relatives: New Approaches To Understanding And Reducing Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$117,331.00
Summary
Travel is the single most important factor in the spread of infections globally and travellers who visit friends and relatives in their country of birth are at increased risk of infections. This project will provide necessary evidence to guide an effective response to reducing travel-associated infectious disease in this target at-risk group.
Centre For Research Excellence In Cervical Cancer Control (C4)
Funder
National Health and Medical Research Council
Funding Amount
$2,486,383.00
Summary
Cervical cancer remains common globally despite over 50 years of Pap testing. Australia led the world in HPV vaccination and in 2017 will be the first to deliver a national screening program based on HPV testing. Our CRE, led by cervical cancer prevention experts at CCNSW,VCS, and Kirby, will marry cross-disciplinary research and evaluation of HPV vaccination and screening to provide solid evidence about these new approaches with a view to ultimately reducing the global burden of this cancer.
Enhancing The Efficacy Of Pneumococcal Vaccination Using A Probiotic Adjuvant
Funder
National Health and Medical Research Council
Funding Amount
$302,123.00
Summary
This study will examine the ability of probiotics to enhance the human immune system response of infants immunised with the pneumococcal conjugate vaccine. Probiotics able to improve the immune system would provide greater protection against pneumococcal disease, a major cause of childhood illness and death of Indigenous Australians and among the developing world.
Effectiveness And Cost-Effectiveness Of HPV Vaccination And HPV-Based Cervical Cancer Screening Strategies In China
Funder
National Health and Medical Research Council
Funding Amount
$420,692.00
Summary
In the absence of preventative initiatives, up to 187,000 women will develop cervical cancer in China every year. However, the disease is preventable using human papillomavirus (HPV) vaccination and primary HPV screening. Building on previous work, we will evaluate the most effective and cost-effective options for cervical cancer prevention, in order to provide an comprehensive evidence base for China’s health decision-makers.
Applied Research In The Prevention And Control Of Infections In The Hospital Setting
Funder
National Health and Medical Research Council
Funding Amount
$174,434.00
Summary
Hospital infections result in increased: (1) length of stay; (2) costs to the healthcare system and individual and (3) morbidity/mortality. Vaccination and hand hygiene are both proven infection control practices. However, compliance rates are still less than ideal. I will study how a new innovative method impacts on uptake of both. Barriers to masks as an infection control strategy will also be examined, as they are one of the few strategies that can be guaranteed to be available in a pandemic.
Does Pneumococcal Vaccination Protect Against Cardiovascular Disease? A Randomised Placebo-controlled Double Blind Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,849,245.00
Summary
Australian researchers have set up a novel multi-centre trial to investigate the effects of the pneumococcal vaccination in reducing heart attacks and stroke. People aged 55 to 61 from 6 sites around Australia will be invited to participate in the study. The selected participants will attend a clinic in their area and will be randomly given the pneumococcal vaccine or a placebo vaccine. Outcomes on the expected 6000 participants will be ascertained by health record linkage with government databa ....Australian researchers have set up a novel multi-centre trial to investigate the effects of the pneumococcal vaccination in reducing heart attacks and stroke. People aged 55 to 61 from 6 sites around Australia will be invited to participate in the study. The selected participants will attend a clinic in their area and will be randomly given the pneumococcal vaccine or a placebo vaccine. Outcomes on the expected 6000 participants will be ascertained by health record linkage with government databases after 4 years.Read moreRead less