Host-tumour interplay in Tasmanian devils with devil facial tumour disease: can immune cells be harnessed for therapy? Tasmanian devils only exist naturally in Tasmania and Devil Facial Tumour Disease, an infectious cancer, could cause the extinction of the Tasmanian devil. This project will determine if Devil Facial Tumour Disease reduces the effectiveness of the devil's immune system and test if activated immune cells can protect against this disease.
ARC/NHMRC Research Network for Parasitology. The ARC Network for Parasitology will focus and coordinate Australia's world class fundamental, strategic and applied parasitology research. This targeted approach will raise Australia's standing in the field, assist in the community's understanding of parasitology and biosecurity and maintain and improve Australia's capacity for keeping its stock, crops, wildlife and people disease-free. On an international scale, the Network will work with other cou ....ARC/NHMRC Research Network for Parasitology. The ARC Network for Parasitology will focus and coordinate Australia's world class fundamental, strategic and applied parasitology research. This targeted approach will raise Australia's standing in the field, assist in the community's understanding of parasitology and biosecurity and maintain and improve Australia's capacity for keeping its stock, crops, wildlife and people disease-free. On an international scale, the Network will work with other countries to develop new technologies for the detection and eradication of parasites. This emphasis will not only protect Australia's borders but will assist our near neighbours and lead to the development of technologies with an economic benefit to Australia.
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Immunisation to protect against transmissible cancers in Tasmanian devils. This project aims to identify the immune escape mechanisms that the transmissible cancers, Devil Facial Tumour Disease (DFTD) use to avoid being killed by the immune system. Since the discovery of the second transmissible cancer (DFT2) mystery surrounds whether the devils immune system can respond to this cancer, hence this project will investigate the immune response to DFT2. The final aims are to develop a vaccine with ....Immunisation to protect against transmissible cancers in Tasmanian devils. This project aims to identify the immune escape mechanisms that the transmissible cancers, Devil Facial Tumour Disease (DFTD) use to avoid being killed by the immune system. Since the discovery of the second transmissible cancer (DFT2) mystery surrounds whether the devils immune system can respond to this cancer, hence this project will investigate the immune response to DFT2. The final aims are to develop a vaccine with the potential to protect healthy devils and cure devils with DFTD.Read moreRead less
Mitigating ecosystem impacts by improving the way we breed and manage devils. The Tasmanian ecosystem faces irreversible change due to the decline of the apex predator. An insurance population of Tasmanian devils has been established to prevent extinction of the species. Using the latest sequencing technologies the project aims to determine whether the Tasmanian ecosystem can be restored with Tasmanian devils that are more resilient to a changing environment by improving the way that devils are ....Mitigating ecosystem impacts by improving the way we breed and manage devils. The Tasmanian ecosystem faces irreversible change due to the decline of the apex predator. An insurance population of Tasmanian devils has been established to prevent extinction of the species. Using the latest sequencing technologies the project aims to determine whether the Tasmanian ecosystem can be restored with Tasmanian devils that are more resilient to a changing environment by improving the way that devils are bred and managed in captivity.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100089
Funder
Australian Research Council
Funding Amount
$490,000.00
Summary
Connecting big data with high performance computing for climate science. Connecting big data with high performance computing for climate science: The ARC Centre of Excellence for Climate System Science is a key user of the National Computational Infrastructure facility (NCI). This research requires massive data integrated with high performance computing in an operational facility. Fast disk capacity that is simultaneously connected to NCI long-term storage, cloud and high performance computing s ....Connecting big data with high performance computing for climate science. Connecting big data with high performance computing for climate science: The ARC Centre of Excellence for Climate System Science is a key user of the National Computational Infrastructure facility (NCI). This research requires massive data integrated with high performance computing in an operational facility. Fast disk capacity that is simultaneously connected to NCI long-term storage, cloud and high performance computing severely limits use of the NCI. To resolve this limitation, 1.7 petabytes of storage will be installed to transform the efficiency of the facility. This will enable more ambitious science to be undertaken. This investment will be used to launch a transformation from petascale to exascale problems and communicate the lessons learned to other research communities in Australia.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882682
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
The Australasian Pollen and Spore Atlas. The results generated in this project will enhance Australian research capabilities across multiple disciplines by providing access to key knowledge of pollen and spores in our region. A unified approach to the archiving, presentation and accessibility to existing and evolving databases will provide a considerably improved context for identification and knowledge pooling of any given pollen or spore type. This will create a nexus for novel interactions be ....The Australasian Pollen and Spore Atlas. The results generated in this project will enhance Australian research capabilities across multiple disciplines by providing access to key knowledge of pollen and spores in our region. A unified approach to the archiving, presentation and accessibility to existing and evolving databases will provide a considerably improved context for identification and knowledge pooling of any given pollen or spore type. This will create a nexus for novel interactions between researchers and end users of these data from within and beyond Australia's borders.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775621
Funder
Australian Research Council
Funding Amount
$494,000.00
Summary
Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addi ....Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the earth.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882938
Funder
Australian Research Council
Funding Amount
$1,430,000.00
Summary
MIRA Widefield Array: a new low frequency telescope. A new radio-quiet site for international radio astronomy is being developed at Boolardy in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In additi ....MIRA Widefield Array: a new low frequency telescope. A new radio-quiet site for international radio astronomy is being developed at Boolardy in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the Earth. Read moreRead less