Genomic diversity, tolerance and ecology of wildlife disease. This project aims to understand the regulation of viral disease by vertebrate hosts. Viruses are rapidly evolving threats to humans, agriculture and wildlife and understanding of these threats can be transformed by combining the latest genomic, ecological and immune-pathological approaches. This project expects to reveal how hosts manage the bad effects of viruses in natural populations and fill gaps in fundamental knowledge of virus- ....Genomic diversity, tolerance and ecology of wildlife disease. This project aims to understand the regulation of viral disease by vertebrate hosts. Viruses are rapidly evolving threats to humans, agriculture and wildlife and understanding of these threats can be transformed by combining the latest genomic, ecological and immune-pathological approaches. This project expects to reveal how hosts manage the bad effects of viruses in natural populations and fill gaps in fundamental knowledge of virus-host evolution. Anticipated benefits include improved management, risk assessment and decision-making for animal disease and biosecurity in Australia and globally.Read moreRead less
New approaches to understanding the forces driving convergent evolution. This project aims to address the evolutionary biology question of what drives convergent evolution of morphological phenotypes. Leveraging previous research on the phylogenetics of Australian reptiles and amphibians, the project will apply new methodological and analytical tools for quantifying and evaluating morphological diversity in a phylogenetic context. The project expects to test the influence of climate, habitat and ....New approaches to understanding the forces driving convergent evolution. This project aims to address the evolutionary biology question of what drives convergent evolution of morphological phenotypes. Leveraging previous research on the phylogenetics of Australian reptiles and amphibians, the project will apply new methodological and analytical tools for quantifying and evaluating morphological diversity in a phylogenetic context. The project expects to test the influence of climate, habitat and evolutionary history on driving convergent morphological evolution across multiple independent animal groups. The project will address fundamental theories on convergent evolution and will improve public awareness of Australia’s unique animals and their history.Read moreRead less
Phenotypic diversity dynamics at a continental scale. This project aims to build on previous research on the phylogenetics of Australian vertebrate animals to apply sophisticated new methodological and analytical tools for modelling species diversification. Australia is famous for the great diversity and uniqueness of its plants and animals, due in part to 40 million years of relative isolation. The project plans to test the influence of historical climate and habitat shifts on morphological evo ....Phenotypic diversity dynamics at a continental scale. This project aims to build on previous research on the phylogenetics of Australian vertebrate animals to apply sophisticated new methodological and analytical tools for modelling species diversification. Australia is famous for the great diversity and uniqueness of its plants and animals, due in part to 40 million years of relative isolation. The project plans to test the influence of historical climate and habitat shifts on morphological evolution and assembly of the Australian biota. This project could showcase Australia as the best place in the World to rigorously test hypotheses concerning rates of biological diversification at a continental scale.Read moreRead less
Biological diversification across Australia in space and time. This project aims to address fundamental questions about the diversification of Australian species and to have practical and impactful outcomes. It will leverage previous ARC funded research on the phylogenomics of Australian reptiles and amphibians and apply sophisticated analytical tools for quantifying and evaluating biological diversity in multiple dimensions and in a phylogenetic context. The expected outcomes include a publicly ....Biological diversification across Australia in space and time. This project aims to address fundamental questions about the diversification of Australian species and to have practical and impactful outcomes. It will leverage previous ARC funded research on the phylogenomics of Australian reptiles and amphibians and apply sophisticated analytical tools for quantifying and evaluating biological diversity in multiple dimensions and in a phylogenetic context. The expected outcomes include a publicly accessible comprehensive database that will be integrated with the Atlas of Living Australia and rigorous testing of a series of hypotheses concerning how old and recent Australian groups evolved in response to biotic invasions and climate change. Read moreRead less
What is killing the honeybees? The role of RNA viruses. This project aims to determine if the Varroa mite, the most important parasite of honeybees, selects for virulent strains of RNA viruses. Before Varroa’s inevitable arrival in Australia, this project will disentangle the effect of Varroa and the bees’ immune system on the evolution of virulence of bee viruses. Australia’s honeybees are Varroa-naïve and don’t carry virulent viruses. There is a known association between Varroa and colonies dy ....What is killing the honeybees? The role of RNA viruses. This project aims to determine if the Varroa mite, the most important parasite of honeybees, selects for virulent strains of RNA viruses. Before Varroa’s inevitable arrival in Australia, this project will disentangle the effect of Varroa and the bees’ immune system on the evolution of virulence of bee viruses. Australia’s honeybees are Varroa-naïve and don’t carry virulent viruses. There is a known association between Varroa and colonies dying from viruses; however, it is not known what is cause and effect. This project will clarify Varroa’s exact role in the evolution of virulence in RNA viruses. The intended outcome is increased knowledge allowing the design of an effective treatment to prevent the death of honeybee colonies.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL120100074
Funder
Australian Research Council
Funding Amount
$2,175,454.00
Summary
Using biological invasions to understand evolutionary processes. The invasion of cane toads through Australia has been devastating for many native species, but created opportunities for others. The rapid evolutionary responses stimulated by toad invasion provide a uniquely powerful model system with which to explore the broader question of how species adapt to novel challenges.
Nucleomodulin effectors of the environmental pathogen Legionella. This project aims to examine the evolution of Legionella as an intracellular organism and the mechanisms by which the bacteria evade environmental predation by amoebae. Aside from the advancement of knowledge, expected outcomes of this project include a greater understanding of amoebae. This will provide significant benefits, and this knowledge may be used to develop inhibitors of amoebae growth.
Shape-shifting birds: a novel consequence of climate change. This project aims to identify which species are affected by climate change, and whether these changes in their ecology enhance or decrease fitness and survival. Climate change is having drastic effects on animal biology, threatening many species. Recent data suggest that changes in body shape (the size of appendages) is one such effect. By studying the bills and legs of birds this project aims to investigate changes in body shape as a ....Shape-shifting birds: a novel consequence of climate change. This project aims to identify which species are affected by climate change, and whether these changes in their ecology enhance or decrease fitness and survival. Climate change is having drastic effects on animal biology, threatening many species. Recent data suggest that changes in body shape (the size of appendages) is one such effect. By studying the bills and legs of birds this project aims to investigate changes in body shape as a biological response to climate change. This project will model the predicted consequences of changes in body shape on population trends in Australian birds, enabling the prediction of which species are most threatened by climate change, and helping inform conservation priorities.Read moreRead less
Integrating nutritional immunology. What an organism eats affects both its susceptibility to disease and the community of beneficial microorganisms living within its gut. This project will study how nutrition, immunity and the flora of the gut interact, and whether hosts are able to select a diet that optimises their immune response and gut flora in the face of disease challenges.
Evolving with sexually transmitted infections. This project aims to understand how sexually transmitted infections (STIs) affect the evolution of host mating systems. STIs threaten the health of most sexually-reproducing organisms. In evolutionary terms, their mode of transmission imposes distinct selection patterns on hosts. This project will use an Australian beetle and its sexually transmitted mite to investigate how STIs lead to evolutionary changes in host mating behaviour and explore the g ....Evolving with sexually transmitted infections. This project aims to understand how sexually transmitted infections (STIs) affect the evolution of host mating systems. STIs threaten the health of most sexually-reproducing organisms. In evolutionary terms, their mode of transmission imposes distinct selection patterns on hosts. This project will use an Australian beetle and its sexually transmitted mite to investigate how STIs lead to evolutionary changes in host mating behaviour and explore the genetic basis for STI resistance. This project is expected to affect the evolution of host mating biology and lead to sex-specific optimal levels of disease resistance, which can influence disease dynamics and host-disease coevolution.Read moreRead less