Immunomodulatory Vaccines In The Treatment Of Peanut Allergy
Funder
National Health and Medical Research Council
Funding Amount
$678,899.00
Summary
Peanut allergy is the most common cause of food-induced anaphylactic reactions in Australia and is a major burden to our healthcare system. Current clinical practice advice dietary avoidance to prevent fatal anaphylactic responses. We propose the use of an immunomodulatory vaccine to re-write the immune response to peanut antigens, from an allergic to a tolerant phenotype. This study will provide novel insights into rational approaches for manipulating immune memory to food allergens.
Group A Streptococcal Human Challenge Study: Accelerating Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$2,018,741.00
Summary
Infection with group A streptococcus (GAS) is a major cause of morbidity and mortality worldwide, including in the Aboriginal population of Australia. Concerted efforts for vaccine development have been hampered by the absence of a suitable animal model. To address this critical knowledge gap we propose to develop a controlled human infection model of GAS infection. This model will provide a direct pathway for the future appraisal of novel GAS vaccines.
Greater inclusion of people with disability in Australian workplaces. This project aims to develop a model of successful employment for people with a disability, identify sources of employer diversity that explain willingness to hire, and develop social marketing messages that improve employer attitudes and achieve greater inclusion in Australian workplaces. Workforce participation of people with a disability remains low. The outcome of this study will be more people with a disability and their ....Greater inclusion of people with disability in Australian workplaces. This project aims to develop a model of successful employment for people with a disability, identify sources of employer diversity that explain willingness to hire, and develop social marketing messages that improve employer attitudes and achieve greater inclusion in Australian workplaces. Workforce participation of people with a disability remains low. The outcome of this study will be more people with a disability and their carers gaining meaningful employment, with benefits including improved physical and mental health, social connections and economic security. It will benefit employers by creating more diverse workplaces and a broader talent pool, resulting in greater innovation and productivity.Read moreRead less
Business and democracy: Power, profit and participation. The project aims to explain how business influences democracy. While business and democracy are mutually reinforcing domains in any healthy and vibrant society, there are concerns about the way corporations may unduly influence or even curtail democratic processes. This project expects to generate new knowledge on how industry translates economic power into political influence. This includes the development of a new theory of power and a m ....Business and democracy: Power, profit and participation. The project aims to explain how business influences democracy. While business and democracy are mutually reinforcing domains in any healthy and vibrant society, there are concerns about the way corporations may unduly influence or even curtail democratic processes. This project expects to generate new knowledge on how industry translates economic power into political influence. This includes the development of a new theory of power and a methodology for examining political connections. This should provide significant benefits to public dialogue and policymakers concerning the task of strengthening citizen voice and decision-making in Australia and globally. Read moreRead less
Examining the effectiveness of co-creation practices on health outcomes. This projects aims to examine how patients interact collaboratively with multiple stakeholders in a health system (co-creation). Governments and health-care providers continually seek new ways to be more efficient and to create more effective health service outcomes. This research aims to identify why co-creation will be important in the formulation of future health policy. The project plans to assess patient-centred practi ....Examining the effectiveness of co-creation practices on health outcomes. This projects aims to examine how patients interact collaboratively with multiple stakeholders in a health system (co-creation). Governments and health-care providers continually seek new ways to be more efficient and to create more effective health service outcomes. This research aims to identify why co-creation will be important in the formulation of future health policy. The project plans to assess patient-centred practices using qualitative and quantitative health outcome measures and to model the patient’s end-to-end journey by developing new metrics. The intended outcomes are practical guidelines to help health professionals focus on the most effective co-creation activities and interactions. The research aims to determine how co-creation practices shape a service ecosystem by examining the effectiveness of a patient-centred approach on health care service outcomes. Findings will improve the implementation of health care practices.Read moreRead less
Consumer value and disability services: The impact of increased autonomy. This project seeks to explore a key question of the National Disability Insurance Scheme (NDIS): will service provision improve when service users have the ability to choose? In 2016, the NDIS will start rolling out and nearly half a million people with a disability will be able to choose disability services. The project aims to identify changes in objective and perceived consumer value pre-NDIS and post-NDIS, and differen ....Consumer value and disability services: The impact of increased autonomy. This project seeks to explore a key question of the National Disability Insurance Scheme (NDIS): will service provision improve when service users have the ability to choose? In 2016, the NDIS will start rolling out and nearly half a million people with a disability will be able to choose disability services. The project aims to identify changes in objective and perceived consumer value pre-NDIS and post-NDIS, and differences in how market segments use their autonomy and whether this leads to differences in benefits gained from the NDIS. Findings are intended to contribute to a better understanding of when free market mechanisms serve the needs of their citizens better than traditional means of government support.Read moreRead less
Intelligent CRM through Conjoint Data Mining of Heterogeneous Sources. This project aims to investigate and develop techniques to improve customer relationship management (CRM) for public and private organisations. It aims to develop an intelligent framework to assist in adaptive marketing and management of customers. The framework is designed to manage multiple information resources for information sharing, and to synthesise knowledge through visualisation. Intended outcomes are standardised XM ....Intelligent CRM through Conjoint Data Mining of Heterogeneous Sources. This project aims to investigate and develop techniques to improve customer relationship management (CRM) for public and private organisations. It aims to develop an intelligent framework to assist in adaptive marketing and management of customers. The framework is designed to manage multiple information resources for information sharing, and to synthesise knowledge through visualisation. Intended outcomes are standardised XML profiles for the different data sets and business processes, novel techniques for conjoint mining of structured and semi-structured data, and adaptive business intelligence techniques. The results will be validated using large real-world data sets provided by the partner organisation.Read moreRead less
Pro bono service: drivers, delight, dark side and downside for the professional. Pro bono work, common in the professions, is important to Australia's economy. This ground breaking research provides rich insights into why pro bono givers feel unappreciated, unacknowledged, unreciprocated, and often taken advantage of and, importantly, equips professionals with strategies for enhanced outcomes.
Impact Of DTP Schedules On The Immunogenicity Of 2 Doses Of 13v-PCV Followed By An Early Booster
Funder
National Health and Medical Research Council
Funding Amount
$2,651,687.00
Summary
This project aims to come up with a vaccination schedule to make pneumococcal vaccines more effective and affordable for Fiji and other developing countries. We will evaluate schedules involving a 2 dose primary series in early infancy with a booster at 9 months of age. We will compare the immune responses to 3 different primary series and 2 booster options. The results of this project will be used to provide advice, at global and country levels, regarding introduction of pneumococcal vaccines.
Testing trade mark law's image of the consumer. An effective trade mark law is vital both to protect consumers and to allow businesses to build brand recognition. This project seeks to put Australian trade mark law on a firmer empirical footing by bringing together experts from psychology, law and marketing to test the law’s assumptions against actual consumer responses.