Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye. Lipids provide a critical layer in the human tear film that retards evaporation and helps nourish and protect the eye. We will identify the molecules within this essential "oil slick" to better understand dry eye syndrome and the discomfort associated with wearing contact lenses. This may lead to new treatments for dry eye and novel technologies that provide greater comfort for the ~120,00 ....Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye. Lipids provide a critical layer in the human tear film that retards evaporation and helps nourish and protect the eye. We will identify the molecules within this essential "oil slick" to better understand dry eye syndrome and the discomfort associated with wearing contact lenses. This may lead to new treatments for dry eye and novel technologies that provide greater comfort for the ~120,000 Australians who wear contact lenses. This collaborative research directly supports the mission of a respected non-profit organisation (Institute for Eye Research) and will train scientists in world-leading analytical technologies that are essential to Australia's emerging biotechnology industries.Read moreRead less
Learning Medical Image Knowledge. We aim to develop Machine Learning and Knowledge Acquisition techniques for automated recognition of features in medical images, and to provide decision support for diagnosis from medical images. The project is innovative in its use of layered learning, where the computer first learns to recognise low-level image features that are then used to learn more complex features. The project is also innovative in combining a variety of automatic learning methods, includ ....Learning Medical Image Knowledge. We aim to develop Machine Learning and Knowledge Acquisition techniques for automated recognition of features in medical images, and to provide decision support for diagnosis from medical images. The project is innovative in its use of layered learning, where the computer first learns to recognise low-level image features that are then used to learn more complex features. The project is also innovative in combining a variety of automatic learning methods, including relational learning, with human-assisted knowledge acquisition methods. The expected outcomes will be new techniques for image understanding, particularly for our test domain, namely, High Resolution Computed Tomography scans of the lung.Read moreRead less
Feature Detection and Computer-aided Diagnosis with Longitudinal Tracking of Benign Asbestos-Related Pleural Disease in CT images. This project seeks to develop smart and novel feature extraction and knowledge acquisition techniques to assist radiologists in automated diagnosis and assessment of lung diseases. These outcomes will lead to improved delivery of health services in Australia, including in rural regions. They will lead to more accurate assessment of asbestos related pleural diseases f ....Feature Detection and Computer-aided Diagnosis with Longitudinal Tracking of Benign Asbestos-Related Pleural Disease in CT images. This project seeks to develop smart and novel feature extraction and knowledge acquisition techniques to assist radiologists in automated diagnosis and assessment of lung diseases. These outcomes will lead to improved delivery of health services in Australia, including in rural regions. They will lead to more accurate assessment of asbestos related pleural diseases for compensation and treatment and better followup, leading to earlier treatment and better quality of life for patients suffering from lung diseases. The project will also save costs due to automated assessment as well as the potential for fewer patient scans.Read moreRead less