Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.
Impact Of DTP Schedules On The Immunogenicity Of 2 Doses Of 13v-PCV Followed By An Early Booster
Funder
National Health and Medical Research Council
Funding Amount
$2,651,687.00
Summary
This project aims to come up with a vaccination schedule to make pneumococcal vaccines more effective and affordable for Fiji and other developing countries. We will evaluate schedules involving a 2 dose primary series in early infancy with a booster at 9 months of age. We will compare the immune responses to 3 different primary series and 2 booster options. The results of this project will be used to provide advice, at global and country levels, regarding introduction of pneumococcal vaccines.
Understanding The Role Of The Two Major Bacterial Pathogens In The Upper And Lower Airways Of Indigenous Children With Chronic Lung Disease
Funder
National Health and Medical Research Council
Funding Amount
$743,282.00
Summary
Lung infections are a major disease burden worldwide. Indigenous Australians are affected more; adults with severe lung disease can die in their 30s and 40s. These diseases start early, yet no in-depth studies of bacteria causing lung infections in children have been done. Our expert team proposes to use existing lung fluids from nearly 500 children with chronic lung disease (58% Indigenous), and state-of-the-art laboratory methods, to inform the design of vaccines to prevent lung disease.
Centre Of Research Excellence In Infectious Diseases Modelling To Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$2,600,064.00
Summary
Infectious diseases pose a global challenge, with substantial human and economic costs. Mathematical models provide valuable frameworks to assess likely benefits of interventions to control infection spread and burden. Leveraging existing NHMRC support, we will expand modeling capability to inform infectious disease control policy in Australia and our region. Focus areas include vaccine preventable disease, respiratory viruses and emerging pathogens, supported by innovative methods development.
Group A streptococcus (GAS) is a bacteria that causes a wide range of disease in humans. GAS diseases are more common in Australias Indigenous population, and other health and economically disadvantaged groups than more affluent groups. In this study we will evaluate the effectiveness of novel vaccine candidates designed to prevent infection from all strains of GAS.
Greater inclusion of people with disability in Australian workplaces. This project aims to develop a model of successful employment for people with a disability, identify sources of employer diversity that explain willingness to hire, and develop social marketing messages that improve employer attitudes and achieve greater inclusion in Australian workplaces. Workforce participation of people with a disability remains low. The outcome of this study will be more people with a disability and their ....Greater inclusion of people with disability in Australian workplaces. This project aims to develop a model of successful employment for people with a disability, identify sources of employer diversity that explain willingness to hire, and develop social marketing messages that improve employer attitudes and achieve greater inclusion in Australian workplaces. Workforce participation of people with a disability remains low. The outcome of this study will be more people with a disability and their carers gaining meaningful employment, with benefits including improved physical and mental health, social connections and economic security. It will benefit employers by creating more diverse workplaces and a broader talent pool, resulting in greater innovation and productivity.Read moreRead less
The initiation and maintenance of plasma and platelet donation in Australia: An analysis of the role of donor identity and commitment. Australia strives to be self-sufficient in the provision of plasma and platelets in a context where demand is forecast to grow. Our research will be of significant social and applied benefit to Australia in identifying the key psychosocial determinants of plasma and platelet (apheresis) donation initiation and maintenance. In addition, our research will design an ....The initiation and maintenance of plasma and platelet donation in Australia: An analysis of the role of donor identity and commitment. Australia strives to be self-sufficient in the provision of plasma and platelets in a context where demand is forecast to grow. Our research will be of significant social and applied benefit to Australia in identifying the key psychosocial determinants of plasma and platelet (apheresis) donation initiation and maintenance. In addition, our research will design and assess practical interventions to facilitate the recruitment and retention of apheresis donors. Greater understanding of the determinants of apheresis donor behaviour will help to increase the numbers of Australians choosing to become regular apheresis donors. This will allow Australia to ultimately meet its goal of self-sufficiency in providing critical medical resources.Read moreRead less
Business and democracy: Power, profit and participation. The project aims to explain how business influences democracy. While business and democracy are mutually reinforcing domains in any healthy and vibrant society, there are concerns about the way corporations may unduly influence or even curtail democratic processes. This project expects to generate new knowledge on how industry translates economic power into political influence. This includes the development of a new theory of power and a m ....Business and democracy: Power, profit and participation. The project aims to explain how business influences democracy. While business and democracy are mutually reinforcing domains in any healthy and vibrant society, there are concerns about the way corporations may unduly influence or even curtail democratic processes. This project expects to generate new knowledge on how industry translates economic power into political influence. This includes the development of a new theory of power and a methodology for examining political connections. This should provide significant benefits to public dialogue and policymakers concerning the task of strengthening citizen voice and decision-making in Australia and globally. Read moreRead less
Examining the effectiveness of co-creation practices on health outcomes. This projects aims to examine how patients interact collaboratively with multiple stakeholders in a health system (co-creation). Governments and health-care providers continually seek new ways to be more efficient and to create more effective health service outcomes. This research aims to identify why co-creation will be important in the formulation of future health policy. The project plans to assess patient-centred practi ....Examining the effectiveness of co-creation practices on health outcomes. This projects aims to examine how patients interact collaboratively with multiple stakeholders in a health system (co-creation). Governments and health-care providers continually seek new ways to be more efficient and to create more effective health service outcomes. This research aims to identify why co-creation will be important in the formulation of future health policy. The project plans to assess patient-centred practices using qualitative and quantitative health outcome measures and to model the patient’s end-to-end journey by developing new metrics. The intended outcomes are practical guidelines to help health professionals focus on the most effective co-creation activities and interactions. The research aims to determine how co-creation practices shape a service ecosystem by examining the effectiveness of a patient-centred approach on health care service outcomes. Findings will improve the implementation of health care practices.Read moreRead less
Consumer value and disability services: The impact of increased autonomy. This project seeks to explore a key question of the National Disability Insurance Scheme (NDIS): will service provision improve when service users have the ability to choose? In 2016, the NDIS will start rolling out and nearly half a million people with a disability will be able to choose disability services. The project aims to identify changes in objective and perceived consumer value pre-NDIS and post-NDIS, and differen ....Consumer value and disability services: The impact of increased autonomy. This project seeks to explore a key question of the National Disability Insurance Scheme (NDIS): will service provision improve when service users have the ability to choose? In 2016, the NDIS will start rolling out and nearly half a million people with a disability will be able to choose disability services. The project aims to identify changes in objective and perceived consumer value pre-NDIS and post-NDIS, and differences in how market segments use their autonomy and whether this leads to differences in benefits gained from the NDIS. Findings are intended to contribute to a better understanding of when free market mechanisms serve the needs of their citizens better than traditional means of government support.Read moreRead less